Structural and Functional Siderophore Remodeling by Enzymatic Delipidation
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog +5 more
wiley +2 more sources
A Fungal Glycoside Hydrolase From Colletotrichum asianum Mini-Chromosomes Targets Host Chitinase to Suppress Plant Immunity. [PDF]
Wang R +9 more
europepmc +1 more source
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang +6 more
wiley +1 more source
Significance Statement While the biosynthetic pathway of tea catechins is well established, how post‐translational modifications govern this process has remained elusive. This study uncovers a regulatory module in which the E3 ubiquitin ligase CsRNF targets the transcription factor CsHSF24 for degradation, thereby controlling expression of the key ...
Xinzhuan Yao +9 more
wiley +1 more source
Editorial: Immune-related mechanisms in apicomplexan and trypanosomatid parasites. [PDF]
Arranz-Solís D, Mukhopadhyay D.
europepmc +1 more source
Heat-killed <i>Mycobacterium tuberculosis</i>-induced trained immunity elicits antitumor activity in PBMCs from colon cancer patients with unresponsiveness to anti-PD-1 <i>in vitro</i>. [PDF]
Bıçakcıoğlu G +12 more
europepmc +1 more source
From injection to inhalation: A STING-activating mucosal adjuvant reprograms vaccination. [PDF]
Wang W, Wang M, Lu L, Jiang S, Liu Z.
europepmc +1 more source
The M91 metallopeptidase domain of the T6SS effector protein SED_RS06335 encoded in Salmonella Dublin SPI-19 exhibits antibacterial activity. [PDF]
Vargas-Del Río C +9 more
europepmc +1 more source
Comprehensive evaluation of an emergency monovalent SAT1 foot-and-mouth-disease vaccine: Antigen quality, product consistency, and protective efficacy. [PDF]
Abousenna MS +8 more
europepmc +1 more source

