Unsolved Puzzles Surrounding HCV Immunity: Heterologous Immunity Adds Another Dimension [PDF]
International Journal of Molecular Sciences, 2017 Chronic infection with hepatitis C virus (HCV) afflicts 3% of the world’s population and can lead to serious and late-stage liver diseases. Developing a vaccine for HCV is challenging because the correlates of protection are uncertain and traditional ...
Babita Agrawal +2 more
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MHC basis of T cell-dependent heterologous immunity to arenaviruses [PDF]
Virology, 2014 Having a history of infection with one pathogen may sometimes provide a level of T cell-dependent protective heterologous immunity to another pathogen.
Keith A Daniels +2 more
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Evaluation of non-reciprocal heterologous immunity between unrelated viruses [PDF]
Virology, 2015 Heterologous immunity refers to the phenomenon whereby a history of an immune response against one pathogen can provide a level of immunity to a second unrelated pathogen.
Liisa K Selin, Raymond M Welsh
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HETEROLOGOUS IMMUNITY STUDIES IN CALVES IN IRAN [PDF]
Iranian Journal of Public Health, 1976 In a series of heterologous immunity studies S. haematobium, S. bovis and O. turkestanicum in calves, a large number of S. haematobium cercariae (21,000 cercariae) were used repeatedly as the immunization agent.
J. Massoud
doaj +4 more sources
Heterologous effects of vaccination and trained immunity [PDF]
Clinical Microbiology and Infection, 2019 Vaccines are applied to large populations, but only recently has research into immunologic responses and mechanisms started to increase exponentially. Some live vaccines, such as the tuberculosis vaccine bacillus Calmette-Guérin, protect against other infections nonspecifically by eliciting complex immune responses which are not specific antibody ...
Gyssens, I.C.J. +2 more
openaire +4 more sources
In-depth analysis of T cell immunity and antibody responses in heterologous prime-boost-boost vaccine regimens against SARS-CoV-2 and Omicron variant [PDF]
Frontiers in Immunology, 2022 With the emergence of novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Variants of Concern (VOCs), vaccination studies that elucidate the efficiency and effectiveness of a vaccination campaign are critical to assess the durability and ...
Natalie Heinen +30 more
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The impact of vaccines on heterologous adaptive immunity [PDF]
Clinical Microbiology and Infection, 2019 Vaccines induce antigen-specific memory in adaptive immune cells that enables long-lived protection against the target pathogen. In addition to this, several vaccines have beneficial effects greater than protection against their target pathogen. These non-specific effects are proposed to be the result of vaccine-induced immunomodulation. In the case of
Petra Zimmermann, Nigel Curtis
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Cross-Protection in PRRSV: Mechanisms, Limitations, and Implications for Vaccine Design [PDF]
PathogensPorcine reproductive and respiratory syndrome (PRRS) remains one of the most economically devastating diseases in global swine production. The causative agent, PRRS virus (PRRSV), comprises two genetically distinct species—PRRSV-1 and PRRSV-2—that differ
Sergei A. Raev +5 more
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β-Glucan training induces stimulus-dependent immune and metabolic modulation in head kidney leukocytes that persists for several days in Atlantic salmon (Salmo salar L.) [PDF]
Frontiers in ImmunologyThe innate immune system of fish has conventionally been considered incapable of immunological memory, but is now being recognised as exhibiting memory-like features known as trained immunity.
Thinh Hoang Nhan +4 more
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Cross-protective immunity elicited by heterologous DNA prime/subunit or adenovirus boost regimens against bovine viral diarrhea virus [PDF]
BMC Veterinary ResearchBovine viral diarrhea (BVD) poses a substantial economic threat to the cattle industry, necessitating vaccines with broad cross-protective immunity. Heterologous prime-boost immunization represents a promising strategy to broaden immune protection by ...
Mingguo Xu +13 more
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