Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates. [PDF]
, 2017 A series of emissive ribonucleoside purine mimics, all comprised of an isothiazolo[4,3-d]pyrimidine core, was prepared using a divergent pathway involving a key Thorpe-Ziegler cyclization.
Fin, Andrea +2 more
core +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 The two β-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacterium Brucella suis, BsuCA1 and BsuCA2, were investigated for their inhibition profile with a series of pyridine-3-sulphonamide derivatives incorporating 4-hetaryl moieties.
Simona Maria Monti +5 more
doaj +1 more source
Heterocycles from cyclopropenones
RSC Advances, 2022 Great attention has been paid to cyclopropenones as they are present in many natural sources.
Ashraf A. Aly +5 more
openaire +2 more sources
4-Chloro-6-ethoxy-2-(methylthio)pyrimidine
Molbank, 2016 4,6-Dichloro-2-(methylthio)pyrimidine (3) reacts with EtONa in EtOH, at ca. 20 °C, for 2 h, to give exclusively 4-chloro-6-ethoxy-2-(methylthio)pyrimidine (5) in 89% yield. The latter is presented as a useful multifunctionalised pyrimidine scaffold.
Andreas S. Kalogirou +1 more
doaj +1 more source
Aminoazole-Based Diversity-Oriented Synthesis of Heterocycles
Frontiers in Chemistry, 2018 The comprehensive review contains the analysis of literature data concerning reactions of heterocyclization of aminoazoles and demonstrates the application of these types of transformations in diversity-oriented synthesis.
Maryna V. Murlykina +7 more
doaj +1 more source
Fine tuning of MLCT states in new mononuclear complexes of ruthenium(II) containing tris(1-pyrazolyl)methane, 2,2′-bipyridine and aromatic nitrogen heterocycles [PDF]
, 2005 The syntheses of new mononuclear ruthenium(II) complexes of the type: [Ru(bpy)(L)(tpm)](PF6)2 {tpm = tris(1-pyrazolyl)-methane; bpy = 2,2′-bipyridine; L = pz (pyrazine; 1), 4,4′-bpy (4,4′-bipyridine; 2), and bpe [trans-1,2-bis(4-pyridyl)ethylene; 3]} are
Anderson +50 more
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Amine, Amido, and Imido Complexes of Tantalum Supported by a Pyridine-Linked Bis(phenolate) Pincer Ligand: Ta−N π-Bonding Influences Pincer Ligand Geometry [PDF]
, 2009 A series of tantalum imido and amido complexes supported by a pyridine-linked bis(phenolate) ligand has been synthesized. Characterization of these complexes via X-ray crystallography reveals both C_s and C_2 binding modes of the bis(phenolate)pyridine ...
Bercaw, John E. +3 more
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Transformation of (allo)securinine to (allo)norsecurinine via a molecular editing strategy
Frontiers in ChemistrySecurinega alkaloids have intrigued chemists since the isolation of securinine in 1956. This family of natural products comprises a securinane subfamily with a piperidine substructure and norsecurinane alkaloids featuring a pyrrolidine core.
Seoyoung Kim, Hee-Seung Lee, Sunkyu Han
doaj +1 more source
Sodium-mediated magnesiation of thiophene and tetrahydrothiophene : structural contrasts with furan and tetrahydrofuran [PDF]
, 2010 Sulfur-containing heterocycles are currently attracting agreat deal of interest in several diverse fields. For instance, substituted tetrahydrothiophenes have received considerable attention due to their extremely wide-ranging chemical and biological ...
, EPSRC (Funder) +4 more
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Methods for treating bone deficit conditions with benzothiazole [PDF]
, 1999 " Compounds containing two aromatic systems covalently linked through a linker containing one or more atoms, or ""linker"" defined as including a covalent bond per se so as to space the aromatic systems at a distance 1.5-15 .ANG., are effective in ...
Baindur, Nand +6 more
core +1 more source