Residues from Garcinia humilis were used to obtain a phenolic‐rich extract (GHRE) and incorporated into collagen–starch films. The addition of GHRE improved antioxidant activity, thermal stability and elasticity, while reducing water vapour permeability.
Érica da Costa Monção +7 more
wiley +1 more source
Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice
Hesperidin, a well-known flavanone glycoside mostly found in citrus fruits, showed neuroprotective and antidepressant activity. Agomelatine, a melatonergic MT1/MT2 agonist and 5-HT2C receptor antagonist, exhibits good antidepressant efficacy.
Jegan Sakthivel Nadar +4 more
doaj +1 more source
Intravitreal Kinetics of Hesperidin, Hesperetin, and Hesperidin G: Effect of Dose and Physicochemical Properties [PDF]
Hesperidin, a flavanone glycoside, and its aglycone hesperetin are potential candidates for the treatment of diabetic retinopathy and macular edema. The objective of this study was to delineate vitreal pharmacokinetics of hesperidin and hesperetin and the hydrophilic derivative glucosyl hesperidin (hesperidin G) following intravitreal administration in
Ramesh, Srirangam +2 more
openaire +2 more sources
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira +8 more
wiley +1 more source
Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima +11 more
wiley +1 more source
Inactivation of Escherichia coli ATCC 25922 and Saccharomyces cerevisiae IMR-R-L 962 in grapefruit [Citrus paradisi (Macf.)] juice by UV-C light: changes in bioactive compounds and quality characteristics [PDF]
The viability of UV-C treatment (0.0-2.36 J/cm²) at 254 nm as a non-thermal preservation process for grapefruit juice on microbial inactivation, the organic acids and individual flavonoids, as well as the quality characteristics (pH, ºBrix, titratable ...
la Cava, Enzo Luciano Marcelo +1 more
core
Hesperidin Supplementation Enhances Neuroprotection by Modulating the ERK/MAPK Pathway and Tau Immunoreactivity in an AlCl3‐Induced Cognitive Impairment Model Using Wistar Mice [PDF]
Oria R, Ben R, Tangban C.
europepmc +3 more sources
ABSTRACT Diosmin is often used as a dietary supplement, and it is sometimes used to make phlebotropic drugs for venous diseases. Traditionally, diosmin is obtained by the dehydrogenation of the flavanone glycoside hesperidin through chemical semisynthesis.
Qianle Zhang +5 more
wiley +1 more source
Hesperidin, a natural compound, suppresses the epithelial-to-mesenchymal transition through the TGF-β1/Smad signaling pathway. However, studies on the detailed effects and mechanisms of hesperidin are rare.
Zhouxin Ren +5 more
doaj +1 more source
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley +1 more source

