Results 131 to 140 of about 243,805 (237)

ORBIT‐AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age‐Related Macular Degeneration in Multi‐Cohorts

Advanced Science, EarlyView.
Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui, Dejia Wen, Patrick Yu‐Wai‐Man, Xiaorong Li   +3 more
wiley   +1 more source

RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine

Advanced Science, EarlyView.
RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López‐Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, Zheng Sun, Leng Han, Dongyin Guan   +12 more
wiley   +1 more source

Hi-C calibration by chemically induced chromosomal interactions. [PDF]

EMBO Rep
Li Y, Fischer CWA, Zou F, Du M, Bai L.
europepmc   +1 more source

Hi-C-Daze Regimen [PDF]

, 2020
openaire   +1 more source

A Bright Ratiometric Dipyrene Probe for Functional Imaging of Condensate Microenvironments in Living Cells

Advanced Science, EarlyView.
Ratiometric dipyrene imaging resolves monomer (M) and excimer (E) channels and computes pixel‐wise E/M maps within biomolecular condensates, yielding physicochemical fingerprints shaped by coupled polarity‐related solvation and microviscosity. These spatial fingerprints enable quantitative phenotyping of cellular states, exemplified by separation of ...
Koki Matsumoto, Sora Kitai, Yoshio Nishiyama, Shogo Amemori, Kei Makiyama, Dini Kurnia Ikliptikawati, Kentaro Ohira, Yuta Kozuka, Maho Tobita, Shih‐Cheng Chen, Chien‐Hung Yu, Wei‐Min Liu, De‐Chen Lin, Motohiro Mizuno, Kazuma Ogawa, Koichi Ogami, Kenji Takahashi, Hiroshi I. Suzuki, Richard W. Wong, Takahiro Soeta, Masaharu Hazawa   +20 more
wiley   +1 more source

Physics-Based Modeling of Sparse Single-Cell Hi-C Uncovers Structural and Epigenetic Variability. [PDF]

Int J Mol Sci
Vercellone F, Kundu S, Esposito A, Chiariello AM, Conte M, Abraham A, Fontana A, Di Pierno F, Guha S, Di Carluccio C, Olimpo M, Nicodemi M, Casale FP, Bianco S.   +13 more
europepmc   +1 more source

Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors

Advanced Science, EarlyView.
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang, Qian Cheng, Ziyi Wang, Jianwen Wei, Qun Guan, Huazhong Yu, Qingwen Zhang, Caixia Yin, Ruibing Wang   +8 more
wiley   +1 more source

Benchmarking Hi-C scaffolders using reference genomes and de novo assemblies. [PDF]

Genome Biol
Sur A, Noble WS, Myler PJ.
europepmc   +1 more source

In‐Situ Constructed Cations for 2D/3D Perovskite Heterostructure for Stable and Efficient Photovoltaics

Advanced Science, EarlyView.
An in‐situ spacer‐cation construction strategy is developed by inducing strong hydrogen bonding between n‐hexyl phosphonic acid (HPA) and FA+, forming a stable N‐type 2D/3D perovskite heterostructure. This approach suppressed defect formation, promoted electron transport, and improved intrinsic stability, delivering 26.32% PCE, excellent operational ...
Min Liu, Quanwen You, Licheng Liu, Xinbo Shi, Zhen Wang, Bo Wu, Zhengchi Yang, Guofu Zhou, Jun‐Ming Liu, Jinwei Gao, Yue Jiang   +10 more
wiley   +1 more source

Metagenomic Hi‑C Protocols for Viral Genome Binning, Taxonomic Annotation, and Interaction Network Visualization. [PDF]

Curr Protoc
Du Y, Wang Y, Sun F.
europepmc   +1 more source