Results 11 to 20 of about 1,436,185 (319)

Mitochondrial Heterogeneity [PDF]

open access: yesFrontiers in Genetics, 2019
Cell-to-cell heterogeneity drives a range of (patho)physiologically important phenomena, such as cell fate and chemotherapeutic resistance. The role of metabolism, and particularly mitochondria, is increasingly being recognised as an important explanatory factor in cell-to-cell heterogeneity.
Juvid Aryaman   +6 more
openaire   +6 more sources

Heterogeneous Agglomeration [PDF]

open access: yesReview of Economics and Statistics, 2017
Many prior treatments of agglomeration explicitly or implicitly assume that all industries agglomerate for the same reasons. This paper uses UK establishment-level coagglomeration data to document substantial heterogeneity across industries in the microfoundations of agglomeration economies.
Faggio, Giulia   +2 more
openaire   +6 more sources

Heterogeneous convergence [PDF]

open access: yesEconomics Letters, 2007
We use US county-level data to estimate convergence rates for 22 individual states. We find significant heterogeneity. E.g., the California estimate is 19.9% and the New York estimate is 3.3%. Convergence rates are essentially uncorrelated with income levels.
Young, Andrew   +2 more
openaire   +11 more sources

Macrophage Heterogeneity [PDF]

open access: yesVox Sanguinis, 1979
Abstract. Macrophages are a mobile, functionally diverse group of cells which may be recruited and stimulated to a high degree of metabolic activity. Heterogeneity may be detected from one site to another and result from local influences, e.g. lung v.
K E, Hopper, P R, Wood, D S, Nelson
openaire   +2 more sources

TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?

open access: yesMembranes, 2023
Breast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly ...
Mayar Soussi   +2 more
doaj   +1 more source

Chemotherapy Associated Ovarian Failure

open access: yesFrontiers in Endocrinology, 2020
As the incidence of malignancies in young adults is increasing, fertility preservation in cancer survivors arises as a major concern. Especially among female cancer patients, pregnancy rates are estimated to be 40% lower compared to women of the same age.
Davide Mauri   +10 more
doaj   +1 more source

Extranodal diffuse large B-cell lymphomas: A retrospective case series and review of the literature

open access: yesHematology Reports, 2018
Non-Hodgkin lymphomas commonly show extranodal involvement (25-30%) but primary diffuse large B-cell lymphomas(DLBCL) with extranodal localization represent clinically and molecularly distinct entities.
Stergios Boussios   +8 more
doaj   +1 more source

Measurement of Protein-Protein Interactions through Microscale Thermophoresis (MST)

open access: yesBio-Protocol, 2020
The binding interactions of PD-1 and PD-L1 have been studied by surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) over the past few years, but these investigations resulted in controversy regarding the values of the dissociation ...
Magnez Romain   +4 more
doaj   +1 more source

Analyses of natural courses of Japanese patients with Alzheimer's disease using placebo data from placebo‐controlled, randomized clinical trials: Japanese Study on the Estimation of Clinical course of Alzheimer's disease

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2019
Introduction Symptomatic anti‐Alzheimer's disease (AD) drugs have been commonly used for the treatment of AD. Knowing the natural courses of patients with AD on placebo is highly relevant for clinicians to understand their efficacy and for investigators ...
Mitsunori Watanabe   +15 more
doaj   +1 more source

Influence of EGF and pro-NGF on EGFR/SORTILIN interaction and clinical impact in head and neck squamous cell carcinoma

open access: yesFrontiers in Oncology, 2023
Head and Neck Squamous Cell Carcinoma (HNSCC) remains a cancer with a poor prognosis, with a 5-year survival rate of less than 50%. Although epidermal growth factor receptor (EGFR) is almost always overexpressed, targeted anti-EGFR therapies have modest ...
Martin Morisse   +13 more
doaj   +1 more source

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