Results 1 to 10 of about 1,272 (93)

Correlations of PTEN and ERG Immunoexpression in Prostate Carcinoma and Lesions Related to Its Natural History: Clinical Perspectives [PDF]

open access: yesCurrent Issues in Molecular Biology, 2023
Purpose: The aim of our study was to observe the associations between the ETS-related gene (ERG) and the phosphatase and tensin homolog gene (PTEN) immunoexpression in prostate cancer and related lesions and highlight the clinical significance of these ...
Olga Voulgari   +6 more
doaj   +2 more sources

The impact of zinc and testosterone co-treatment on tumourigenesis in prostate cancer: a novel model [PDF]

open access: yesBMC Cancer
Background Pre-clinical models play a key role in prostate cancer research, helping to understand the mechanism of the disease. The unavailability of suitable animal models in under-resourced areas, such as in sub-Saharan African (SSA) countries ...
Kofi Oduro Yeboah   +8 more
doaj   +2 more sources

Preliminary clinical practice of radical prostatectomy without preoperative biopsy [PDF]

open access: yesChinese Medical Journal
. Background:. At present, biopsy is essential for the diagnosis of prostate cancer (PCa) before radical prostatectomy (RP). However, with the development of prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET ...
Ranlu Liu   +13 more
doaj   +2 more sources

Clinical significance of high grade and low grade prostate intraepithelial neoplasia

open access: yesMedičnì Perspektivi, 2021
Such premalignant conditions of prostate cancer (PC) as prostate intraepithelial neoplasia (PIN) are classified between benign and malignant ones. Contemporary evidence wheather PIN develops malignancy is limited and (LGPIN) data present varied results.
M.P. Melnychuk
doaj   +1 more source

Implication of High Grade Intraepithelial Neoplasia in Adverse Pathology after Radical Prostatectomy

open access: yesPrague Medical Report, 2012
The implication of high grade prostatic intraepithelial neoplasia (HGPIN) to prostate cancer aggressiveness and prognosis is conflicted. The aim of the present study was to evaluate the role of HGPIN in prediction of adverse pathology in patients ...
Stavros Sfoungaristos, P. Perimenis
doaj   +1 more source

Foamy gland high-grade prostatic intraepithelial neoplasia on core biopsy and subsequent radical prostatectomy: An in depth case report of a rare variant

open access: yesHuman Pathology: Case Reports, 2017
A 69-year-old man underwent a robotic-assisted laparoscopic prostatectomy after a biopsy proven diagnosis of prostatic adenocarcinoma (PCa). Both the biopsy and the prostatectomy specimens revealed an organ-confined conventional PCa of Gleason score 3 ...
Paul Friedman, MD   +2 more
doaj   +1 more source

MiR-141-3p Relative Expression Level from FFPE Samples as Biomarker of Prostate Adenocarcinoma Carcinogenesis in Yogyakarta, Indonesia

open access: yesIndonesian Journal of Medical Laboratory Science and Technology, 2022
Globally, prostate cancer (PCA) is the second leading cause of male cancer-associated mortality. Micro-RNAs (miRNAs) are small non-coding RNAs considered promising biomarkers for diagnosis, prognosis, and treatment options.
Sari Eka Pratiwi   +7 more
doaj   +1 more source

High grade intraepithelial neoplasia of prostate is associated with values of prostate specific antigen related parameters intermediate between prostate cancer and normal levels

open access: yesBiomolecules & Biomedicine, 2011
High grade prostatic intraepithelial neoplasia (HGPIN) is widely regarded as the precancerous. The aim of this study was to determine PSA related parameters in patients with initial PSA values 2-10 ng/mL and diagnosis of HGPIN without finding carcinoma ...
Nermina Obralic, Benjamin Kulovac
doaj   +1 more source

Overexpression of MiR-155-5p and increased number of macrophage population in precancerous prostatic disease

open access: yesHealth Science Journal of Indonesia, 2020
Latar Belakang: Gangguan regulasi mikroRNA(miR) dan inflamasi kronik dapat mengubah tumor menjadi karsinoma dan kanker dengan metastasis melalui perubahan seluler dan genomik. Lesi prekanker memiliki peluang 33,3 persen menjadi kanker.
Rachma Greta Putri   +6 more
doaj   +1 more source

Outcomes of prostate atypical small acinar proliferation and high-grade prostate intraepithelial neoplasm patients

open access: yesUrological Science, 2018
Objective: Atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two pathological findings occasionally noted in prostate biopsies.
Sheng-Yung Tung   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy