Results 31 to 40 of about 2,707 (196)

Production of a soluble and functional recombinant apolipoproteinD in the Pichia pastoris expression system [PDF]

, 2016
ApolipoproteinD (ApoD) is a human glycoprotein from the lipocalin family. ApoD contains a conserved central motif of an 8-stranded antiparallel β-sheet, which forms a beta-barrel that can be used for transport and storage of diverse hydrophobic ligands ...
Armanmehr, S., Kalhor, H.R., Tabarraei, A.   +2 more
core   +1 more source

Immunohistochemical analysis of ezrin-radixin-moesin-binding phosphoprotein 50 in prostatic adenocarcinoma

BMC Urology, 2011
Background Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) is an adapter protein which has been shown to play an active role in a wide variety of cellular processes, including interactions with proteins related to both tumor suppression and ...
Chandran Uma R, Becich Michael J, Bartholow Tanner L, Parwani Anil V   +3 more
doaj   +1 more source

Different clinical significance of ASAP/HGPIN pattern in systematic vs. MRI‑US fusion guided prostate biopsy

Experimental and Therapeutic Medicine, 2020
Atypical small acinar proliferation (ASAP) and high grade intraepithelial neoplasia (HGPIN) patterns identified at prostate biopsy yield an important clinical significance, their presence signaling an increased likelihood of future oncological development or underdiagnosed PCa.
Iulia, Andras, Teodora, Telecan, Dana, Crisan, Emanuel, Cata, Pierre, Kadula, David, Andras, Maria, Bungardean, Ioan, Coman, Nicolae, Crisan   +8 more
openaire   +3 more sources

Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer [PDF]

, 2016
Prostate cancer (CaP) is the most common adult male cancer in the developed world. The paucity of biomarkers to predict prostate tumor biology makes it important to identify key pathways that confer poor prognosis and guide potential targeted therapy ...
Adams, David J., Ahmad, Imran, Edwards, Joanne, Galbraith, Laura, Hedley, Ann, Leung, Hing Y., Loveridge, Carolyn, Markert, Elke, Mui, Ernest, Patel, Rachana, Repiscak, Peter, Rust, Alistair G., Salji, Mark, Sansom, Owen J., Tan, Ee Hong, van der Weyden, Louise   +15 more
core   +1 more source

The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer [PDF]

, 2010
Background Dietary or therapeutic interventions to counteract the loss of PTEN expression could contribute to the prevention of prostate carcinogenesis or reduce the rate of cancer progression.
Maria H Traka, Caroline A Spinks, Joanne F Doleman, Antonietta Melchini, Richard Y Ball, Robert D Mills, Richard F Mithen   +6 more
core   +1 more source

Risk of prostate cancer after detection of isolated high-grade prostatic intraepithelial neoplasia (HGPIN) on extended core needle biopsy: a UK hospital experience

BMC Urology, 2009
Background High-grade prostatic intraepithelial neoplasia (HGPIN) is a precursor lesion to prostate cancer (CaP). UK-based studies examining the occurrence of isolated HGPIN and subsequent risk of CaP are lacking.
Blades Rosemary A, Ragavan Narasimhan, Nicholson Caroline M, Singh Paras B, Martin Francis L, Matanhelia Shyam S   +5 more
doaj   +1 more source

Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing [PDF]

, 2011
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Aberrant DNA methylation plays a pivotal
Beltran, L, Berney, DM, Brentnall, AR, Cuzick, J, Kim, DC, Kudahetti, SC, Lorincz, AT, Lu, YJ, Mao, XY, Shaw, GL, Thorat, MA, Vasiljevic, N, Wu, KQ, Xue, LY, Yu, YW   +14 more
core   +2 more sources

Detection of TMPRSS2 : ERG fusion gene in circulating prostate cancer cells [PDF]

, 2008
Creative Commons Attribution-NonCommercial-Share Alike 3.0 license (CC BY-NC SA)Aim: To investigate the existence of TMPRSS2:ERG fusion gene in circulating tumor cells (CTC) from prostate cancer patients and its potential in monitoring tumor metastasis ...
Bryan D. Young, Dan Berney, David M. Prowse, Greg Shaw, Jemal A, Lin B, Patricia Purkis, Pelkey TJ, R. Tim D. Oliver, Sakunthala C. Kudahetti, Saname Kia, Sharon Y. James, Theodora Tsigani, Ulbright TM., Winnes M, Xueying Mao, Yong-Jie Lu   +16 more
core   +1 more source

ZEB1 is Negatively Correlated with E-Cadherin in Prostatic Anomaly Tissue

MCBS (Molecular and Cellular Biomedical Sciences), 2022
Background: Prostatic anomalies are common in tumor or infection condition. The enlargement of prostate gland affects the epithelial cell polarity that involves epithelial-mesenchymal transition (EMT).
Sari Eka Pratiwi, Sri Nuryani Wahyuningrum, Rachmagreta Perdana Putri, Danarto Danarto, Didik Setyo Heriyanto, Nur Arfian, Sofia Mubarika Haryana, Indwiani Astuti   +7 more
doaj   +1 more source

Statin use linked with a decrease in the conversion from high-grade prostatic intraepithelial neoplasia (HGPIN) to prostate cancer [PDF]

Carcinogenesis, 2018
The roles of obesity, metabolic dysregulation and systemic inflammation to advance prostate carcinogenesis are unclear. This study investigates metabolic and inflammatory factors in the transition from high-grade prostatic intraepithelial neoplasia (HGPIN) to prostate cancer (PC).
Jay H, Fowke, Saundra S, Motley
openaire   +2 more sources