The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken [PDF]
, 2005 The replacement histone H2A.Z is variously reported as being linked to gene expression and preventing the spread of heterochromatin in yeast, or concentrated at heterochromatin in mammals.
Bonifer, C. +8 more
core +5 more sources
How HP1 Post-Translational Modifications Regulate Heterochromatin Formation and Maintenance
Cells, 2020 Heterochromatin Protein 1 (HP1) is a highly conserved protein that has been used as a classic marker for heterochromatin. HP1 binds to di- and tri-methylated histone H3K9 and regulates heterochromatin formation, functions and structure.
Raquel Sales-Gil, Paola Vagnarelli
doaj +1 more source
Microbiology Spectrum, 2023 The survival of malaria parasites in the changing human blood environment largely depends on their ability to alter gene expression by epigenetic mechanisms.
Lucas Michel-Todó +6 more
doaj +1 more source
PLoS Biology, 2003 Heterochromatin is usually thought of as a stable and inactive region of the genome.
openaire +5 more sources
The analysis of pendolino (peo) mutants reveals differences in the fusigenic potential among Drosophila telomeres [PDF]
, 2015 Drosophila telomeres are sequence-independent structures that are maintained by transposition to chromosome ends of three specialized retroelements (HeT-A, TART and TAHRE; collectively designated as HTT) rather than telomerase activity. Fly telomeres are
Burla, Romina +8 more
core +3 more sources
The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly.
PLoS Genetics, 2022 The epigenetic landscape of a cell frequently changes in response to fluctuations in nutrient levels, but the mechanistic link is not well understood.
Kehan Bao +11 more
doaj +1 more source
Imaging the Response to DNA Damage in Heterochromatin Domains
Frontiers in Cell and Developmental Biology, 2022 The eukaryotic genome is assembled in a nucleoprotein complex called chromatin, whose organization markedly influences the repair of DNA lesions. For instance, compact chromatin states, broadly categorized as heterochromatin, present a challenging ...
Audrey Chansard +3 more
doaj +1 more source
Karyotype evolution in progress: A new diploid number in Belostoma candidulum (Heteroptera: Belostomatidae) from Argentina leading to new insights into its ecology and evolution [PDF]
, 2014 A novel chromosome complement (2n = 14 = 12 + XY/XX; male/female sex chromosomes), male meiosis behaviour, heterochromatin characterization, and frequency and distribution of chiasmata are described for the first time in specimens from a natural ...
Bressa, Maria Jose +1 more
core +1 more source
The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic
eLife, 2016 Heterochromatin is enriched for specific epigenetic factors including Heterochromatin Protein 1a (HP1a), and is essential for many organismal functions.
Joel M Swenson +4 more
doaj +1 more source
Heterochromatin as an Important Driver of Genome Organization
Frontiers in Cell and Developmental Biology, 2020 Heterochromatin is a constituent of eukaryotic genomes with functions spanning from gene expression silencing to constraining DNA replication and repair.
Andrés Penagos-Puig +1 more
doaj +1 more source