Results 11 to 20 of about 124,493 (360)

Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance

open access: yesNature Communications, 2021
Heterochromatin is a critical chromatin compartment, whose integrity governs genome stability and cell fate transitions. How heterochromatin features, including higher-order chromatin folding and histone modifications associated with transcriptional ...
A. Fortuny   +6 more
semanticscholar   +2 more sources

Heterochromatin in plant meiosis

open access: yesNucleus
Heterochromatin is an organizational property of eukaryotic chromosomes, characterized by extensive DNA and histone modifications, that is associated with the silencing of transposable elements and repetitive sequences. Maintaining heterochromatin is crucial for ensuring genomic integrity and stability during the cell cycle.
Cong Wang   +3 more
openaire   +4 more sources

Heterochromatin as an Important Driver of Genome Organization

open access: yesFrontiers in Cell and Developmental Biology, 2020
Heterochromatin is a constituent of eukaryotic genomes with functions spanning from gene expression silencing to constraining DNA replication and repair.
Andrés Pénagos-Puig, M. Furlan-Magaril
semanticscholar   +3 more sources

The regional sequestration of heterochromatin structural proteins is critical to form and maintain silent chromatin

open access: yesEpigenetics & Chromatin, 2022
Budding yeast Saccharomyces cerevisiae and fission yeast Schizosaccharomyces pombe are good models for heterochromatin study. In S. pombe, H3K9 methylation and Swi6, an ortholog of mammalian HP1, lead to heterochromatin formation. However, S.
Junsoo Oh   +3 more
doaj   +1 more source

Global regulation of heterochromatin spreading by Leo1 [PDF]

open access: yesOpen Biology, 2015
Heterochromatin plays important roles in eukaryotic genome regulation. However, the repressive nature of heterochromatin combined with its propensity to self-propagate necessitates robust mechanisms to contain heterochromatin within defined boundaries ...
Laure Verrier   +6 more
doaj   +1 more source

Constitutive Heterochromatin in Eukaryotic Genomes: A Mine of Transposable Elements

open access: yesCells, 2022
Transposable elements (TEs) are abundant components of constitutive heterochromatin of the most diverse evolutionarily distant organisms. TEs enrichment in constitutive heterochromatin was originally described in the model organism Drosophila ...
René Massimiliano Marsano   +1 more
doaj   +1 more source

Different behaviour of C-banded peri-centromeric heterochromatin between sex chromosomes and autosomes in Polyphagan beetles [PDF]

open access: yesComparative Cytogenetics, 2019
Heterochromatin variation was studied after C-banding of male karyotypes with a XY sex formula from 224 species belonging to most of the main families of Coleoptera.
Anne-Marie Dutrillaux   +1 more
doaj   +3 more sources

The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast. [PDF]

open access: yesPLoS Genetics, 2014
Heterochromatin preferentially assembles at repetitive DNA elements, playing roles in transcriptional silencing, recombination suppression, and chromosome segregation.
Scott P Kallgren   +8 more
doaj   +1 more source

Maternal depletion of Piwi, a component of the RNAi system, impacts heterochromatin formation in Drosophila. [PDF]

open access: yesPLoS Genetics, 2013
A persistent question in epigenetics is how heterochromatin is targeted for assembly at specific domains, and how that chromatin state is faithfully transmitted.
Tingting Gu, Sarah C R Elgin
doaj   +1 more source

DNA Double-Strand Break Repair: All Roads Lead to HeterochROMAtin Marks

open access: yesFrontiers in Genetics, 2021
In response to DNA double-strand breaks (DSBs), chromatin modifications orchestrate DNA repair pathways thus safeguarding genome integrity. Recent studies have uncovered a key role for heterochromatin marks and associated factors in shaping DSB repair ...
Pierre Caron   +2 more
doaj   +1 more source

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