Results 71 to 80 of about 110,529 (257)

Putting the genome on the map [PDF]

, 1998
The maps of our everyday lives are much more than just linear lists of place names. Instead, their colours, symbols, contours and grid lines seek to describe different types of landscape, and to depict the spatial relationships between structural and ...
Andrulis, Baumgartner, Belmont, Bickmore, Blencowe, Boddy, Boy de la Tour, Brett, Bridger, Bridger, Brown, Buchenau, Capco, Carter, Clemson, Craig, Craig, Craig, Cremer, Cross, Csink, Dernburg, Dietzel, Dobie, Eils, Ferguson, Ferreira, Festenstein, Foisner, Fox, Gerdes, Gotta, Heck, Hernandez-Verdun, Hozak, Imai, Jackson, Jackson, Jeppesen, Kill, Krystosek, Kurz, LaSalle, Lawlis, Leitch, Li, Linares-Cruz, Maillet, Marshall, McQueen, Milot, Mortillaro, Nagele, O'Keefe, Paillsson, Paulson, Pombo, Pyrpasopoulou, Razin, Razin, Robinett, Saccone, Sachs, Saitoh, Satijn, Shelby, Taniura, Vourc'h, Weitspolthammer, Ye, Yokota, Zink, Zirbel   +72 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

FISH-aimed karyotype analysis in Aconitum subgen : aconitum reveals excessive rDNA sites in tetraploid taxa [PDF]

, 2018
The location of 5S and 35S rDNA sequences in chromosomes of four Aconitum subsp. Aconitum species was analyzed after fluorescence in situ hybridization (FISH). Both in diploids (2n = 2x = 16; Aconitum variegatum, A. degenii) and tetraploids (2n = 4× = 32;
Grabowska-Joachimiak, Aleksandra, Hasterok, Robert, Joachimiak, Andrzej, Musiał, Krystyna, Sliwinska, Elwira   +4 more
core   +2 more sources

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

The architecture of chicken chromosome territories changes during differentiation [PDF]

, 2004
BACKGROUND: Between cell divisions the chromatin fiber of each chromosome is restricted to a subvolume of the interphase cell nucleus called chromosome territory.
Bonifer, C., Cremer, C., Cremer, T., Dietzel, S., Mayer, R., Schnapp, V., Stadler, S., Stein, S.   +7 more
core   +4 more sources

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

Ring-like distribution of constitutive heterochromatin in bovine senescent cells. [PDF]

PLoS ONE, 2011
BACKGROUND: Cells that reach "Hayflick limit" of proliferation, known as senescent cells, possess a particular type of nuclear architecture. Human senescent cells are characterized by the presence of highly condensed senescent associated heterochromatin ...
Andrey Pichugin, Nathalie Beaujean, Xavier Vignon, Yegor Vassetzky   +3 more
doaj   +1 more source

The Cell Biology of Heterochromatin

Cells, 2022
A conserved feature of virtually all higher eukaryotes is that the centromeres are embedded in heterochromatin. Here we provide evidence that this tight association between pericentric heterochromatin and the centromere is essential for proper metaphase ...
Brandt Warecki, William Sullivan
doaj   +1 more source

Selfish centromeres, selfless heterochromatin

Cell, 2021
Centromeres are specialized regions on chromosomes recruiting a set of proteins required for faithful chromosome segregation. Differences in centromere strength can potentially bias chromosome segregation toward one of the daughter cells during division. Kumon et al. propose a new model of evolutionary impact on the balance of centromere strength.
Nikalayevich, Elvira, Verlhac, Marie-Hélène   +1 more
openaire   +2 more sources

DNA methylation dynamics in aging: How far are we from understanding the mechanisms? [PDF]

, 2018
DNA methylation is currently the most promising molecular marker for monitoring aging and predicting life expectancy. However, the mechanisms underlying age-related DNA methylation changes remain mostly undiscovered.Here we discuss the current knowledge ...
Caiafa, Paola, Ciccarone, Fabio, Tagliatesta, Stefano, Zampieri, Michele   +3 more
core   +1 more source