Results 21 to 30 of about 48,636 (248)
MHC basis of T cell-dependent heterologous immunity to arenaviruses [PDF]
Michael A Brehm +2 more
exaly +2 more sources
Bacillus Calmette‐Guérin (BCG) still remains the only licensed vaccine for TB and has been shown to provide nonspecific protection against unrelated pathogens.
Alisha Kang +10 more
doaj +1 more source
Heterologous effects of vaccination and trained immunity [PDF]
Vaccines are applied to large populations, but only recently has research into immunologic responses and mechanisms started to increase exponentially. Some live vaccines, such as the tuberculosis vaccine bacillus Calmette-Guérin, protect against other infections nonspecifically by eliciting complex immune responses which are not specific antibody ...
Gyssens, I.C.J. +2 more
openaire +3 more sources
Immunization with an autotransporter protein of Orientia tsutsugamushi provides protective immunity against scrub typhus. [PDF]
BACKGROUND:Scrub typhus is an acute febrile disease caused by Orientia tsutsugamushi infection. Recently, the rapid increase of scrub typhus incidence in several countries within the endemic region has become a serious public health issue.
Na-Young Ha +7 more
doaj +1 more source
The emergence and re-emergence of pathogens is a public-health concern, which has become more evident after the coronavirus disease 2019 (COVID-19) pandemic and the monkeypox outbreaks in early 2022.
Amanda Izeli Portilho +1 more
doaj +1 more source
SPECIFIC HETEROLOGOUS ENHANCEMENT OF IMMUNE RESPONSES [PDF]
The mixing of two histoincompatible human lymphocyte cell lines generated the release of a soluble factor which was capable of nonspecifically enhancing the in vitro immune response of normal mouse spleen cells against sheep erythrocytes. When active supernates were subjected to exclusion chromatography on Sephadex G-150 and BioGel P-150, the active ...
A S, Rubin, A B, MacDonald, A H, Coons
openaire +2 more sources
With the emergence of novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Variants of Concern (VOCs), vaccination studies that elucidate the efficiency and effectiveness of a vaccination campaign are critical to assess the durability and ...
Natalie Heinen +30 more
doaj +1 more source
Immune complex glomerulonephritis is induced in rats immunized with heterologous myeloperoxidase [PDF]
SUMMARY Anti-neutrophil cytoplasmic antibodies (ANCA), including anti-myeloperoxidase (MPO) antibodies, are associated with pauci-immune necrotizing small vessel vasculitis or glomerulonephritis, 1n order to substantiate a pathogenic role for ANCA, an animal model of pauci-immune ANCA-induced glomerulonephritis or vasculitis is required.
J J, Yang, J C, Jennette, R J, Falk
openaire +2 more sources
Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunity
Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral ...
Saina Beitari +6 more
doaj +1 more source
BackgroundWith the widespread transmission of the Omicron SARS-CoV-2 variant, reinfections have become increasingly common. Here, we explored the role of immunity, primary infection severity, and variant predominance in the risk of reinfection and severe
José Antonio Montes-González +11 more
doaj +1 more source

