Results 161 to 170 of about 84,743 (283)

Respiratory virus-induced heterologous immunity: Part of the problem or part of the solution? [PDF]

Allergo J Int, 2018
Pusch E, Renz H, Skevaki C.
europepmc   +2 more sources

MORITS: An improved method to predict peptides from heterologous proteins that are recognized by the same T-cell receptor

Scientific Reports
Antigen-specific priming of T cells results in the activation of T cells that exert effector functions by interaction of their T-cell receptor (TCR) with the corresponding self-MHC molecule presenting a peptide on the surface of a target cell.
Matthias Bruhn, Moritz Spatz, Ulrich Kalinke   +2 more
doaj   +1 more source

Navigating Oral Food Challenges in Clinical Trials to Keep the Science Moving Forward

Allergy, EarlyView.
ABSTRACT The oral food challenge (OFC) has long been the reference standard for food allergy diagnosis, as well as to confirm natural development of oral tolerance. The utilization of OFCs has significantly broadened from its role in defining disease to defining participant eligibility, individual allergen reactivity thresholds and treatment outcomes ...
Edwin H. Kim, J. Andrew Bird, Helen A. Brough, David M. Fleischer, Stacie M. Jones, Ildiko Kun, Wayne Shreffler, Claire Van Eenwyk, Brian P. Vickery, Julie Wang, Alexandra F. Santos   +10 more
wiley   +1 more source

A multi-component prime-boost vaccination regimen with a consensus MOMP antigen enhances Chlamydia trachomatis clearance [PDF]

, 2016
Badamchi-Zadeh, A, Barinaga, G, Follman, F, Gomes, JP, Korber, BT, McKay, PF, Nunes, A, Shattock, RJ, Tregoning, JS, Walters, AA   +9 more
core   +1 more source

IgE Antibody Function and Mast Cell Activation to Egg in Children Undergoing Baked and Loosely Cooked Egg Challenges

Allergy, EarlyView.
MAT is dependent on the presence of allergen‐specific IgE and can provide false‐negative results in allergic patients with low allergen‐specific IgE levels. MAT and BAT are moderately correlated. MAT can be used as a surrogate of BAT, when fresh blood is not available or in the case of patients with non‐releaser basophils.
Vikki Houghton, Vasco Claro, Nur Romli, Zainab Jama, Grammatiki Antoneria, Matthew Kwok, Alexandra F. Santos   +6 more
wiley   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Comparing the protection of heterologous booster of inhaled Ad5-nCoV vaccine and hybrid immunity against Omicron BA.5 infection: a cohort study of hospital staff in China

BMC Infectious Diseases
Background After the exit “zero-COVID” strategy in mainland China by the end of 2022, a large-scale COVID-19 outbreak seeded by Omicron variants occurred.
Kai Wang, Ting Zeng, Zihao Guo, Jing Liang, Shengzhi Sun, Yongkang Ni, Chunyan Yan, Liang Yin, Lan Wang, Hui Li, Kailu Wang, Marc K.C. Chong, Naijun Tang, Jianghong Dai, Zhaohui Luo, Shi Zhao   +15 more
doaj   +1 more source

A vaccination programme combining a live attenuated Salmonella Typhimurium and an autogenous inactivated Salmonella Enteritidis vaccine confers protection and reduces ovarian colonisation with the Salmonella Enteritidis isolate 7A, PT12

Australian Veterinary Journal, EarlyView.
Salmonella enterica serovar Enteritidis (SE) can colonise chicken ovaries and contaminate eggs, posing a global risk of human gastroenteritis, often linked to raw or undercooked eggs. Control options for SE outbreaks in Australia are limited; autogenous SE vaccines are commonly used, while live attenuated Salmonella Typhimurium (ST) vaccines are ...
JA Quinteros, TB Wilson, A Anwar, T Scott, P Shil, AH Noormohammadi, G Underwood, PC Scott   +7 more
wiley   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini, Riccardo Camilotto, Michele Maritan, Erika Morrone, Stephen Afriyie Boateng, Anna Vacilotto, Salvatore Pacifico, Remo Guerrini, Nurulain T. Zaveri, Girolamo Calo'   +9 more
wiley   +1 more source