Results 101 to 110 of about 214 (132)
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Plant Cell, Tissue and Organ Culture (PCTOC), 2011
Plant cyclopeptides are a large group of small molecule metabolites found in a wide variety of plants, including traditional Chinese medicinal plants. Many of the cyclopeptides have highly unusual structures and potent biological activities. However, the majority of the cyclopeptides have not been studied for their biosynthetic mechanisms.
Wenyan Xu +6 more
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Plant cyclopeptides are a large group of small molecule metabolites found in a wide variety of plants, including traditional Chinese medicinal plants. Many of the cyclopeptides have highly unusual structures and potent biological activities. However, the majority of the cyclopeptides have not been studied for their biosynthetic mechanisms.
Wenyan Xu +6 more
openaire +1 more source
International Immunopharmacology
Accumulating evidence implicates both the brain-spleen axis and the gut microbiota-brain axis in Alzheimer's disease (AD) pathogenesis. While our previous work demonstrated heterophyllin B (HB) rectifies splenic Th1/Th2 imbalance and ameliorates cognitive deficits in Aβ1-42-induced AD mice, its potential modulation of the vagus nerve-spleen circuit ...
Jiahui, Jiang +6 more
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Accumulating evidence implicates both the brain-spleen axis and the gut microbiota-brain axis in Alzheimer's disease (AD) pathogenesis. While our previous work demonstrated heterophyllin B (HB) rectifies splenic Th1/Th2 imbalance and ameliorates cognitive deficits in Aβ1-42-induced AD mice, its potential modulation of the vagus nerve-spleen circuit ...
Jiahui, Jiang +6 more
openaire +2 more sources
Plant Physiology and Biochemistry
As a popular medicinal plant, Pseudostellaria heterophylla has been attached to great importance in herbal medicine. Heterophyllin B (HB), isolated from P. heterophylla, is a strongly pharmacologically active cyclic peptide. However, the key enzymes that catalyze the HB biosynthesis remain unidentified.
Guoping, Shu +8 more
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As a popular medicinal plant, Pseudostellaria heterophylla has been attached to great importance in herbal medicine. Heterophyllin B (HB), isolated from P. heterophylla, is a strongly pharmacologically active cyclic peptide. However, the key enzymes that catalyze the HB biosynthesis remain unidentified.
Guoping, Shu +8 more
openaire +2 more sources
Analytical Letters, 2002
From the root of Pseudostellaria heterophylla a cyclopeptide, heterophyllin B, was isolated by high-speed countercurrent chromatography. Fused-silica capillary columns containing heterophyllin B as a main stationary phase component were prepared. The chromatographic selectivity of heterophyllin B showed toward aromatics.
L. M. Yuan +6 more
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From the root of Pseudostellaria heterophylla a cyclopeptide, heterophyllin B, was isolated by high-speed countercurrent chromatography. Fused-silica capillary columns containing heterophyllin B as a main stationary phase component were prepared. The chromatographic selectivity of heterophyllin B showed toward aromatics.
L. M. Yuan +6 more
openaire +1 more source
Tissue and Cell
Heterophyllin B (HB) is a cyclic peptide with anti-neoplastic effect on many cancers. However, its effect and mechanism of action in ovarian cancer cells are still unknown.The primary objective of this study was to assess the impact of HB on the proliferation of ovarian cancer (OC) cells and delve into the underlying mechanisms involved.We performed ...
Linyu, Shi +3 more
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Heterophyllin B (HB) is a cyclic peptide with anti-neoplastic effect on many cancers. However, its effect and mechanism of action in ovarian cancer cells are still unknown.The primary objective of this study was to assess the impact of HB on the proliferation of ovarian cancer (OC) cells and delve into the underlying mechanisms involved.We performed ...
Linyu, Shi +3 more
openaire +2 more sources
Study on the Interaction of Heterophyllin B and VEGFA, HMGB1 by Molecular Docking Simulation
Hans Journal of Biomedicine, 2021openaire +1 more source
Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Ca-A Cancer Journal for Clinicians, 2020Aaron J Grossberg +2 more
exaly