Results 21 to 30 of about 48,636 (248)

MHC basis of T cell-dependent heterologous immunity to arenaviruses [PDF]

open access: yesVirology, 2014
Michael A Brehm   +2 more
exaly   +2 more sources

Subcutaneous BCG vaccination protects against streptococcal pneumonia via regulating innate immune responses in the lung

open access: yesEMBO Molecular Medicine, 2023
Bacillus Calmette‐Guérin (BCG) still remains the only licensed vaccine for TB and has been shown to provide nonspecific protection against unrelated pathogens.
Alisha Kang   +10 more
doaj   +1 more source

Heterologous effects of vaccination and trained immunity [PDF]

open access: yesClinical Microbiology and Infection, 2019
Vaccines are applied to large populations, but only recently has research into immunologic responses and mechanisms started to increase exponentially. Some live vaccines, such as the tuberculosis vaccine bacillus Calmette-Guérin, protect against other infections nonspecifically by eliciting complex immune responses which are not specific antibody ...
Gyssens, I.C.J.   +2 more
openaire   +3 more sources

Immunization with an autotransporter protein of Orientia tsutsugamushi provides protective immunity against scrub typhus. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
BACKGROUND:Scrub typhus is an acute febrile disease caused by Orientia tsutsugamushi infection. Recently, the rapid increase of scrub typhus incidence in several countries within the endemic region has become a serious public health issue.
Na-Young Ha   +7 more
doaj   +1 more source

Trained-immunity and cross-reactivity for protection: insights from the coronavirus disease 2019 and monkeypox emergencies for vaccine development

open access: yesExploration of Immunology, 2023
The emergence and re-emergence of pathogens is a public-health concern, which has become more evident after the coronavirus disease 2019 (COVID-19) pandemic and the monkeypox outbreaks in early 2022.
Amanda Izeli Portilho   +1 more
doaj   +1 more source

SPECIFIC HETEROLOGOUS ENHANCEMENT OF IMMUNE RESPONSES [PDF]

open access: yesThe Journal of Experimental Medicine, 1973
The mixing of two histoincompatible human lymphocyte cell lines generated the release of a soluble factor which was capable of nonspecifically enhancing the in vitro immune response of normal mouse spleen cells against sheep erythrocytes. When active supernates were subjected to exclusion chromatography on Sephadex G-150 and BioGel P-150, the active ...
A S, Rubin, A B, MacDonald, A H, Coons
openaire   +2 more sources

In-depth analysis of T cell immunity and antibody responses in heterologous prime-boost-boost vaccine regimens against SARS-CoV-2 and Omicron variant

open access: yesFrontiers in Immunology, 2022
With the emergence of novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Variants of Concern (VOCs), vaccination studies that elucidate the efficiency and effectiveness of a vaccination campaign are critical to assess the durability and ...
Natalie Heinen   +30 more
doaj   +1 more source

Immune complex glomerulonephritis is induced in rats immunized with heterologous myeloperoxidase [PDF]

open access: yesClinical and Experimental Immunology, 1994
SUMMARY Anti-neutrophil cytoplasmic antibodies (ANCA), including anti-myeloperoxidase (MPO) antibodies, are associated with pauci-immune necrotizing small vessel vasculitis or glomerulonephritis, 1n order to substantiate a pathogenic role for ANCA, an animal model of pauci-immune ANCA-induced glomerulonephritis or vasculitis is required.
J J, Yang, J C, Jennette, R J, Falk
openaire   +2 more sources

Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity

open access: yesVirology Journal, 2023
Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral ...
Saina Beitari   +6 more
doaj   +1 more source

Protection of hybrid immunity against SARS-CoV-2 reinfection and severe COVID-19 during periods of Omicron variant predominance in Mexico

open access: yesFrontiers in Public Health, 2023
BackgroundWith the widespread transmission of the Omicron SARS-CoV-2 variant, reinfections have become increasingly common. Here, we explored the role of immunity, primary infection severity, and variant predominance in the risk of reinfection and severe
José Antonio Montes-González   +11 more
doaj   +1 more source

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