Results 51 to 60 of about 2,253,886 (314)

Exploring the Role of TRIP-Brs in Human Breast Cancer: An Investigation of Expression, Clinicopathological Significance, and Prognosis

Molecular Therapy: Oncolytics, 2020
TRIP-Brs, a group of transcription factors (TFs) that modulate several mechanisms in higher organisms. However, the novel paradigm to target TRIP-Brs in specific cancer remains to be deciphered.
Raj Kumar Mongre, Chandra Bhushan Mishra, Samil Jung, Beom Suk Lee, Nguyen Thi Ngoc Quynh, Nguyen Hai Anh, Davaajragal Myagmarjav, Taeyeon Jo, Myeong-Sok Lee   +8 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Link-heterogeneity vs. node-heterogeneity in clusters [PDF]

2010 International Conference on High Performance Computing, 2010
Heterogeneity in resources pervades all modern computing platforms. How do the effects of heterogeneity depend on which resources differ among computers in a platform? Some answers are derived within a formal framework, by comparing heterogeneity in computing power (node-heterogeneity) with heterogeneity in communication speed (link-heterogeneity). The
Beaumont, Olivier, Rosenberg, Arnold
openaire   +3 more sources

Three-dimensional in vitro culture models in oncology research

Cell & Bioscience, 2022
Cancer is a multifactorial disease that is responsible for 10 million deaths per year. The intra- and inter-heterogeneity of malignant tumors make it difficult to develop single targeted approaches.
Camille Jubelin, Javier Muñoz-Garcia, Laurent Griscom, Denis Cochonneau, Emilie Ollivier, Marie-Françoise Heymann, François M. Vallette, Lisa Oliver, Dominique Heymann   +8 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Heterogeneous Development Graphs and Heterogeneous Borrowing [PDF]

, 2002
Development graphs are a tool for dealing with structured specifications in a formal program development in order to ease the management of change and reusing proofs. Often, different aspects of a software system have to be specified in different logics, since the construction of a huge logic covering all needed features would be too complex to be ...
openaire   +2 more sources

Heterogeneous Coded Computation across Heterogeneous Workers [PDF]

2019 IEEE Global Communications Conference (GLOBECOM), 2019
Coded distributed computing framework enables large-scale machine learning (ML) models to be trained efficiently in a distributed manner, while mitigating the straggler effect. In this work, we consider a multi-task assignment problem in a coded distributed computing system, where multiple masters, each with a different matrix multiplication task ...
Yuxuan Sun 0001, Junlin Zhao, Sheng Zhou 0001, Deniz Gündüz   +3 more
openaire   +2 more sources

A coregulatory influence map of glioblastoma heterogeneity and plasticity

npj Precision Oncology
We present GBM-cRegMap, an online resource providing a comprehensive coregulatory influence network perspective on glioblastoma (GBM) heterogeneity and plasticity.
Chloé Bernhard, Konstantinos Geles, Geoffrey Pawlak, Wajdi Dhifli, Aurélien Dispot, Jules Dusol, Maria Kondratova, Sophie Martin, Mélissa Messé, Damien Reita, David Tulasne, Isabelle Van Seuningen, Natacha Entz-Werle, Silvia Anna Ciafrè, Monique Dontenwill, Mohamed Elati   +15 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source