Results 271 to 280 of about 176,899 (357)

Streamlining SuFEx Inhibitor Development: A Unified Approach Using Photolabile and Orthogonal Sulfinate Protecting Groups

Angewandte Chemie, EarlyView.
This Study outlines the discovery and selection of sulfinate protecting groups (SPGs) based on their overall stability, ease of synthesis, and simple deprotection conditions, including two novel, photolabile SPGs that can be directly converted to the sulfonyl fluoride (SFs) using light and selectfluor.
Twinkle I. Patel, Makayla L. Williams, Yumeng Chi, Ramkrishna Laha, Matthew J. Moschitto   +4 more
wiley   +1 more source

QSAR Modeling and Biological Testing of Some 15-LOX Inhibitors in a Series of Homo- and Heterocyclic Compounds. [PDF]

Molecules
Khairullina V, Martynova Y, Kanevsky M, Kanevskaya I, Zimin Y, Maksimov L.   +5 more
europepmc   +1 more source

Syntheses of Heterocyclic Compounds of Nitrogen. LXXIX

, 1952
Torizo Takahashi, Kenzo Satake
openalex   +2 more sources

Studies in Heterocyclic Compounds. Part III. [PDF]

, 1934
ANUKUL CHANDRA CIRCAR, SUSTHIR CHANDRA SEN   +1 more
openalex   +1 more source

Desulfurizative Fluorination of N‐CF3 Thioformamides for the Efficient Synthesis of N(CF3)(CF2H) Amines with Enhanced Stability

Angewandte Chemie, EarlyView.
We present the first general synthetic strategy for accessing N(CF3)(CF2H) amines, which display a 2000‐fold increase in stability over N‐CF3 amines. The compounds are synthesized through a desulfurization–fluorination of N‐CF3 thioformamides. Abstract With poor metabolic stability being a major cause of failure in drug development, there is a pressing
Gina Wycich, Jaime Ponce‐de‐León, Linhao Liu, Franziska Schoenebeck   +3 more
wiley   +1 more source

Synthesis and PASS-assisted evaluation of new heterocyclic compounds containing hydroquinoline scaffolds. [PDF]

BMC Chem
Manahelohe GM, Shikhaliev KS.
europepmc   +1 more source

Syntheses of Heterocyclic Compounds of Nitrogen. CVI

, 1957
Torizo Takahashi, JUTARO OKADA, Katsumi Koshi   +2 more
openalex   +2 more sources

Cooperative Photometallobiocatalysis: Nonheme Fe Enzyme‐Catalyzed Enantioconvergent Radical Decarboxylative Azidation, Thiocyanation, and Isocyanation of Redox‐Active Esters

Angewandte Chemie, EarlyView.
Through the directed evolution of an underexploited nonheme Fe extradiol dioxygenase, we developed a unified cooperative photobiocatalytic strategy to allow for three types of enantioconvergent radical transformations, including azidation, thiocyanation, and isocyanation.
Liu‐Peng Zhao, Ken Lin, Pei‐Pei Xie, Huichong Liu, Hengye Xiang, Xin Liu, Yunlong Zhao, Peng Liu, Yang Yang   +8 more
wiley   +1 more source

Enzymatic synthesis of pyridine heterocyclic compounds and their thermal stability. [PDF]

Heliyon
Wang L, Zhao Q, Wu G, Wang P, Zhou M, Wu Z, Lai M, Zhao M.   +7 more
europepmc   +1 more source

Syntheses of Heterocyclic Compounds of Nitrogen. LXV

, 1952
Shigeo Senda, Torizo Takahashi
openalex   +2 more sources