Enhanced virus reconstitution of human herpesvirus 6A (HHV-6A)
Abstract Background Human herpesvirus 6A (HHV-6A) is a member of the betaherpesvirus family and is associated with neurotropic diseases. Despite its clinical significance, HHV-6A research has been hampered by challenges in the generation of recombinant viruses.
Reich, Jana +12 more
openaire +2 more sources
GP96 interacts with HHV-6 during viral entry and directs it for cellular degradation.
CD46 and CD134 mediate attachment of Human Herpesvirus 6A (HHV-6A) and HHV-6B to host cell, respectively. But many cell types interfere with viral infection through rapid degradation of viral DNA.
Bhupesh K Prusty +4 more
doaj +1 more source
Type specific Real time PCR for detection of human herpes virus 6 in schizophrenia and bipolar patients: A case control study [PDF]
Background: Schizophrenia (SC) and bipolar disorder (BD) are among the most devastating diseases worldwide. There are several lines of evidence suggesting that viruses may play significant roles in the etiology of these mental disorders.
Ahamadkhaniha, H.R. +7 more
core +1 more source
HHV‐6A infection of endometrial epithelial cells affects immune profile and trophoblast invasion
AbstractProblemWe first reported human herpesvirus (HHV)‐6A DNA presence in 43% of endometrial cells from women with idiopathic infertility, whereas no fertile control women harbored the virus. We investigated the effect of HHV‐6A infection on the immunological status of the endometrium.Method of studyEndometrial biopsies, uterine flushing, and whole ...
Daria BORTOLOTTI +6 more
openaire +3 more sources
Epstein‐Barr Virus Infection at Single‐Cell Resolution
ABSTRACT Epstein‐Barr virus (EBV) infection has been studied at single‐cell resolution for six decades and counting. Such investigations can reveal virus‐host interactions and their dependence on viral strain, cellular niche, infection program, immune response regulation, and time.
Elliott D. SoRelle
wiley +1 more source
Purification of infectious human herpesvirus 6A virions and association of host cell proteins
Background Viruses that are incorporating host cell proteins might trigger autoimmune diseases. It is therefore of interest to identify possible host proteins associated with viruses, especially for enveloped viruses that have been suggested to play a ...
Garoff Henrik +4 more
doaj +1 more source
The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu +2 more
wiley +1 more source
The aim of this study was to compare the performance of the newly developed SMG HHV-6 Q Real-Time PCR Kit (SMG assay) with the RealStar HHV-6 PCR Kit (RealStar assay).
Tae Yeul Kim +12 more
doaj +1 more source
Drug‐induced hypersensitivity syndrome followed by exacerbation of Crohn's disease
Pediatric Investigation, EarlyView.
Mei Kamidani +10 more
wiley +1 more source
Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu +3 more
wiley +1 more source

