Results 141 to 150 of about 9,440 (222)

HnRNPC triggers the degradation of MITA to suppress the interferon-mediated antiviral response

open access: yesVeterinary Research
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a group of 34–120 kDa nuclear proteins that have recently been reported to participate in virus replication.
Yanwei Zhang   +8 more
doaj   +1 more source

Review of roles of RNA-binding proteins on NAFLD and the related pharmaceutical measures

open access: yesBiomolecules & Biomedicine
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide and poses a serious threat to public health. NAFLD is considered a risk factor for metabolic syndrome (MS) and is closely associated with type 2 diabetes ...
Changjin Li   +3 more
doaj   +1 more source

Nuclear organization of splicing small nuclear ribonucleoproteins in adenovirus-infected cells [PDF]

open access: yes, 1993
We have studied the effect of adenovirus infection on the nuclear organization of splicing small nuclear ribonucleoproteins (snRNPs) in HeLa cells. In uninfected HeLa cells, snRNPs are widespread throughout the nucleoplasm but also are concentrated in ...
Lamond, A.; id_orcid   +3 more
core  

Regulation of endocrine cell alternative splicing revealed by single-cell RNA sequencing in type 2 diabetes pathogenesis

open access: yesCommunications Biology
The prevalent RNA alternative splicing (AS) contributes to molecular diversity, which has been demonstrated in cellular function regulation and disease pathogenesis. However, the contribution of AS in pancreatic islets during diabetes progression remains
Jin Wang   +8 more
doaj   +1 more source

The up-regulation of SYNCRIP promotes the proliferation and tumorigenesis via DNMT3A/p16 in colorectal cancer

open access: yesScientific Reports
Heterogeneous nuclear ribonucleoproteins (hnRNPs), a group of proteins that control gene expression, have been implicated in many post-transcriptional processes.
Chenglong Li   +4 more
doaj   +1 more source

Model investigations on the structure of heterogeneous nuclear ribonucleoproteins.

open access: yesActa biochimica Polonica, 1984
Protein HD40 , an RNA-helix destabilizing protein (Mr 40 000) is the major component of 30S heterogeneous nuclear ribonucleoprotein particles (hnRNP) from Artemia salina. The physical properties and the amino acid composition of HD40 are analogous to those of a group of well conserved core hnRNP proteins of higher eukaryotes. HD40 binds to and disrupts
S K, Głowacka   +3 more
openaire   +1 more source

PTBP1 Regulates DNMT3B Alternative Splicing by Interacting With RALY to Enhance the Radioresistance of Prostate Cancer

open access: yesAdvanced Science
Radiotherapy is a curative arsenal for prostate cancer (PCa), but radioresistance seriously compromises its effectiveness. Dysregulated RNA splicing factors are extensively involved in tumor progression.
Haixia He   +18 more
doaj   +1 more source

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