Results 221 to 230 of about 84,743 (283)

Protein Priming Followed by a Replication-Competent VSV-GP Vector Boost Induces Sustained Immune Control in Therapeutic Hepatitis B Vaccination. [PDF]

Vaccines (Basel)
Su J, Kosinska AD, Miko S, Ates Öz E, Laer DV, Kimpel J, Protzer U.   +6 more
europepmc   +1 more source

SARS‐CoV‐2 Variants and Immune Evasion: Mapping the Future of Vaccine Design

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT The evolutionary trajectory of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) has progressed through several distinct phases since its zoonotic emergence, transitioning from initial human adaptation to an era of rapid antigenic drift and complex immune evasion. As of early 2026, the global landscape is dominated by highly evolved
Fatih Uzer, Fulya Erendor, Salih Sanlioglu   +2 more
wiley   +1 more source

Comparative Humoral Immune Responses Induced by Live-Attenuated and Inactivated Porcine Epidemic Diarrhea Vaccines in Replacement Gilts. [PDF]

Vaccines (Basel)
Boonsoongnern P, Boodde O, Chumsing W, Jirawattanapong P, Sukmak M, Woonwong Y, Thanantong N, Wajjwalku W, Boonsoongnern A.   +8 more
europepmc   +1 more source

A Systematic Review of Graft‐Related Complications and Recurrence Following Minimally Invasive Sacrocolpopexy With Xenografts and Allografts

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 6, Page 1157-1165, May 2026.
ABSTRACT Background Biological grafts are proposed as an alternative to synthetic grafts in sacrocolpopexy (SC) to reduce complications such as graft exposure and immunologic reactions. However, concerns remain long‐term durability. This systematic review and meta‐analysis assess recurrence rates and graft‐related complications (GRC) in minimally ...
Marije A. Boom, Margot van Genderen, Paul M. Verheijen, Esther C. J. Consten, Henk W. R. Schreuder, Steven E. Schraffordt Koops   +5 more
wiley   +1 more source

A single-dose mRNA vaccine induces potent and long-lasting humoral and cellular immunity against the varicella-zoster virus in a murine model. [PDF]

Front Immunol
Cheng W, Ren N, Xie L, Zhou W, Quan R, Wei H.   +5 more
europepmc   +1 more source

Transition From Land to Sea: Comparative Genomics Illuminates the Adaptive Evolution of the Intertidal Spider

Molecular Ecology Resources, Volume 26, Issue 4, May 2026.
ABSTRACT Spiders are renowned for their ecological versatility and silk‐based innovations in materials science, yet marine environments remain virtually uncolonized by this predominantly terrestrial lineage. A striking exception is the obligate intertidal spider genus Desis, whose members have evolved extraordinary physiological and behavioural ...
Fan Li, Yunyun Lv, Chao Bian, Quentin Moana Perrin, Yubo Zhang, Yixiao Wang, Lei Cao, Long Yu, Shengtao Guo, Wei Zhang, Qiong Shi, Daiqin Li   +11 more
wiley   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

Brain Pathology, Volume 36, Issue 3, May 2026.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown, Jeanne K. Brooks, Louise Kelly, Madeline M. Vroom, Matthew Longo, Jean‐Cosme Dodart, Roxana Carare, Justin D. Boyd   +7 more
wiley   +1 more source

Identification and Functional Characterization of Novel and Recurrent NTRK1 Variants in Chinese Families With Congenital Insensitivity to Pain With Anhidrosis: A Combined Clinical, Genetic, and Functional Study

European Journal of Neurology, Volume 33, Issue 5, May 2026.
This study investigates four Chinese families with congenital insensitivity to pain with anhidrosis (CIPA). Through next‐generation sequencing, we identified seven NTRK1 variants, including two novel mutations. Functional characterization of five identified missense and indel variants revealed distinct disruptions in the NGF‐TrkA pathway, ranging from ...
Yaqiong Ren, Yue Cao, Fangfang Cheng, Jin Dai, Yuan Zhang, Xinxin Wang, Jiali Chen, Lijun Zhou, Xiaoxiang Song, Hongying Wang   +9 more
wiley   +1 more source

Type I interferon signaling is required for resistance to primary influenza virus infection and vaccine-induced long-term immunity. [PDF]

J Virol
Kim K-H, Hwang HS, Pal SS, Tien Le CT, Grovenstein P, Yeasmin M, Song JM, Kwon Y-M, Wang B, Kang S-M.   +9 more
europepmc   +1 more source

Ustilago maydis Phosphatidic Acid and Phosphatidylserine‐Targeting Secreted Lipase Lip3 Is Involved in Pathogenesis

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
Ustilago maydis secreted lipase, Lip3 targets PA and PS and alkalinises the host apoplast, thus promoting virulence. Loss of Lip3 results in reduced apoplastic pH and decreased pathogenicity. ABSTRACT Lipases constitute important virulence factors. By targeting specific lipids involved in various cellular processes, lipases regulate growth, development,
Anisha Roy, Rituparna Mondal, Anupama Ghosh   +2 more
wiley   +1 more source