Results 41 to 50 of about 84,743 (283)

Heterologous prime-boost vaccination with H3N2 influenza viruses of swine favors cross-clade antibody responses and protection [PDF]

, 2017
The emergence of multiple novel lineages of H1 and H3 influenza A viruses in swine has confounded control by inactivated vaccines. Because of substantial genetic and geographic heterogeneity among circulating swine influenza viruses, one vaccine strain ...
Claes, Gerwin, Cox, Eric, Krammer, Florian, Mancera Gracia, José Carlos, Qiu, Yu, Sys, Lieve, Trus, Ivan, Van Reeth, Kristien, Versnaeyen, Han   +8 more
core   +2 more sources

Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity

Virology Journal, 2023
Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral ...
Saina Beitari, Diana Duque, Jegarubee Bavananthasivam, Melissa Hewitt, Jagdeep K. Sandhu, Ita Hadžisejdić, Anh Tran   +6 more
doaj   +1 more source

Protection of hybrid immunity against SARS-CoV-2 reinfection and severe COVID-19 during periods of Omicron variant predominance in Mexico

Frontiers in Public Health, 2023
BackgroundWith the widespread transmission of the Omicron SARS-CoV-2 variant, reinfections have become increasingly common. Here, we explored the role of immunity, primary infection severity, and variant predominance in the risk of reinfection and severe
José Antonio Montes-González, Christian Arturo Zaragoza-Jiménez, Neftali Eduardo Antonio-Villa, Carlos A. Fermín-Martínez, Carlos A. Fermín-Martínez, Daniel Ramírez-García, Arsenio Vargas-Vázquez, Rosaura Idania Gutiérrez-Vargas, Gabriel García-Rodríguez, Hugo López-Gatell, Sergio Iván Valdés-Ferrer, Omar Yaxmehen Bello-Chavolla   +11 more
doaj   +1 more source

Immune complex glomerulonephritis is induced in rats immunized with heterologous myeloperoxidase [PDF]

Clinical and Experimental Immunology, 1994
SUMMARY Anti-neutrophil cytoplasmic antibodies (ANCA), including anti-myeloperoxidase (MPO) antibodies, are associated with pauci-immune necrotizing small vessel vasculitis or glomerulonephritis, 1n order to substantiate a pathogenic role for ANCA, an animal model of pauci-immune ANCA-induced glomerulonephritis or vasculitis is required.
J J, Yang, J C, Jennette, R J, Falk
openaire   +2 more sources

Recombinant monovalent llama-derived antibody fragments (VHH) to rotavirus VP6 protect neonatal gnotobiotic piglets against human rotavirus-induced diarrhea [PDF]

, 2013
Group A Rotavirus (RVA) is the leading cause of severe diarrhea in children. The aims of the present study were to determine the neutralizing activity of VP6-specific llama-derived single domain nanoantibodies (VHH nanoAbs) against different RVA strains ...
Alvarado, Carmen, Bok, Karin, Bok, Marina, Chattha, Kuldeep S., Escribano, José M., Fernández, Fernando, Garaicoechea, Lorena Laura, Gómez Sebastián, Silvia, Lasa, Rodrigo, Nuñez, Carmen, Parreño, Gladys Viviana, Saif, Linda J., Vega, Celina Guadalupe, Vlasova, Anastasia N., Wigdorovitz, Andrés   +14 more
core   +3 more sources

Primary ChAdOx1 vaccination does not reactivate pre-existing, cross-reactive immunity

Frontiers in Immunology, 2023
Currently available COVID-19 vaccines include inactivated virus, live attenuated virus, mRNA-based, viral vectored and adjuvanted protein-subunit-based vaccines.
Larissa Henze, Larissa Henze, Julian Braun, Julian Braun, Lil Meyer-Arndt, Lil Meyer-Arndt, Lil Meyer-Arndt, Lil Meyer-Arndt, Karsten Jürchott, Karsten Jürchott, Maike Schlotz, Janine Michel, Marica Grossegesse, Maike Mangold, Maike Mangold, Manuela Dingeldey, Manuela Dingeldey, Beate Kruse, Beate Kruse, Pavlo Holenya, Norbert Mages, Norbert Mages, Norbert Mages, Ulf Reimer, Maren Eckey, Karsten Schnatbaum, Holger Wenschuh, Bernd Timmermann, Florian Klein, Florian Klein, Florian Klein, Andreas Nitsche, Claudia Giesecke-Thiel, Lucie Loyal, Lucie Loyal, Andreas Thiel, Andreas Thiel   +36 more
doaj   +1 more source

Heterologous immunity revisited

Parasitology, 2001
Heterologous immunity, or protection by one invading organism against another across phylogenetic divides, has been recognised for decades. It was initially thought to operate largely through enhancement of phagocytosis, but this explanation became untenable when it was realised it worked extremely well against intraerythrocytic protozoa and killed ...
openaire   +2 more sources

Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges [PDF]

, 2014
Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal health, yet effective control measures have proven difficult to implement, and novel means of controlling their replication in arthropod vectors, such as mosquitoes, are
Dietrich, Isabelle, Kohl, Alain, Rainey, Stephanie M., Shah, Pranav   +3 more
core   +1 more source

The impact of vaccines on heterologous adaptive immunity [PDF]

Clinical Microbiology and Infection, 2019
Vaccines induce antigen-specific memory in adaptive immune cells that enables long-lived protection against the target pathogen. In addition to this, several vaccines have beneficial effects greater than protection against their target pathogen. These non-specific effects are proposed to be the result of vaccine-induced immunomodulation. In the case of
N L, Messina, P, Zimmermann, N, Curtis
openaire   +2 more sources

Past Life and Future Effects—How Heterologous Infections Alter Immunity to Influenza Viruses

Frontiers in Immunology, 2018
Influenza virus frequently mutates due to its error-prone polymerase. This feature contributes to influenza virus’s ability to evade pre-existing immunity, leading to annual epidemics and periodic pandemics.
Aisha Souquette, Paul G. Thomas
doaj   +1 more source