Results 81 to 90 of about 13,605 (197)

Flavonoids as Anxiolytics in Animal Tests: Systematic Review, Meta‐Analysis, and Bibliometrical Analysis

open access: yesPhytotherapy Research, Volume 40, Issue 1, Page 77-99, January 2026.
ABSTRACT Flavonoids are natural secondary metabolites of plants with a basic composition derived from polyphenols that can produce a plethora of different neurophysiological effects, some of which are relevant to anxiety disorders. As such, many flavonoids have been evaluated in behavioral screens in preclinical research on anxiolytics.
Jhennify Albuquerque Machado   +7 more
wiley   +1 more source

Animal Models and Treatment of Pulmonary Fibrosis: Pharmacogenetic and Nonpharmacogenetic

open access: yesInternational Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Pulmonary fibrosis is a significant lung injury caused by multiple factors that profoundly affect the human quality of life. Currently, various animal models are used to understand the aetiology of pulmonary fibrosis and develop treatments. However, only pharmacogenetic models of pulmonary fibrosis have been discussed, and there have been no reviews of
Xingyu Fang   +7 more
wiley   +1 more source

Beneficial Effects of Clitoria ternatea Flower and Citrus limon Fruit Beverage on Nutritional Status, Lipid Profile, and Adipokine Parameters on Male Rats With Obesity

open access: yesJournal of Obesity, Volume 2026, Issue 1, 2026.
Background Butterfly pea flowers (Clitoria ternatea L.) and lemon fruits (Citrus limon) are rich in phytochemicals and have shown potential anti‐obesity effects. However, the combination of these two medicinal plants as an herbal beverage has not been extensively studied. Objective This study aimed to evaluate the effects of an herbal beverage composed
Fista Utami   +3 more
wiley   +1 more source

Role of hesperidin in modulating antioxidant enzymes in the brain of rats exposed to Nickel Chloride

open access: yesPhytomedicine Plus
Background: This study aimed to investigate the effects of hesperidin on the gene expression of antioxidant enzymes catalase (Cat), superoxide dismutase (Sod), and glutathione peroxidase (Gpx) in the brain and their enzymatic activities in the brain and ...
Niloufar Alizadeh   +2 more
doaj   +1 more source

New insights into therapeutic applications and nanoformulation approaches of hesperidin: An updated review

open access: yesPharmacological Research - Modern Chinese Medicine
Introduction: Hesperidin is a flavanone glycoside occurring in high levels in citrus species. It is among the most significant natural anti-oxidants employed often in pharmaceuticals for therapeutic applications due to its preventive characteristics ...
Keshav Bansal   +3 more
doaj   +1 more source

Hesperidin, a citrus flavonoid, increases the bioavailability of micronutrients of Gallus domesticus (chicken) eggshell: in vitro study

open access: yesChemical Speciation & Bioavailability, 2016
The consumption of citrus flavonoid, hesperidin may inhibit the bone loss. The purpose of this study was to evaluate the effect of hesperidin on the bioavailability of Ca, a probable reason to prevent bone loss.
Sobia Siddique   +4 more
doaj   +1 more source

Chitosan/Hesperidin Nanoparticles for Sufficient, Compatible, Antioxidant, and Antitumor Drug Delivery Systems

open access: yesPharmaceuticals
One flavonoid glycoside with demonstrated therapeutic potential for several illnesses, including cancer, is hesperidin. However, because of its limited bioavailability and solubility, it is only marginally absorbed, necessitating a delivery mechanism to ...
May Almukainzi   +3 more
doaj   +1 more source

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