Results 91 to 100 of about 11,723 (175)

Small-molecule inhibitor of Gαo for GNAO1 encephalopathy. [PDF]

Biosci Rep
Larasati YA, Koval A, Katanaev VL.
europepmc   +1 more source

A complex interplay of various intracellular motifs determines G protein binding and activation of muscarinic receptors. [PDF]

Sci Rep
Kirchhofer SB, Jelinek V, Klingelhöfer K, Krett AL, Bünemann M.   +4 more
europepmc   +1 more source

G-protein regulatory network governs receptor internalization dynamics. [PDF]

Proc Natl Acad Sci U S A
Rowe JB, Pandey S, Mayer RA, Ludlam WG, Drube J, Inoue A, Hoffmann C, Martemyanov KA.   +7 more
europepmc   +1 more source

Non-canonical and constitutive activation of small GTPases: more than an exception to the rule? [PDF]

Biochem J
Kiers J, Hordijk PL.
europepmc   +1 more source

Targets for majority of drugs: G protein-coupled receptors - their structure and interaction with bioligands

, 1998
G protein-coupled receptors (GPCRs) are the most frequent targets for many drugs. They form the largest superfamily of integral membrane proteins, of which more than 1000 members have the following common features: (i) All GPCRs form 7 hydrophobic a ...
Pasenkiewicz-Gierula, M., Ciarkowski, J., Czaplewski, C.   +2 more
core  

Binding of the brain G protein G⍺_o to its potential effector RASA3 is promoted by Ca². [PDF]

J Biol Chem
Bell HAS, Olson AC, Gentile JE, Lam TT, Koelle MR.   +4 more
europepmc   +1 more source

In vitro activation of the NADPH oxidase by fluoride. Possible involvement of a factor activating GTP hydrolysis on Rac (Rac-GAP).

, 1996
International audienceThe possible mechanism of activation of the NADPH oxidase by fluoride was investigated in the cell-free system. It is shown that the stimulatory effect of fluoride is inhibited by guanosine 5'-O-(2-thiodiphosphate) (GDP[S]) and ...
Wölfl, J., Ligeti, E., Dagher, M. C., Geiszt, M., Fuchs, Alexandra   +4 more
core  

A unified mechanism for tubulin cofactors catalyzing α/β-tubulin biogenesis and degradation. [PDF]

Sci Adv
Taheri A, Ashaduzzaman M, Gill V, Eskin JA, Al-Bassam J.   +4 more
europepmc   +1 more source

Current Topics in Heterotrimeric GTP-binding Proteins. Regulation of G proteins by receptors.

Folia Pharmacologica Japonica, 1994
Hitoshi KUROSE, Taku NAGAO
openaire   +3 more sources

Identification of a small molecule that targets activator of G-protein signaling 8. [PDF]

J Physiol Sci
Hossain A, Yamamura A, Takahashi R, Iezaki T, Hayashi H, Hirano H, Osada H, Umezawa K, Sato M.   +8 more
europepmc   +1 more source