Results 191 to 200 of about 48,636 (248)

Entering the Age of Specificity in T Cell Immunity

open access: yesImmunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT The discovery of MHC restriction, the resolution of peptide–MHC structure, and the identification of the T cell receptor gene quickly centered epitope‐level specificity as a core concern of T cell biology. Epitope mapping culminated in functional peptide‐based stimulation assays and tetramer staining, which together provide exquisite ...
Paul G. Thomas
wiley   +1 more source

Efficacy Assessment of Montanide GEL 02 PR and Liposome‐Based Encapsulation as Adjuvants for an FrpA Subunit Vaccine Against Photobacteriosis in Solea senegalensis

open access: yesJournal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT Photobacteriosis is a major threat to marine aquaculture, and the siderophore transporter FrpA represents a promising target for effective subunit vaccine development. In this study, we evaluated Montanide GEL 02 PR and phosphatidylcholine‐based liposomes as aqueous and safer alternatives to Freund's adjuvant for an FrpA‐based subunit vaccine ...
Marta A. Lages   +7 more
wiley   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

open access: yesJournal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun   +10 more
wiley   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 10, Page 3569-3592, October 2026.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia   +12 more
wiley   +1 more source

A Csi‐miR3954b‐CsCE70/CsPLA1 Regulatory Module Enhances Citrus Fruit Resistance to Penicillium digitatum by Promoting Phenolic Acid and Flavonoid Biosynthesis

open access: yesMolecular Plant Pathology, Volume 27, Issue 10, October 2026.
Csi‐miR3954b targets CsCE70 and CsPLA1, promoting the synthesis of phenolic acids and flavonoids, thereby enhancing citrus resistance to postharvest green mould. ABSTRACT Green mould is one of the major postharvest diseases affecting citrus. Although evidence indicates that microRNAs (miRNAs) participate in plant defence responses, their roles and ...
Jixin Tian   +7 more
wiley   +1 more source

Dodder seedlings benefit from apoplastic nutrition by inducing SWEET15‐mediated unloading of sucrose from the host's phloem

open access: yesNew Phytologist, Volume 252, Issue 2, Page 829-842, October 2026.
Cuscuta reflexa infection sites. Summary Cuscuta species are holoparasitic plants that penetrate host stems with haustoria, connect to the vasculature and exhaust water, nutrients and carbohydrates. Parasite seedlings possess only limited maternal reserves and the development of a vascular connection takes several days.
Maleen Hartenstein   +10 more
wiley   +1 more source

Dual-antigen AdV5 vaccines against Crimean-Congo hemorrhagic fever virus induce superior humoral and Th1-biased cellular immunity. [PDF]

open access: yesSci Rep
Hanifehnezhad A   +12 more
europepmc   +1 more source

Turnip mosaic virus utilizes the lipid droplet biogenesis machinery to facilitate its propagation in plants

open access: yesNew Phytologist, Volume 252, Issue 2, Page 797-816, October 2026.
Potyvirus turnip mosaic virus induces neutral lipid accumulation and lipid droplet biogenesis in infected leaves for its own benefit. See also the Commentary on this article by May & Nagy, 252: 525–527. Summary Lipid droplets (LDs), which are dedicated to storing neutral lipids (NLs), are dynamic organelles involved in numerous other functions ...
Léna Jambou   +16 more
wiley   +1 more source

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