Results 21 to 30 of about 14,554 (194)

Pretreatment of citrus by-products affects polyphenol recovery:a review [PDF]

, 2018
A large amount of citrus waste is generated annually. This waste is of great economic worth, since it contains high levels of polyphenols, which have attracted scientific interest due to their potent antimicrobial and antiradical activities. Pretreatment
Bowyer, Michael C., Golding, John B., Hasperué, Joaquín H., Papoutsis, Konstantinos, Pristijono, Penta, Scarlett, Christopher J., Stathopoulos, Costas E., Vuong, Quan V.   +7 more
core   +2 more sources

Effect of Hesperidin with and without a Calcium (Calcilock®) Supplement on Bone Health in Postmenopausal Women [PDF]

, 2016
Context: Citrus fruits contain unique flavanones. One of the most abundant of the flavanones, hesperidin, has been shown to prevent bone loss in ovariectomized rats. Objective: The objective of the study was to measure the effect of hesperidin with or
Horcajada, Marie Noelle, Jackson, George S., Martin, Berdine R., McCabe, George P., McCabe, Linda, Offord-Cavin, Elizabeth, Peacock, Munro, Weaver, Connie M.   +7 more
core   +1 more source

Recovery of pure Hesperidin from Iraqi Sweet Oranges Peel and study the effect in some bacteria

مجلة بغداد للعلوم, 2014
Citrus fruit contain variety of flavonoids such as Hesperidin (the principal flavonoid in oranges and grapefruit). Hesperidin is found in high concentration in fruit peel of oranges and in substantially lower concentration in juice of these fruits ...
Baghdad Science Journal
doaj   +1 more source

Hesperidin Interacts With CREB-BDNF Signaling Pathway to Suppress Pentylenetetrazole-Induced Convulsions in Zebrafish

Frontiers in Pharmacology, 2021
Hesperidin (3,5,7-trihydroxyflavanone 7-rhamnoglucoside) is a β-7-rutinoside of hesperetin (4′-methoxy-3′,5,7-trihydroxyflavanone), abundantly found in citrus fruits and known to interact with various cellular pathways to show a variety of ...
Pallavi Sharma, Pallavi Sharma, Savita Kumari, Savita Kumari, Jatin Sharma, Rituraj Purohit, Rituraj Purohit, Damanpreet Singh, Damanpreet Singh   +8 more
doaj   +1 more source

Influence of hesperidin on the systemic and intestinal rat immune response [PDF]

, 2018
Polyphenols, widely found in edible plants, influence the immune system. Nevertheless, the immunomodulatory properties of hesperidin, the predominant flavanone in oranges, have not been deeply studied.
Camps i Bossacoma, Mariona, Castell, Margarida, Franch i Masferrer, Àngels, Pérez-Cano, Francisco J.   +3 more
core   +1 more source

Targeting Aurora Kinases as Essential Cell‐Cycle Regulators to Deliver Multi‐Stage Antimalarials Against Plasmodium Falciparum

Angewandte Chemie, EarlyView.
In this study, we repurposed human Aurora kinase‐specific inhibitors to identify potential antimalarial agents. Two inhibitors, hesperadin and TAE684, exhibited sub‐micromolar activity across multiple parasite stages, with hesperadin demonstrating significant potency and selectivity by specifically targeting PfArk1.
Henrico Langeveld, Keletso Maepa, Marché Maree, Jessica L. Thibaud, Nicolaas Salomane, Rosie Bridgwater, Mufuliat T. Famodimu, Luiz C. Godoy, Charisse Flerida A. Pasaje, Nonlawat Boonyalai, Mariana Laureano de Souza, Justin Fong, Tayla Rabie, Mariëtte van der Watt, Rensu P. Theart, Sonja Ghidelli‐Disse, Jacquin C. Niles, Marcus C. S. Lee, Elizabeth A. Winzeler, Michael J. Delves, Kelly Chibale, Kathryn J. Wicht, Lauren B. Coulson, Lyn‐Marié Birkholtz   +23 more
wiley   +2 more sources

Hesperidin and Capsaicin, But Not The Combination, Prevent Hepatic Steatosis and Other Metabolic Syndrome-Related Alterations in Western Diet-Fed Rats [PDF]

, 2018
We aimed to assess the potential effects of hesperidin and capsaicin, independently and in combination, to prevent the development of obesity and its related metabolic alterations in rats fed an obesogenic diet.
Andrea Mosqueda-Solís, Andreu Palou, Bárbara Reynés, Catalina Picó, Juana Sánchez, Mariona Palou, María P. Portillo   +6 more
core   +3 more sources

Migraine susceptibility is modulated by food triggers and analgesic overuse via sulfotransferase inhibition

The Journal of Headache and Pain, 2022
Background/aim Certain constituents in migraine food triggers and non-steroidal anti-inflammatory drugs (NSAIDs) inhibit sulfotransferases (SULTs) that detoxify drugs/chemicals and play role in the metabolism of neurotransmitters.
Doga Vuralli, Burak Arslan, Elif Topa, Andreia Lopes de Morais, Ozlem Gulbahar, Cenk Ayata, Hayrunnisa Bolay   +6 more
doaj   +1 more source

Hesperidin prevents lipopolysaccharide-induced endotoxicity in rats [PDF]

, 2016
Context: Lipopolysaccharide (LPS) is a major trigger of septic shock resulting in multiple organ damage through excessive stimulation of the host’s immune cells resulting in the release of cytokines.
Adelani, Isaacson, Bankole, G.E., Rotimi, Oluwakemi A, Rotimi, S. O   +3 more
core   +1 more source

Hesperidin abrogates bisphenol A endocrine disruption through binding with fibroblast growth factor 21 (FGF-21), α-amylase and α-glucosidase: an in silico molecular study

Journal of Genetic Engineering and Biotechnology, 2022
Background Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations. Bisphenol A (BPA) is an environmental toxicant known to cause endocrine dysregulations.
P. M. Aja, J. N. Awoke, P. C. Agu, A. E. Adegboyega, E. M. Ezeh, I. O. Igwenyi, O. U. Orji, O. G. Ani, B. A. Ale, U. A. Ibiam   +9 more
doaj   +1 more source