Results 1 to 10 of about 49,719 (277)

Heterologous Immunity Between SARS-CoV-2 and Pathogenic Bacteria [PDF]

Frontiers in Immunology, 2022
Heterologous immunity, when the memory T cell response elicited by one pathogen recognizes another pathogen, has been offered as a contributing factor for the high variability in coronavirus disease 2019 (COVID-19) severity outcomes.
Peter J. Eggenhuizen, Boaz H. Ng, Janet Chang, Rachel M.Y. Cheong, Anusha Yellapragada, Wey Y. Wong, Yi Tian Ting, Julie A. Monk, Poh-Yi Gan, Poh-Yi Gan, Stephen R. Holdsworth, Stephen R. Holdsworth, Joshua D. Ooi   +12 more
doaj   +4 more sources

Vaccination and heterologous immunity: educating the immune system. [PDF]

Trans R Soc Trop Med Hyg, 2015
This review discusses three inter-related topics: (1) the immaturity of the neonatal and infant immune response; (2) heterologous immunity, where prior infection history with unrelated pathogens alters disease outcome resulting in either enhanced protective immunity or increased immunopathology to new infections, and (3) epidemiological human vaccine ...
Gil A, Kenney LL, Mishra R, Watkin LB, Aslan N, Selin LK.   +5 more
europepmc   +6 more sources

Heterologous Immunity: Role in Natural and Vaccine-Induced Resistance to Infections [PDF]

Frontiers in Immunology, 2019
The central paradigm of vaccination is to generate resistance to infection by a specific pathogen when the vacinee is re-exposed to that pathogen. This paradigm is based on two fundamental characteristics of the adaptive immune system, specificity and ...
Babita Agrawal
doaj   +4 more sources

Heterologous immune responses in health and disease

Инфекция и иммунитет, 2020
Immunological memory and tolerance represent major achievements and advantages of adaptive immunity. Organisms bearing adaptive immunity display prominent competitive advantages in the fight against infections.
A. P. Toptygina
doaj   +5 more sources

Editorial: Heterologous Immunity: Implications and Applications in Vaccines and Immunotherapies [PDF]

Frontiers in Immunology, 2020
Shakti Singh, Stephanie K. Yanow, Babita Agrawal   +2 more
doaj   +4 more sources

Heterologous immunity between viruses [PDF]

Immunological Reviews, 2010
Summary:  Immune memory responses to previously encountered pathogens can sometimes alter the immune response to and the course of infection of an unrelated pathogen by a process known as heterologous immunity. This response can lead to enhanced or diminished protective immunity and altered immunopathology.
Raymond M Welsh, Michael A Brehm, Liisa K Selin   +2 more
exaly   +4 more sources

Nontuberculous Mycobacteria and Heterologous Immunity to Tuberculosis. [PDF]

J Infect Dis, 2019
AbstractDevelopment of an improved tuberculosis (TB) vaccine is a high worldwide public health priority. Bacillus Calmette-Guerin (BCG), the only licensed TB vaccine, provides variable efficacy against adult pulmonary TB, but why this protection varies is unclear.
Shah JA, Lindestam Arlehamn CS, Horne DJ, Sette A, Hawn TR.   +4 more
europepmc   +4 more sources

Hybrid immunity strategies: heterologous vaccination combined with natural SARS-CoV-2 infection [PDF]

Frontiers in Medicine
The continuous evolution of SARS-CoV-2 poses a significant challenge to existing immune barriers, highlighting the limitations of single-modality immunization.
Yuan Huang, Xiaolu Zhang, Ruixia Miao, Jing Wang, Xuan Xi, Heng Pan, Yan Lu, Dehong Li   +7 more
doaj   +2 more sources

Heterologous Immunity and Persistent Murine Cytomegalovirus Infection. [PDF]

J Virol, 2017
ABSTRACT One's history of infections can affect the immune response to unrelated pathogens and influence disease outcome through the process of heterologous immunity. This can occur after acute viral infections, such as infections with lymphocytic choriomeningitis virus (LCMV) and vaccinia virus, where the pathogens are cleared ...
Che JW, Daniels KA, Selin LK, Welsh RM.
europepmc   +4 more sources

Heterologous immunity meets tissue-specific training [PDF]

Nature Reviews Immunology, 2016
Tracy Hussell describes a 2003 study by Chen et al. that pioneered the concept of heterologous immunity.
Tracy Hussell, Hussell Tracy
exaly   +3 more sources