Results 121 to 130 of about 5,136 (212)

Ceftazidime/avibactam Improves the Antibacterial Efficacy of Polymyxin B Against Polymyxin B Heteroresistant KPC-2-Producing Klebsiella pneumoniae and Hinders Emergence of Resistant Subpopulation in vitro

Frontiers in Microbiology, 2019
Due to the increasing multidrug resistance and limited antibiotics, polymyxin B revived as the last resort for the treatment of carbapenemase-producing Klebsiella pneumoniae (CRKP).
Xingyan Ma, Yuting He, Xuegao Yu, Yimei Cai, Jianming Zeng, Jianming Zeng, Renxin Cai, Renxin Cai, Yang Lu, Yang Lu, Liang Chen, Cha Chen, Cha Chen, Bin Huang   +13 more
doaj   +1 more source

Heteroresistance to carbapenems in Acinetobacter baumannii [PDF]

Journal of Antimicrobial Chemotherapy, 2005
S, Pournaras, A, Ikonomidis, A, Markogiannakis, A N, Maniatis, A, Tsakris   +4 more
openaire   +2 more sources

The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing

Nature Communications
Antibiotic heteroresistance, characterized by rare resistant subpopulations of bacteria within a susceptible main population, is associated with treatment failure and often caused by tandem amplification of resistance genes. Here, we investigated how the
Sofia Jonsson, Andrei Guliaev, Brandon A. Berryhill, Dan I. Andersson, Hervé Nicoloff   +4 more
doaj   +1 more source

Vancomycin Heteroresistance in Methicillin-resistantStaphylococcus aureus, Taiwan

Emerging Infectious Diseases, 2004
To the Editor: In 1997, Hiramatsu and colleagues reported the first clinical isolate of methicillin-resistant Staphylococcus aureus (MRSA) showing reduced susceptibility to vancomycin (1). Soon thereafter, vancomycin-intermediate S. aureus (VISA) or heteroresistant VISA was reported to have disseminated in Japanese hospitals (2). In Taiwan, a survey of
Wang, Jiun-Ling, Tseng, Sung-Pin, Hsueh, Po-Ren, Hiramatsu, Keiichi   +3 more
openaire   +2 more sources

Indications of carbapenem resistance evolution through heteroresistance as an intermediate stage in Acinetobacter baumannii after carbapenem administration Indicações da evolução da resistência ao carbapenem através da heteroresistência como estágio intermediário no Acinetobacter baumannii após administração de carbapenem

Revista do Instituto de Medicina Tropical de São Paulo, 2009
We describe an in vivo evolution of an antimicrobial profile from susceptibility to full-resistance to carbapenems, with heteroresistance as an intermediate stage, in an Acinetobacter baumannii strain.
Silvana Vargas Superti, Daniela de Souza Martins, Juliana Caierão, Fabiana da Silva Soares, Taísa Prochnow, Alexandre Prehn Zavascki   +5 more
doaj   +1 more source

Widespread heteroresistance to antibiotics in Lactobacillus species

AbstractLactobacilli are prevalent members of the intestinal and reproductive tract microbiota of humans and other species. They are commonly used in probiotics and various food products due to their beneficial effects on human health. For example, these beneficial microbes are used to treat diarrhea caused by antibiotic therapy and are commonly given ...
Rivera-Rodriguez, Dormarie E., Busby, Chayse, Cervantes-Barragan, Luisa, Weiss, David S.   +3 more
openaire   +2 more sources

Detection of pyrazinamide heteroresistance in Mycobacterium tuberculosis

International Journal of Mycobacteriology, 2015
AbstractAimPyrazinamide (PZA) is a first-line key agent in the effective treatment of tuberculosis (TB), including PZA susceptible multidrug-resistant tuberculosis (MDR-TB). Occasionally, TB patients might have mixed infections with both drug-sensitive and -resistant strains. This is termed heteroresistance.
Mikaela Glader, Sven Hoffner, Jim Werngren   +2 more
openaire   +2 more sources

Progress in the Study of Polymyxin Heteroresistance Molecular Mechanisms

Xiehe Yixue Zazhi
Polymyxins, a class of cyclic peptide antibiotics, have become the last line of defense against gram-negative bacterial infections as the number of multidrug-resistant bacteria continues to rise.
LI Yanbing, ZHOU Menglan, XU Yingchun
doaj   +1 more source

Heteroresistant and nonheteroresistant methicillin-resistant Staphylococcus aureus [PDF]

Journal of Clinical Microbiology, 1987
P E, Varaldo, F, Biavasco, M P, Montanari   +2 more
openaire   +2 more sources

Genetic Evaluation of Heteroresistance among Carbapenem-Susceptible Clinical Isolates of Enterobacterales

Canadian Journal of Infectious Diseases and Medical Microbiology
Carbapenems currently serve as the last line of defense when treating serious infections caused by multidrug-resistant Enterobacterales species; however, heteroresistance of these species is thought to cause failure in the treatment with these broad ...
İpek Koçer, Mehmet Eri̇nmez, Yasemin Zer   +2 more
doaj   +1 more source