Results 31 to 40 of about 2,937 (141)

Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay. [PDF]

PLoS ONE, 2014
The human herpesviruses HHV-6A and HHV-6B have been associated with various neurologic disorders partly due to the detection of elevated viral DNA levels in patients compared to controls.
Emily C Leibovitch, Giovanna S Brunetto, Breanna Caruso, Kaylan Fenton, Joan Ohayon, Daniel S Reich, Steven Jacobson   +6 more
doaj   +1 more source

High incidence and viral load of HHV-6A in a multi-centre kidney transplant cohort

Frontiers in Transplantation, 2023
Human herpesvirus 6 (HHV-6) is a common opportunistic pathogen in kidney transplant recipients. Two distinct species of HHV-6, HHV-6A and HHV-6B, have been identified, of which the latter seems to be dominant. However, it is unclear whether they increase
Arturo Blazquez-Navarro, Arturo Blazquez-Navarro, Toralf Roch, Toralf Roch, Patrizia Wehler, Patrizia Wehler, Sviatlana Kaliszczyk, Sviatlana Kaliszczyk, Chris Bauer, Constantin Thieme, Kamil S. Rosiewicz, Ulrik Stervbo, Ulrik Stervbo, Moritz Anft, Petra Reinke, Christian Hugo, Panagiota Zgoura, Richard Viebahn, Timm Westhoff, Michal Or-Guil, Nina Babel, Nina Babel   +21 more
doaj   +1 more source

Association Between Plasma SITH-1 Antibody Titers and Treatment Trajectory of Treatment-Resistant Depression. [PDF]

Neuropsychopharmacol Rep
This study investigated whether SITH‐1, a latent HHV‐6B protein that promotes neuroinflammation, is associated with the clinical trajectory of treatment‐resistant depression (TRD). We demonstrated significantly elevated SITH‐1 titers and a correlation with the number of depressive episodes, suggesting that SITH‐1 may serve as a novel biomarker for TRD.
Mori K, Kodaka F, Ishii J, Oka N, Kondo K, Kito S.   +5 more
europepmc   +2 more sources

Inhibition of p53-dependent, but not p53-independent, cell death by U19 protein from human herpesvirus 6B.

PLoS ONE, 2013
Infection with human herpesvirus (HHV)-6B alters cell cycle progression and stabilizes tumor suppressor protein p53. In this study, we have analyzed the activity of p53 after stimulation with p53-dependent and -independent DNA damaging agents during HHV ...
Emil Kofod-Olsen, Janni M L Møller, Mariane H Schleimann, Bettina Bundgaard, Rasmus O Bak, Bodil Øster, Jacob G Mikkelsen, Ted Hupp, Per Höllsberg   +8 more
doaj   +1 more source

Temporal lobe epilepsy associated with human herpes virus 6

Acta Epileptologica, 2021
Human herpes virus 6 (HHV-6) is a ubiquitous and most common pathogen that affects humans. Human herpes virus 6B (HHV-6B) is a wide spread human herpesvirus that infects most people when they are children, establishes latent infections in the central ...
Jiaqi Wang, Jinmei Li
doaj   +1 more source

β-Herpesviruses in Febrile Children with Cancer

Emerging Infectious Diseases, 2008
We conducted a cross-sectional study of β-herpesviruses in febrile pediatric oncology patients (n = 30), with a reference group of febrile pediatric solid-organ transplant recipients (n = 9).
Stephanie Yee-Guardino, Kate Gowans, Belinda Yen-Lieberman, Pamela Berk, Debra Kohn, Fu-Zhang Wang, Lara Danziger-Isakov, Camille Sabella, Sarah Worley, Philip E. Pellett, Johanna Goldfarb   +10 more
doaj   +1 more source

Comparison of Droplet Digital PCR and Metagenomic Next-Generation Sequencing Methods for the Detection of Human Herpesvirus 6B Infection Using Cell-Free DNA from Patients Receiving CAR-T and Hematopoietic Stem Cell Transplantation

Infection and Drug Resistance, 2022
Jiao Meng,1,* Hongyan Ji,2,* Liting Chen,2 Aichun Liu1 1Hematology Department, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, People’s Republic of China; 2Department of Hematology, Tongji Hospital, Tongji Medical ...
Meng J, Ji H, Chen L, Liu A
doaj  

Human herpesvirus 6B (HHV-6B) detection and genome-wide host expression profiles implicate HHV-6B as a pulmonary pathogen after hematopoietic cell transplantation

, 2023
Abstract Limited understanding of the immunopathogenesis of human herpesvirus 6B (HHV-6B) has prevented its acceptance as a pulmonary pathogen after hematopoietic cell transplantation (HCT). We conducted a prospective multicenter study of patients undergoing bronchoalveolar lavage (BAL) for pneumonia after allogeneic HCT.
Joshua Hill, Yeon Joo Lee, Lisa Vande Vusse, Hu Xie, E Chung, Alpana Waghmare, Guang-Shing Cheng, Haiying Zhu, Meei-Li Huang, Geoffrey Hill, Keith Jerome, Wendy Leisenring, Danielle Zerr, Sina Gharib, Sanjeet Dadwal, Michael Boeckh   +15 more
openaire   +1 more source

Structural basis for the interaction of human herpesvirus 6B tetrameric glycoprotein complex with the cellular receptor, human CD134.

PLoS Pathogens, 2020
A unique glycoprotein is expressed on the virus envelope of human herpesvirus 6B (HHV-6B): the complex gH/gL/gQ1/gQ2 (hereafter referred to as the HHV-6B tetramer).
Mitsuhiro Nishimura, Bernadette Dian Novita, Takayuki Kato, Lidya Handayani Tjan, Bochao Wang, Aika Wakata, Anna Lystia Poetranto, Akiko Kawabata, Huamin Tang, Taiki Aoshi, Yasuko Mori   +10 more
doaj   +1 more source

HHV-6B is frequently found in the gastrointestinal tract in kidney transplantation patients. [PDF]

Transplant international : official journal of the European Society for Organ Transplantation, 2012
In immunosuppressed patients human herpesvirus 6 (HHV-6) reactivations are common. The aim of the study was to determine to which extent HHV-6 can be found in the gastrointestinal tract in kidney transplant recipients and in patients on chronic dialysis. The HHV-6 and cytomegalovirus (CMV) examinations were performed on gastro duodenal and colon biopsy
Lempinen, Marko, Halme, Leena, Arola, Johanna, Honkanen, Eero, Salmela, Kaija, Lautenschlager, Irmeli   +5 more
  +5 more sources