Structure of the Gq-coupled adhesion receptor ADGRL4
Adhesion G protein-coupled receptors (aGPCRs) are a 32-member family of Class B GPCRs that have diverse cellular roles including mechanosensation, cell-fate determination, neurodevelopment, immune function and tumour biology. ADGRL4 is upregulated in the
Qingchao Chen +6 more
doaj +1 more source
Novel Insights into Understanding the Molecular Dialogues between Bipolaroxin and the Gα and Gβ Subunits of the Wheat Heterotrimeric G-Protein during Host-Pathogen Interaction. [PDF]
Malviya D +15 more
europepmc +1 more source
Activation of phospholipase C beta4 by heterotrimeric GTP-binding proteins [PDF]
Transient transfection assays were used to determine how the activity of phospholipase C beta 4, which is preferentially expressed in retina, was regulated.
Jiang, Huiping +2 more
core
Heterotrimeric G Proteins Are Implicated in Gibberellin Induction of α-Amylase Gene Expression in Wild Oat Aleurone [PDF]
Huw Jones +5 more
openalex +1 more source
OsGGC2, Gγ Subunit of Heterotrimeric G Protein, Regulates Plant Height by Functionally Overlapping with DEP1 in Rice. [PDF]
Chaya G +5 more
europepmc +1 more source
D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways [PDF]
Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed specifically in the striatum, which participates in antipsychotic-induced tardive dyskinesia and in levodopa-induced dyskinesia. We
Axelrod, Jeffrey D. +10 more
core
The α subunit of the heterotrimeric G protein regulates mesophyll CO2 conductance and drought tolerance in rice. [PDF]
Zait Y, Ferrero-Serrano Á, Assmann SM.
europepmc +1 more source
Research Advances in Heterotrimeric G-Protein α Subunits and Uncanonical G-Protein Coupled Receptors in Plants. [PDF]
Liu Y +8 more
europepmc +1 more source
Dynamic Coupling and Allosteric Networks in the α Subunit of Heterotrimeric G Proteins [PDF]
Xin‐Qiu Yao +6 more
openalex +1 more source
Simulation of spontaneous G protein activation reveals a new intermediate driving GDP unbinding [PDF]
Activation of heterotrimeric G proteins is a key step in many signaling cascades. However, a complete mechanism for this process, which requires allosteric communication between binding sites that are ~30 Å apart, remains elusive.
Blumer, Kendall J +3 more
core +1 more source

