Results 141 to 150 of about 14,864,540 (284)

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

Advanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang, Ilya Pyatnitskiy, Yanshu Shi, Kai Wing Kevin Tang, Yi Xie, Sihan Yu, Thomas Wynn, Xiangping Liu, Ju‐Chun Hsieh, Jinmo Jeong, Weilong He, Brinkley Artman, Anakaren Romero Lozano, Xi Shi, Arjun Sangani, Lief E Fenno, Samantha Santacruz, Banglin Chen, Huiliang Wang   +18 more
wiley   +1 more source

DeCGR: an interactive toolkit for deciphering complex genomic rearrangements from Hi-C data

BMC Genomics
Background Complex genomic rearrangements (CGRs) drive the restructuring of chromatin architecture, resulting in significant interactions among rearranged fragments, visible as anomalous interaction blocks in chromatin contact maps generated by ...
Junping Li, Minghui Sun, Yusen Ye, Lin Gao   +3 more
doaj   +1 more source

BEKVAEM: INTEGRATIVE DATA EXPLORER FOR HI-C DATA

Journal of Bioinformatics and Genomics, 2019
Motivation: The browser-based visualization of Hi-C contact maps alongside complementary data tracks is a computationally challenging task and requires an efficient software implementation to run on small clients.
Андреас Хофманн, Ян Мюггенбург, Фредерик Кремазы, Дитер Хеерманн   +3 more
doaj   +1 more source

Designed Lewis Acid–Base Passivation for High Performance Perovskite Solar Cells

Advanced Functional Materials, EarlyView.
ABSTRACT Silicon's high cost and long energy payback time remain major barriers to the global expansion of solar power. In contrast, metal–halide perovskites offer abundant, solution‐processable absorbers, and have achieved efficiencies of 25%–30%, positioning them as strong competitors to silicon.
Afna Manaf, Hiba Shahulhameed, Bhabani Sankar Swain, Shengzhong (Frank) Liu, Adel Najar   +4 more
wiley   +1 more source

Hi-C protocol v1

Hi-C protocol for ESC DE differentiation time course.
Renhe Luo, Michael Beer, Danwei Huangfu
openaire   +1 more source

Integration of chromosome conformation and gene expression networks reveals regulatory mechanisms in triple negative breast cancer

Frontiers in Cell and Developmental Biology
IntroductionTriple-negative breast cancer (TNBC) accounts for twelve percent of all breast cancer cases, with a survival rate around ten percent lower than ER+/PR+ positive breast cancers.
Helena Reyes-Gopar, Helena Reyes-Gopar, Helena Reyes-Gopar, Keila Adonai Pérez-Fuentes, Matthew L. Bendall, Enrique Hernández-Lemus, Enrique Hernández-Lemus   +6 more
doaj   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Hi-C and RNA-chromatin interactions for lncRNA ENSG00000272462.

(A) The top track shows the genomic location of the interaction, followed by tracks showing the Hi-C annotated interactions between lncRNA ENSG00000272462 and its candidate target genes in different cell types.
Imad Abugessaisa (627440), Yasushi Okazaki (3100), Josée Dostie (262897), Takeya Kasukawa (3041), Michiel J. L. de Hoon (11434447), Chikashi Terao (137128), Jordan A. Ramilowski (2259964), Lisa J. Strug (8293947), Chung Chau Hon (4520500), Jessica Severin (178475), Andrey I. Sigorskikh (18510105), Howard Y. Chang (215450), Michael M. Hoffman (5846618), Masayoshi Itoh (15728), Ken Yagi (246069), Chi Wai Yip (15068455), Mickaël Mendez (3864016), Piero Carninci (3015), Ivan V. Kulakovskiy (7592957), Saumya Agrawal (3441386), Tanvir Alam (638619), Kayoko Yasuzawa (18510108), Jay W. Shin (9030986), Vsevolod J. Makeev (7592954), Juha Kere (11900), Naoto Kondo (32868), Masaru Koido (14059995), Andrey Buyan (18510102), Yunjing Li (644191)   +28 more
core   +1 more source

Jo-Hi/TestWorkFlow: Change of Analyze Particles

, 2019
<p>The parameter settings for Analyze Particles were changed. Following changes were made: size: 10-infinity; create a new window showing outlines; display the results; clear results and fill holes.</p ...
Jo-Hi
core   +1 more source