Results 31 to 40 of about 110,529 (257)

Transcription of satellite DNAs in insects [PDF]

open access: yes, 2011
Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species.
D. Ugarkovic   +3 more
core   +1 more source

Negative Regulators of an RNAi-Heterochromatin Positive Feedback Loop Safeguard Somatic Genome Integrity in Tetrahymena

open access: yesCell Reports, 2017
RNAi-mediated positive feedback loops are pivotal for the maintenance of heterochromatin, but how they are downregulated at heterochromatin-euchromatin borders is not well understood.
Jan H. Suhren   +5 more
doaj   +1 more source

Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation

open access: yesCell Reports, 2020
Summary: Heterochromatin functions as a scaffold for factors responsible for gene silencing and chromosome segregation. Heterochromatin can be assembled by multiple pathways, including RNAi and RNA surveillance.
Si Young Lee   +8 more
doaj   +1 more source

Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis. [PDF]

open access: yesPLoS Genetics, 2012
Organismal aging is influenced by a multitude of intrinsic and extrinsic factors, and heterochromatin loss has been proposed to be one of the causes of aging. However, the role of heterochromatin in animal aging has been controversial.
Kimberly Larson   +8 more
doaj   +1 more source

Karyotypic variation in the Andean rodent Phyllotis xanthopygus (Waterhouse, 1837) (Rodentia, Cricetidae, Sigmodontinae) [PDF]

open access: yes, 2014
Phyllotis xanthopygus (Waterhouse, 1837) is an Andean rodent endemic to South America. Despite its wide geographical distribution in Argentina, few individuals have been studied on the cytogenetic level and only through conventional staining.
Cuello, Pablo Andrés   +8 more
core   +4 more sources

De Novo Polycomb Recruitment: Lessons from Latent Herpesviruses

open access: yesViruses, 2021
The Human Herpesviruses persist in the form of a latent infection in specialized cell types. During latency, the herpesvirus genomes associate with cellular histone proteins and the viral lytic genes assemble into transcriptionally repressive ...
Sara A. Dochnal   +2 more
doaj   +1 more source

ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing. [PDF]

open access: yes, 2009
Constitutive heterochromatin in Arabidopsis thaliana is marked by repressive chromatin modifications, including DNA methylation, histone H3 dimethylation at Lys9 (H3K9me2) and monomethylation at Lys27 (H3K27me1).
Bernatavichute, Yana V   +9 more
core   +1 more source

Regulation of ectopic heterochromatin-mediated epigenetic diversification by the JmjC family protein Epe1.

open access: yesPLoS Genetics, 2019
H3K9 methylation (H3K9me) is a conserved marker of heterochromatin, a transcriptionally silent chromatin structure. Knowledge of the mechanisms for regulating heterochromatin distribution is limited.
Masato Sorida   +12 more
doaj   +1 more source

Mediator directs co-transcriptional heterochromatin assembly by RNA interference-dependent and -independent pathways. [PDF]

open access: yesPLoS Genetics, 2013
Heterochromatin at the pericentromeric repeats in fission yeast is assembled and spread by an RNAi-dependent mechanism, which is coupled with the transcription of non-coding RNA from the repeats by RNA polymerase II. In addition, Rrp6, a component of the
Eriko Oya   +5 more
doaj   +1 more source

H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization. [PDF]

open access: yes, 2013
Histone lysine (K) methylation has been shown to play a fundamental role in modulating chromatin architecture and regulation of gene expression. Here we report on the identification of histone H3K56, located at the pivotal, nucleosome DNA entry/exit ...
Bussemer, Silva   +9 more
core   +3 more sources

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