Results 81 to 90 of about 22,445 (236)

Ceramide generation as a novel biological mechanism for chemo-preventive and cytotoxic effects of hesperidin on HT-144 melanoma cells

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2018
Introduction: Hesperidin and its aglycone, hesperetin are abundant natural flavonoid in Citrus and known for their anti-neoplastic and pro-apoptotic properties.
Mahdi Mashhadi Akbar Boojar   +3 more
doaj   +1 more source

Hesperidin enhances intestinal barrier function in Caco‐2 cell monolayers via AMPK‐mediated tight junction‐related proteins

open access: yesFEBS Open Bio, 2023
The intestinal epithelium is a single‐cell layer on the mucosal surface that absorbs food‐derived nutrients and functions as a barrier that protects mucosal integrity.
Ha‐Young Park, Jin‐Hee Yu
doaj   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira   +8 more
wiley   +1 more source

The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation

open access: yesScientific Reports, 2017
We found that hesperidin, a plant-derived bioflavonoid, may be a candidate agent for neuroprotective treatment in the retina, after screening 41 materials for anti-oxidative properties in a primary retinal cell culture under oxidative stress.
Shigeto Maekawa   +12 more
doaj   +1 more source

Ueber Hesperidin [PDF]

open access: yesArchiv der Pharmazie
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openaire   +2 more sources

Biomimetic MCC950‐loaded cerium‐layered double hydroxide nanoparticles for targeted treatment of Type 1 diabetes in streptozotocin‐induced mice

open access: yesBritish Journal of Pharmacology, EarlyView.
The CLMBM nanoparticle (NP) system demonstrates strong and targeted anti‐ROS, antiapoptotic and anti‐inflammatory properties within the pancreas, thereby inhibiting the onset and progression of type 1 diabetes. Background and Purpose The destruction of β‐cells in type 1 diabetes is driven by signalling cascades that ultimately lead to cell apoptosis ...
Huiwen Pang   +9 more
wiley   +1 more source

Hesperidin: A Therapeutic Agent For Obesity.

open access: yesDrug design, development and therapy, 2019
Obesity is a chronic metabolic disease caused by multiple factors and is considered to be a risk factor for type 2 diabetes, cardiovascular disease, hypertension, stroke and various cancers. Hesperidin, a flavanone glycoside, is a natural phenolic compound with a wide range of biological effects.
Xiong,Haijun   +9 more
openaire   +4 more sources

A Narrative Review of Candidate Biomarkers of Total Fruit and Vegetable Intake

open access: yesNutrition Bulletin, EarlyView.
ABSTRACT While an abundance of cohort studies has suggested that greater consumption of fruits and vegetables (FVs) is associated with reduced risk of chronic diseases, current self‐report based dietary assessment tools are susceptible to biases that can reduce their accuracy in estimating dietary intakes, and consequently, the risk estimates obtained ...
Matthew P. Madore   +7 more
wiley   +1 more source

Inactivation of Escherichia coli ATCC 25922 and Saccharomyces cerevisiae IMR-R-L 962 in grapefruit [Citrus paradisi (Macf.)] juice by UV-C light: changes in bioactive compounds and quality characteristics [PDF]

open access: yes, 2018
The viability of UV-C treatment (0.0-2.36 J/cm²) at 254 nm as a non-thermal preservation process for grapefruit juice on microbial inactivation, the organic acids and individual flavonoids, as well as the quality characteristics (pH, ºBrix, titratable ...
la Cava, Enzo Luciano Marcelo   +1 more
core  

Advances in Eco‐Friendly Extraction of Fruit Bioactive Compounds: Technologies, Challenges and Future Directions

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
Fruit bioactive compounds offer antioxidant, anti‐inflammatory, and preventive benefits, yet extraction is hindered by poor solubility and conventional methods using toxic solvents and high energy. This review evaluates traditional and advanced eco‐friendly technologies, highlighting efficiency, selectivity, and sustainability.
Abadi Gebreyesus Hndeya   +2 more
wiley   +1 more source

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