Revista Brasileira de Hematologia e Hemoterapia, 2012 Hereditary hemochromatosis (HH) is an autosomal recessive disorder classically related to HFE mutations. However, since 1996, it is known that HFE mutations explain about 80% of HH cases, with the remaining around 20% denominated non-HFE hemochromatosis.
Paulo Caleb Júnior de Lima Santos +5 more
doaj +5 more sources
Synergistic Contribution of HFE H63D Mutation to Secondary Polycythemia Pathogenesis at Moderate–High Altitude: A Retrospective Cohort Study [PDF]
DiagnosticsObjective: This study examined whether HFE H63D carriers living at moderate-to-high altitude have a stronger secondary polycythemia phenotype than non-carriers from the same region.
Tahir Alper Cinli, Ceren Alavanda
doaj +2 more sources
Diabetes in HFE Hemochromatosis [PDF]
Journal of Diabetes Research, 2017 Diabetes in whites of European descent with hemochromatosis was first attributed to pancreatic siderosis. Later observations revealed that the pathogenesis of diabetes in HFE hemochromatosis is multifactorial and its clinical manifestations are ...
James C. Barton, Ronald T. Acton
doaj +3 more sources
Molecular basis of HFE-hemochromatosis [PDF]
Frontiers in Pharmacology, 2014 Iron-overload disorders owing to genetic misregulation of iron acquisition are referred to as hereditary hemochromatosis (HH). The most prevalent genetic iron overload disorder in Caucasians is caused by mutations in the HFE gene, an atypical MHC class I
Maja eVujic Spasic
doaj +4 more sources
Effects of an Herbal Formulation Ethanolic Extract on Streptococcus pyogenes: Bactericidal Activity, Biofilm Control, and Interactions with Conventional Antibiotics [PDF]
PathogensStreptococcus pyogenes is a pathogen that causes skin infections worldwide. Currently, there is growing interest in herbal formulations as potential sources of antibacterial agents.
Rohana Dolee +9 more
doaj +2 more sources
Despite Genetic Iron Overload, Hfe-Hemochromatosis Mice Do Not Show Bone Loss
JBMR Plus, 2019 One of the most prevalent genetic iron overload disorders in Caucasians is caused by mutations in the HFE gene. Both HFE patients and Hfe‐mouse models develop a progressive accumulation of iron in the parenchymal cells of various tissues, eventually ...
Mubashir Ahmad +2 more
exaly +2 more sources
Hemochromatosis and Xeroderma Pigmentosum: Two (Un)Suspicious Neighbors
GE: Portuguese Journal of Gastroenterology, 2021 A 51-year-old woman, clinically diagnosed with Xeroderma pigmentosum (XP), showed abnormalities in liver enzymes, high ferritin and transferrin saturation levels, with ultrasonographic features of chronic liver disease, in addition to skin ...
Filipa Monte +5 more
doaj +1 more source
Advanced parametrical modelling of 24 GHz radar sensor IC packaging components [PDF]
Advances in Radio Science, 2011 This paper deals with the development of an advanced parametrical modelling concept for packaging components of a 24 GHz radar sensor IC used in automotive driver assistance systems. For fast and efficient design of packages for system-in-package modules
R. Kazemzadeh +4 more
doaj +1 more source
Primary Terminal Haemochromatosis in a 50 Year-Old Patient
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2021 Aim. A clinical description of end-stage hereditary haemochromatosis manifested with chronic alcohol abuse.Key points. A 50-yo patient referred with marked general weakness as a major complaint.
M. I. Gonik +7 more
doaj +1 more source
AlGaN/GaN high electron mobility transistor oscillator for high temperature and high frequency
Electronics Letters, 2021 A high‐temperature 2.1 GHz oscillator based on a AlGaN/GaN high electron mobility transistor (HEMT) is successfully designed, implemented, and characterised for the first time.
Paula Palacios +7 more
doaj +1 more source