Results 31 to 40 of about 2,178,756 (313)

Propagation and Maintenance of Cancer Stem Cells: A Major Influence of the Long Non-Coding RNA H19

Cells, 2020
Cancer stem cells (CSCs) represent a rare population of tumor cells that exhibit stem cell properties with the abilities of self-renewal and differentiation.
Clément Lecerf, Evodie Peperstraete, Xuefen Le Bourhis, Eric Adriaenssens   +3 more
doaj   +1 more source

Flow Cytometry-based Method for Efficient Sorting of Senescent Cells

Bio-Protocol, 2023
Cellular senescence is a reprogrammed cell state triggered as an adaptative response to a variety of stresses, most often those affecting the genome integrity.
Erwan Goy, Nathalie Martin, Claire Drullion, Laure Saas, Olivier Molendi-Coste, Laurent Pineau, David Dombrowicz, Emeric Deruy, Hélène Bauderlique-Leroy, Olivier Samyn, Joe Nassour, Yvan de Launoit, Corinne Abbadie   +12 more
doaj   +1 more source

Hidden allies: how extracellular vesicles drive biofilm formation, stress adaptation, and host–immune interactions in human fungal pathogens

mBio
Pathogenic fungi pose a significant threat to human health, especially given the rising incidence of invasive fungal infections and the emergence of drug-resistant strains.
Philipp Brandt, Rima Singha, Iuliana V. Ene   +2 more
doaj   +1 more source

Mitochondrial adaptation decreases drug sensitivity of persistent triple negative breast cancer cells surviving combinatory and sequential chemotherapy

Neoplasia: An International Journal for Oncology Research, 2023
Triple negative breast cancer (TNBC) is an aggressive malignancy for which chemotherapy remains the standard treatment. However, between 3 and 5 years after chemotherapy, about half patients will relapse and it is essential to identify vulnerabilities of
Marie Winter, Amina Nait Eldjoudi, Catherine Guette, Hubert Hondermarck, Roland P. Bourette, Quentin Fovez, William Laine, Bart Ghesquiere, Eric Adriaenssens, Jérôme Kluza, Xuefen Le Bourhis   +10 more
doaj   +1 more source

Genetic heterogeneity of residual variance in broiler chickens [PDF]

, 2006
Aims were to estimate the extent of genetic heterogeneity in environmental variance. Data comprised 99 535 records of 35-day body weights from broiler chickens reared in a controlled environment.
Rowe Suzanne J, Avendano, Santiago, Hill, William G., White, Ian M. S., White Ian MS, Ian M.S. White, Avendaño Santiago, Hill William G, Suzanne J. Rowe, William G. Hill, Suzanne J Rowe, Ian MS White, William G Hill, Santiago Avendaño, Rowe, Suzanne J.   +14 more
core   +1 more source

Approaches for identifying and measuring heteroresistance in azole-susceptible Candida isolates

Microbiology Spectrum
Heteroresistance to antifungal agents poses a significant challenge in the treatment of fungal infections. Currently, the absence of established methods for detecting and measuring heteroresistance impedes progress in understanding this phenomenon in ...
Cécile Gautier, Eli I. Maciel, Iuliana V. Ene   +2 more
doaj   +1 more source

Polyoxometalate inhibition of SOX2-mediated tamoxifen resistance in breast cancer

Cell Communication and Signaling
Background Increased cancer stem cell (CSC) content and SOX2 overexpression are common features in the development of resistance to therapy in hormone-dependent breast cancer, which remains an important clinical challenge. SOX2 has potential as biomarker
Iskander Aurrekoetxea-Rodriguez, So Young Lee, Miriam Rábano, Isabel Gris-Cárdenas, Virginia Gamboa-Aldecoa, Irantzu Gorroño, Isabella Ramella-Gal, Connor Parry, Robert M. Kypta, Beñat Artetxe, Juan M. Gutierrez-Zorrilla, Maria dM. Vivanco   +11 more
doaj   +1 more source

Biochemical Characterization of a New Oligoalginate Lyase and Its Biotechnological Application in Laminaria japonica Degradation

Frontiers in Microbiology, 2020
Oligoalginate lyases catalyze the degradation of alginate polymers and oligomers into monomers, a prerequisite for biotechnological utilizing alginate.
Shangyong Li, Shangyong Li, Linna Wang, Samil Jung, Beom Suk Lee, Ningning He, Myeong-Sok Lee   +6 more
doaj   +1 more source

Heterogeneity of neuroblastoma [PDF]

Oncoscience, 2015
Neuroblastoma (NB) is the most common pediatric solid tumor and represents 15% of all childhood cancer deaths. High cellular heterogeneity is a hallmark of NB, which may account for the wide range of clinical presentations and non-uniform response to treatment.
openaire   +2 more sources

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source