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TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
Membranes, 2023 Breast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly ...
Mayar Soussi +2 more
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Heterogeneity of link weight and the evolution of cooperation [PDF]
, 2015 In this paper, we investigate the effect of "heterogeneity of link weight", heterogeneity of the frequency or amount of interactions among individuals, on the evolution of cooperation. Based on an analysis of the evolutionary prisoner's dilemma game on a
Akiyama Eizo +2 more
core +3 more sources
Dynamic heterogeneity in amorphous materials [PDF]
, 2010 Amorphous solids are mechanically rigid while possessing a disordered structure similar to that of dense liquids. Recent research indicates that dynamical heterogeneity, spatio-temporal fluctuations in local dynamical behavior, might help understanding ...
L. Berthier, Ludovic Berthier, W. Götze
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Chemotherapy Associated Ovarian Failure
Frontiers in Endocrinology, 2020 As the incidence of malignancies in young adults is increasing, fertility preservation in cancer survivors arises as a major concern. Especially among female cancer patients, pregnancy rates are estimated to be 40% lower compared to women of the same age.
Davide Mauri +10 more
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Initiation and dynamics of a spiral wave around an ionic heterogeneity in a model for human cardiac tissue [PDF]
, 2013 In relation to cardiac arrhythmias, heterogeneity of cardiac tissue is one of the most important factors underlying the onset of spiral waves and determining their type.
Dawyndt, Peter +2 more
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Heterogeneity in tuberculosis [PDF]
Nature Reviews Immunology, 2017 Infection with Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), results in a range of clinical presentations in humans. Most infections manifest as a clinically asymptomatic, contained state that is termed latent TB infection (LTBI); a smaller subset of infected individuals present with symptomatic, active TB.
Anthony M, Cadena +2 more
openaire +2 more sources
Extranodal diffuse large B-cell lymphomas: A retrospective case series and review of the literature
Hematology Reports, 2018 Non-Hodgkin lymphomas commonly show extranodal involvement (25-30%) but primary diffuse large B-cell lymphomas(DLBCL) with extranodal localization represent clinically and molecularly distinct entities.
Stergios Boussios +8 more
doaj +1 more source
Measurement of Protein-Protein Interactions through Microscale Thermophoresis (MST)
Bio-Protocol, 2020 The binding interactions of PD-1 and PD-L1 have been studied by surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) over the past few years, but these investigations resulted in controversy regarding the values of the dissociation ...
Magnez Romain +4 more
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Prominent effect of soil network heterogeneity on microbial invasion [PDF]
, 2012 Using a network representation for real soil samples and mathematical models for microbial spread, we show that the structural heterogeneity of the soil habitat may have a very significant influence on the size of microbial invasions of the soil pore ...
Costa, Luciano da F. +5 more
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Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2019 Introduction Symptomatic anti‐Alzheimer's disease (AD) drugs have been commonly used for the treatment of AD. Knowing the natural courses of patients with AD on placebo is highly relevant for clinicians to understand their efficacy and for investigators ...
Mitsunori Watanabe +15 more
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