Results 191 to 200 of about 9,440 (222)

Independent deposition of heterogeneous nuclear ribonucleoproteins and small nuclear ribonucleoprotein particles at sites of transcription. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1992
The major nuclear ribonucleoproteins (RNPs) involved in pre-mRNA processing are classified in broad terms either as small nuclear RNPs (snRNPs), which are major participants in the splicing reaction, or heterogeneous nuclear RNPs (hnRNPs), which ...
G Raychaudhuri, Walther J van Venrooij, W J Habets   +2 more
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Heterogeneous nuclear ribonucleoprotein complexes

Molecular Biology Reports, 1990
Heterogeneous nuclear r ibonuc leopro te ins (hnRNPs) associate with RNA polymerase II transcripts immediately following the initiation of transcription to form hnRNP complexes. These structures are the functional assemblies within which hnRNAs and pre-mRNAs exist in the nucleus.
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Heterogeneous Nuclear Ribonucleoproteins: Role in RNA Splicing

Science, 1986
Splicing in vitro of a messenger RNA (mRNA) precursor (pre-mRNA) is inhibited by a monoclonal antibody to the C proteins (anti-C) of the heterogeneous nuclear RNA (hnRNA)-ribonucleoprotein (hnRNP) particles. This antibody, 4F4, inhibits an early step of the reaction: cleavage at the 3′ end of the upstream exon and the formation of the ...
Y D, Choi, P J, Grabowski, P A, Sharp, G, Dreyfuss   +3 more
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Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

Trends in Biochemical Sciences, 1988
Abstract Heterogeneous nuclear ribonucleoprotein (hnRNP) particles, the structures that package hnRNA, are one of the major constituents of the nucleus. Recent work has led to the immunopurification of hnRNP particles and the identification of their proteins, and demonstrated a role for hnRNP proteins in mRNA splicing.
G, Dreyfuss, M S, Swanson, S, Piñol-Roma   +2 more
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Role of heterogeneous nuclear ribonucleoprotein K in tumor development

Journal of Cellular Biochemistry, 2019
AbstractHeterogeneous nuclear ribonucleoprotein K (hnRNP K) is an RNA/DNA special binding protein that participates in regulating the expression of related genes, transcription, RNA alternative splicing, translation, posttranslational modification, cell signal transduction, cell movement, interacts with ncRNAs, and induces angiogenesis.
Yuting Chen, Ying Zeng, Zheng Xiao, Shi Chen, Yukun Li, Juan Zou, Xi Zeng   +6 more
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The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism

BioEssays, 1996
AbstractIn eukaryotic cells, messenger RNAs are formed by extensive posttranscriptional processing of primary transcripts, assembled with a large number of proteins and processing factors in ribonucleoprotein complexes. The protein moiety of these complexes mainly constitutes a class of about 20 major polypeptides called heterogeneous nuclear ...
F, Weighardt, G, Biamonti, S, Riva
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A chicken mRNA similar to heterogeneous nuclear ribonucleoprotein H1

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2004
Heterogeneous nuclear ribonucleoproteins are predominantly nuclear RNA-binding proteins that function in a variety of cellular activities. The objective of these experiments was to clone a cDNA for a chicken protein similar to other previously reported heterogeneous ribonucleoproteins for other species.
Paul E, Mozdziak, Carol, Giamario, Julia J, Dibner, Darell W, McCoy   +3 more
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Limited nuclease digestion of heterogeneous nuclear ribonucleoprotein in nuclei

Biochemical and Biophysical Research Communications, 1979
Abstract We have used limited nuclease digestion of nuclei to probe the structure of nuclear ribonucleoprotein (nRNP). Analysis of [ 3 H]uridine-labeled heterogeneous nuclear RNA isolated from nuclease digested nuclei revealed preferential generation of discrete bands of RNA ranging in size from 1.5 × 10 5 to 6 × 10 5 daltons.
M Z, Wahrman, L H, Augenlicht
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Origins of Binding Specificity of the A1 Heterogeneous Nuclear Ribonucleoprotein

Biochemistry, 1996
The A1 heterogeneous nuclear ribonucleoprotein (hnRNP) is the best studied of the "core" hnRNP proteins that are tightly associated with heterogeneous nuclear RNA (hnRNA) within eukaryotic nuclei. Previous studies suggested that hnRNP A1 preferentially binds (under nonequilibrium conditions) to the pyrimidine-rich span of sequence at the 3'splice site ...
N, Abdul-Manan, S M, O'Malley, K R, Williams   +2 more
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Heterogeneous Nuclear Ribonucleoproteins Participate in Hepatitis E Virus Replication

Journal of Molecular Biology, 2020
Coordinated assembly of viral and host factors is essential for the successful propagation of viruses as well as the generation of host antiviral response. Previous studies from our group, as well as from other groups, have identified host proteins interacting with various components of the hepatitis E virus (HEV).
Kunal D. Pingale, Gayatri D. Kanade, Yogesh A. Karpe   +2 more
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