Results 81 to 90 of about 21,896 (228)

The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation

Scientific Reports, 2017
We found that hesperidin, a plant-derived bioflavonoid, may be a candidate agent for neuroprotective treatment in the retina, after screening 41 materials for anti-oxidative properties in a primary retinal cell culture under oxidative stress.
Shigeto Maekawa, Kota Sato, Kosuke Fujita, Reiko Daigaku, Hiroshi Tawarayama, Namie Murayama, Satoru Moritoh, Takeshi Yabana, Yukihiro Shiga, Kazuko Omodaka, Kazuichi Maruyama, Koji M. Nishiguchi, Toru Nakazawa   +12 more
doaj   +1 more source

Ceramide generation as a novel biological mechanism for chemo-preventive and cytotoxic effects of hesperidin on HT-144 melanoma cells

Beni-Suef University Journal of Basic and Applied Sciences, 2018
Introduction: Hesperidin and its aglycone, hesperetin are abundant natural flavonoid in Citrus and known for their anti-neoplastic and pro-apoptotic properties.
Mahdi Mashhadi Akbar Boojar, Masoud Mashhadi Akbar Boojar, Sepide Golmohammad, Mojtaba Nikkhah Yazdi   +3 more
doaj   +1 more source

Valorization of Banana Biomass: Nutritional and Phytochemical Insights With Applications in Food and Allied Industries

eFood, Volume 7, Issue 2, April 2026.
Composition, biological activity and food application of banana biomass. ABSTRACT The global banana processing industry generates substantial organic waste in the form of peels, leaves, stems, and flowers, posing both environmental challenges and opportunities for valorization within a circular economy framework.
Bushra Iram Fatima, Saeed Akhtar, Muhammad Zulqarnain Khan, Muhammad Qamar, Tariq Ismail, Wisha Saeed, Elham Assadpour, Tuba Esatbeyoglu, Seid Mahdi Jafari   +8 more
wiley   +1 more source

Toward Sustainability in Cardiac Tissue Engineering: Electrospun Polyurethane Scaffolds Functionalized With Lemon‐Derived Bioactives

Global Challenges, Volume 10, Issue 4, April 2026.
Electrospun polyurethane scaffolds biofunctionalized with lemon extract exhibit refined nanofibre morphology, enhanced hydrophilicity, improved mechanical strength, and superior hemocompatibility. The PU/lemon scaffold demonstrates antimicrobial activity and increased fibroblast proliferation, highlighting its potential as a sustainable multifunctional
Mohan Prasath Mani, Saravana Kumar Jaganathan   +1 more
wiley   +1 more source

Identification of plasma and urinary metabolites and catabolites derived from orange juice (poly)phenols: analysis by high-performance liquid chromatography–high-resolution mass spectrometry [PDF]

, 2016
Orange juice is a rich source of (poly)phenols, in particular, the flavanones hesperetin-7-O-rutinoside and naringenin-7-O-rutinoside. Following the acute consumption of 500 mL of orange juice containing 398 μmol of (poly)phenols by 12 volunteers, 0–24 h
Ada García, Alan Crozier, Dalia Malkova, Gee J. M., Gema Pereira-Caro, Hengstmann J. H., Iziar A. Ludwig, José Manuel Moreno-Rojas, McCullough M. L., Palli D., Thelma Polyviou   +10 more
core   +1 more source

Fortifikasi Ekstrak Kulit Jeruk Bali Pada Susu Tinggi Kalsium: Terobosan Baru Dalam Pengatasan Osteoporosis Pada Wanita Menopause, Teruji in Vivo Dan Molecular Docking [PDF]

, 2013
Osteoporosis has one of the cause is lack of estrogen hormone. Commonly prevention therapy is by consuming high calcium milk, but it is not effective. Bali orange's peel (Citrus maxima Merr.) is a waste material but contains phytoestrogen according to ...
Dianingati, R. S. (Ragil), Hana, A. K. (Amanita), Muntafi’ah, L. (Laeli), Novarina, A. (Annisa)   +3 more
core  

Optimizing a sustainable ultrasound assisted extraction method for the recovery of polyphenols from lemon by-products:comparison with hot water and organic solvent extractions [PDF]

, 2018
Response surface methodology (RSM) based on a three-factor and three-level Box–Behnken design was employed for optimizing the aqueous ultrasound-assisted extraction (AUAE) conditions, including extraction time (35–45 min), extraction temperature (45–55 ...
Bowyer, Michael C., Golding, John B., Papoutsis, Konstantinos, Pristijono, Penta, Scarlett, Christopher J., Stathopoulos, Costas E., Vuong, Quan V.   +6 more
core   +2 more sources

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, Volume 15, Issue 4, April 2026.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source

In Vitro Evaluation of Cytotoxic and Pro-Apoptotic Effects of Hesperidin Alone and in Combination with Cisplatin on Human Malignant Melanoma Cell Line (A431)

Pharmaceuticals
Background/Objectives: Melanoma is an aggressive skin cancer with high metastatic potential and poor prognosis in advanced stages. Hesperidin, a natural flavonoid, has shown anticancer properties across various malignancies.
Mehmet Uğur Karabat, Mehmet Cudi Tuncer, İlhan Özdemir   +2 more
doaj   +1 more source

Onosma armenum Extract Loaded Mesoporous Silica Nanoparticles for the Prevention of Biofilm‐Associated Infections

ChemistryOpen, Volume 15, Issue 4, April 2026.
Bioactive mesoporous silica nanoparticles (MSNPs) loaded with O. armenum extract were developed to evaluate their antibiofilm activity against biofilm‐forming Staphylococcus aureus ATCC 25923. The phytochemical content of the extract was analyzed via liquid chromatography–electrospray ionization tandem mass spectrometry.
Sevim Feyza Erdoğmuş, Nilay Isitez, Emre Burak Ertuş, Cengiz Sarikurkcu   +3 more
wiley   +1 more source