Results 41 to 50 of about 75,754 (257)

Variation in telomeric heterochromatin in somaclones of rye [PDF]

, 1992
Somaclonal variation in telomeric heterochromatin was detected by in situ hybridization with the het 1 probe, which hybridizes to a 380-bp repeated sequence family. In a control cultivar, Gazelle, large blocks of signal were detected at the telomeres but
Kaltsikes, P. J., S. H. Steele, P. J. Bebeli, Owen, P. G., Steele, S. H., Bebeli, P. J., P. J. Kaltsikes, A. Karp, Karp, A., P. G. Owen   +9 more
core   +1 more source

Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance

Nature Communications, 2021
The heterochromatin compartment is key for genome stability and cell fate transitions. Here, by tracking the heterochromatin response to UV damage in real time, the authors reveal how heterochromatin features are preserved following a genotoxic stress ...
Anna Fortuny, Audrey Chansard, Pierre Caron, Odile Chevallier, Olivier Leroy, Olivier Renaud, Sophie E. Polo   +6 more
doaj   +1 more source

Drosophila HP1c is regulated by an auto-regulatory feedback loop through its binding partner Woc [PDF]

, 2009
HP1 is a major component of chromatin and regulates gene expression through its binding to methylated histone H3. Most eukaryotes express at least three isoforms of HP1 with similar domain architecture.
Eskeland, Ragnhild, RAFFA, GRAZIA DANIELA, Eskeland Ragnhild, Abel, Jochen, Jochen Abel, Raffa Grazia D., Raffa, Grazia D, Ragnhild Eskeland, Abel Jochen, Kremmer Elisabeth, Abel, J., Imhof Axel, Raffa, G.D., Ragnhild Eskel, Imhof, Axel, Eskeland, R., Grazia D. Raffa, Kremmer, E., Imhof, A., Kremmer, Elisabeth, Axel Imhof, Grazia D Raffa, Elisabeth Kremmer   +22 more
core   +1 more source

Patterns of Heterochromatin Transitions Linked to Changes in the Expression of Plasmodium falciparum Clonally Variant Genes

Microbiology Spectrum, 2023
The survival of malaria parasites in the changing human blood environment largely depends on their ability to alter gene expression by epigenetic mechanisms.
Lucas Michel-Todó, Cristina Bancells, Núria Casas-Vila, Núria Rovira-Graells, Carles Hernández-Ferrer, Juan R. González, Alfred Cortés   +6 more
doaj   +1 more source

How HP1 Post-Translational Modifications Regulate Heterochromatin Formation and Maintenance

Cells, 2020
Heterochromatin Protein 1 (HP1) is a highly conserved protein that has been used as a classic marker for heterochromatin. HP1 binds to di- and tri-methylated histone H3K9 and regulates heterochromatin formation, functions and structure.
Raquel Sales-Gil, Paola Vagnarelli
doaj   +1 more source

Heterochromatin as an Important Driver of Genome Organization

Frontiers in Cell and Developmental Biology, 2020
Heterochromatin is a constituent of eukaryotic genomes with functions spanning from gene expression silencing to constraining DNA replication and repair.
Andrés Penagos-Puig, Mayra Furlan-Magaril   +1 more
doaj   +1 more source

The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly.

PLoS Genetics, 2022
The epigenetic landscape of a cell frequently changes in response to fluctuations in nutrient levels, but the mechanistic link is not well understood.
Kehan Bao, Chun-Min Shan, Xiao Chen, Gulzhan Raiymbek, Jeremy G Monroe, Yimeng Fang, Takenori Toda, Kristin S Koutmou, Kaushik Ragunathan, Chao Lu, Luke E Berchowitz, Songtao Jia   +11 more
doaj   +1 more source

Imaging the Response to DNA Damage in Heterochromatin Domains

Frontiers in Cell and Developmental Biology, 2022
The eukaryotic genome is assembled in a nucleoprotein complex called chromatin, whose organization markedly influences the repair of DNA lesions. For instance, compact chromatin states, broadly categorized as heterochromatin, present a challenging ...
Audrey Chansard, Enrico Pobega, Pierre Caron, Sophie E. Polo   +3 more
doaj   +1 more source

Cbx2 targets PRC1 to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner [PDF]

, 2015
Polycomb repressive complexes PRC1 and PRC2 regulate expression of genes involved in proliferation and development. In mouse early embryos, however, canonical PRC1 localizes to paternal pericentric heterochromatin (pat-PCH), where it represses ...
Duan, Shili, Albert, Mareike, Peters, Antoine H. F. M., Kaustov, Lilia, Liu, Zichuan, Brykczynska, Urszula, Arrowsmith, Cheryl H., Tardat, Mathieu, Kunzmann, Rico, Thierry, Raphael   +9 more
core   +1 more source

Phase transitions in heterochromatin organization [PDF]

, 2023
International audienceHeterochromatin formation has been proposed to involve phase transitions on the level of the three-dimensional folding of heterochromatin regions and the liquid-liquid demixing of heterochromatin proteins.
Fabian Erdel, Erdel, Fabian
core   +1 more source