Results 31 to 40 of about 3,184,162 (305)
Head and Neck Squamous Cell Carcinoma (HNSCC) remains a cancer with a poor prognosis, with a 5-year survival rate of less than 50%. Although epidermal growth factor receptor (EGFR) is almost always overexpressed, targeted anti-EGFR therapies have modest ...
Martin Morisse +13 more
doaj +1 more source
Generalized voter-like models on heterogeneous networks [PDF]
We describe a generalization of the voter model on complex networks that encompasses different sources of degree-related heterogeneity and that is amenable to direct analytical solution by applying the standard methods of heterogeneous mean-field theory.
Baronchelli, Andrea +3 more
core +2 more sources
Heterogeneous Agents Situated in Heterogeneous Spaces
This paper introduces the Multi-layered Multi-Agent Situated System model (MMASS), a model for Multi-Agent Systems (MAS) situated in an environment. The main feature of the MMASS model is to give an explicit definition of the spatial structure of the environment in which the system of situated agents are acting and interacting.
BANDINI, STEFANIA +2 more
openaire +3 more sources
Metabolism of pancreatic neuroendocrine tumors: what can omics tell us?
IntroductionReprogramming of cellular metabolism is now a hallmark of tumorigenesis. In recent years, research on pancreatic neuroendocrine tumors (pNETs) has focused on genetic and epigenetic modifications and related signaling pathways, but few studies
Arnaud Jannin +8 more
doaj +1 more source
Relative Humidity as an Indicator for Cloud Formation over Heterogeneous land surfaces [PDF]
The influence of land surface heterogeneity on potential cloud formation is investigated using relative humidity as an indicator. This is done by performing numerical experiments using a large-eddy simulation model (LES).
Heerwaarden, C.C., van +1 more
core +2 more sources
Introduction: The quest for small molecule inhibitors of the PD-1/PD-L1 checkpoint continues in parallel to the extensive development of monoclonal antibodies directed against this immune checkpoint. Drug screening strategies are being set up to identify
Xavier Thuru +3 more
doaj +1 more source
Propagation and Maintenance of Cancer Stem Cells: A Major Influence of the Long Non-Coding RNA H19
Cancer stem cells (CSCs) represent a rare population of tumor cells that exhibit stem cell properties with the abilities of self-renewal and differentiation.
Clément Lecerf +3 more
doaj +1 more source
Flow Cytometry-based Method for Efficient Sorting of Senescent Cells
Cellular senescence is a reprogrammed cell state triggered as an adaptative response to a variety of stresses, most often those affecting the genome integrity.
Erwan Goy +12 more
doaj +1 more source
Heterogeneous convergence [PDF]
We use US county-level data to estimate convergence rates for 22 individual states. We find significant heterogeneity. E.g., the California estimate is 19.9% and the New York estimate is 3.3%. Convergence rates are essentially uncorrelated with income levels.
Young, Andrew +2 more
openaire +11 more sources
Triple negative breast cancer (TNBC) is an aggressive malignancy for which chemotherapy remains the standard treatment. However, between 3 and 5 years after chemotherapy, about half patients will relapse and it is essential to identify vulnerabilities of
Marie Winter +10 more
doaj +1 more source

