Results 11 to 20 of about 5,051 (197)

Investigation of voriconazole heteroresistance in clinical isolates of Trichosporon asahii from a multicenter study in China [PDF]

Microbiology Spectrum
Heteroresistance refers to the presence of subpopulations within seemingly homogeneous microbial cells that exhibit varying sensitivities to antifungal agents, potentially contributing to treatment failure.
Chenlu Liu, Qiaoying Gao, Yingxing Li, Jinhan Yu, Shuying Yu, Xinfei Chen, Xue Li, Yingchun Xu, Ying Zhao, Lina Guo   +9 more
doaj   +2 more sources

Heteroresistance is associated with mutations during low concentration of tigecycline therapy in multiple-resistant Klebsiella pneumoniae [PDF]

Annals of Clinical Microbiology and Antimicrobials
Background Heteroresistance can lead to treatment failure and has brought a rigorous challenge to clinical laboratories for detecting them. The aim of this study was to investigate the potential for tigecycline-susceptible Klebsiella pneumoniae (K ...
Qiaoyu Zhang, Linwen Zheng, Lirong Wen, Shanshan Li, Yuli Nie, Jiansen Chen   +5 more
doaj   +2 more sources

An Investigation of Colistin Heteroresistance in <i>Klebsiella pneumoniae</i> Isolates in Iran. [PDF]

Biomed Res Int
Background According to the World Health Organization 2024 bacterial priority pathogens list, carbapenem‐resistant Enterobacterales (CRE) were listed among the critical priority pathogens. Heteroresistance (i.e., a bacterial isolate that appears susceptible but harbors resistant subpopulations) represents a challenge in traditional laboratory testing ...
Rad ZR, Rad ZR, Goudarzi H, Goudarzi M, Javidi M, Sharahi JY, Kargar M, Hashemi A.   +7 more
europepmc   +2 more sources

Fluconazole Resistance and Heteroresistance in Cryptococcus spp.: Mechanisms and Implications [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
The reference methodology for evaluating antifungal susceptibility is based on determining the minimum inhibitory concentration (MIC), which is the lowest drug concentration capable of inhibiting fungal growth.
Izabela de Mesquita Bárcia Moreira, Naira Sulany Oliveira de Sousa, Juan Diego Ribeiro de Almeida, Robert Langlady Lira Rosas Filho, Katia Santana Cruz, Ani Beatriz Jackisch Matsuura, Márcia de Souza Carvalho Melhem, Érica Simplício de Souza, Hagen Frickmann, Marcus Vinícius Guimarães Lacerda, João Vicente Braga de Souza   +10 more
doaj   +2 more sources

Heterogeneous subpopulations in Escherichia coli strains acquire adaptive resistance to imipenem treatment through rapid transcriptional regulation [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionHeteroresistance is a well-known phenomenon contributing to treatment failure in bacterial infections. Previous research has traditionally linked it to genetic mechanisms, emphasizing fixed subpopulations with specific resistance mutations ...
YunTao Luo, Rong Xu, Bo Yuan, WeiHua Yang, YunHeng Zhou, Yuan Tian, QingZhong Wang   +6 more
doaj   +2 more sources

Analysis of β-lactams and Carbapenem Heteroresistance in Extra-intestinal Pathogenic Escherichia coli from Blood Samples in Iran

Journal of Medical Microbiology and Infectious Diseases, 2021
Introduction: Heteroresistance is the phenomenon wherein subpopulations of microbes exhibit a range of resistance to an antibiotic and are prevalent in a broad range of microorganisms.
Mohammad Taha Ebrahimi, Mohsen Nazari, Niloofar Mobarezpour, Hamed Afkhami, Sepideh Fereshteh   +4 more
doaj   +1 more source

Detection of Colistin Heteroresistance in Carbapenem-Resistant <i>Pseudomonas aeruginosa</i> Clinical Isolates in Iran. [PDF]

Int J Microbiol
Background Since antimicrobial resistance is a rising danger and a serious threat to the health of humans, recent studies have revealed that routine tests, such as minimum inhibitory concentration (MIC), are not enough to detect heteroresistance (HR) phenotype (i.e., phenotypic heterogeneity in antibiotic susceptibility in the identical bacterial ...
Rad ZR, Rad ZR, Goudarzi H, Goudarzi M, Pourdehghan P, Kargar M, Shams S, Hashemi A.   +7 more
europepmc   +2 more sources

Antibiotic Heteroresistance in Klebsiella pneumoniae

International Journal of Molecular Sciences, 2021
Klebsiella pneumoniae is one of the most common pathogens responsible for infections, including pneumonia, urinary tract infections, and bacteremias. The increasing prevalence of multidrug-resistant K. pneumoniae was recognized in 2017 by the World Health Organization as a critical public health threat.
Karolina Stojowska-Swędrzyńska, Adrianna Łupkowska, Dorota Kuczyńska-Wiśnik, Ewa Laskowska   +3 more
openaire   +2 more sources

Heteroresistance to clarithromycin and metronidazole in patients with a Helicobacter pylori infection: a systematic review and meta-analysis

Annals of Clinical Microbiology and Antimicrobials, 2022
Background Antimicrobial resistance of H. pylori can lead to treatment failure. Importantly, several studies have reported on heteroresistance, i.e. the presence of resistant and susceptible H. pylori populations in the same sample and/or a difference in
Ebrahim Kouhsari, Nourkhoda Sadeghifard, Arezoo Khadiv, Hojjat Sayadi, Taghi Amiriani, Sobhan Ghafourian, Hassan Valadbeigi, Marcela Krutova   +7 more
doaj   +1 more source

Ceftaroline-Heteroresistant Staphylococcus aureus [PDF]

Antimicrobial Agents and Chemotherapy, 2014
ABSTRACT Heteroresistance refers to the presence, within a large population of antimicrobial-susceptible microorganisms, of subpopulations with lesser susceptibilities. Ceftaroline is a novel cephalosporin with activity against methicillin-resistant Staphylococcus aureus (MRSA).
Stephanie N, Saravolatz, Hayley, Martin, Joan, Pawlak, Leonard B, Johnson, Louis D, Saravolatz   +4 more
openaire   +2 more sources