Expression of ERG protein, a prostate cancer specific marker, in high grade prostatic intraepithelial neoplasia (HGPIN): lack of utility to stratify cancer risks associated with HGPIN [PDF]
BJU International, 2012 Study Type – Diagnosis (cohort) Level of Evidence 2b What's known on the subject? and What does the study add? High grade prostatic intraepithelial neoplasia is a pre‐malignant lesion to prostate cancer and ...
Huiying, He +6 more
openaire +2 more sources
Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice [PDF]
, 2013 A role for microbes has been suspected in prostate cancer but difficult to confirm in human patients. We show here that a gastrointestinal (GI) tract bacterial infection is sufficient to enhance prostate intraepithelial neoplasia (PIN) and microinvasive ...
A Peled +43 more
core +11 more sources
Diagnostic utility of α-methylacyl CoA racemase (P504S) & HMWCK in morphologically difficult prostate cancer [PDF]
, 2010 Background To evaluate the diagnostic utility of alpha-methylacyl CoA racemase (P504S) & HMWCK (34beta E12) in morphologically difficult prostate cancer.
K Kumaresan +5 more
core +1 more source
Predicting prostate biopsy outcome: Prostate health index (phi) and prostate cancer antigen 3 (PCA3) are useful biomarkers [PDF]
, 2012 Indication for prostate biopsy is presently mainly based on prostate-specific antigen (PSA) serum levels and digital-rectal examination (DRE). In view of the unsatisfactory accuracy of these two diagnostic exams, research has focused on novel markers to ...
A. D. Carlo +13 more
core +1 more source
Clinical Pathology, 2020 Prostate intraepithelial neoplasia is described as a precursor lesion to prostatic adenocarcinoma. High-grade prostate intraepithelial neoplasia (HGPIN) is classified as both grade 2 and 3 prostate intraepithelial neoplasia due to inconsistency between ...
Najla Aldaoud +5 more
doaj +1 more source
Men's Health Journal, 2021 Introduction: To report the prevalence of various prostate lesions in the general population through cadaver prostates and to determine the interobserver variability for reporting high-grade lesions of the prostate.
Rachna Gulati +4 more
doaj +1 more source
Journal of the Egyptian National Cancer Institute, 2017 Caveolin-1 may play a role in cancer development and progression. The aim was to record the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high grade prostatic intraepithelial neoplasia (HGPIN) and prostatic carcinoma ...
Dareen A. Mohammed, Duaa S. Helal
doaj +1 more source
Activation of β‐Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration [PDF]
The Prostate, 2008 AbstractBACKGROUNDThe role of Wnt/β‐Catenin signaling in embryogenesis and carcinogenesis has been extensively studied in organs such as colon, lung and pancreas, but little is known about Wnt/β‐Catenin signaling in the prostate. Although stabilizing mutations in APC and β‐Catenin are rare in primary prostate tumors, recent studies suggest that ...
Xiuping, Yu +8 more
openaire +2 more sources
Translationally controlled tumor protein in prostatic adenocarcinoma: correlation with tumor grading and treatment-related changes [PDF]
, 2015 12Prostate cancer is the second leading cause of cancer-related death. The androgen deprivation therapy is the standard treatment for advanced stages. Unfortunately, virtually all tumors become resistant to androgen withdrawal.
Alessandro Ginori +11 more
core +3 more sources
Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]
, 2006 The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen +5 more
core +1 more source