Results 11 to 20 of about 34,892 (283)

Hypoxia Conditioning for High-Altitude Pre-acclimatization [PDF]

Journal of Science in Sport and Exercise, 2022
Abstract Purpose Main purposes of pre-acclimatization by hypoxia conditioning (HC) are the prevention of high-altitude illnesses and maintenance of aerobic exercise performance. However, robust evidence for those effects or evidence-based guidelines for exposure strategies, including recommendations to ensure safety, are
Martin Burtscher, Grégoire P. Millet, Johannes Burtscher   +2 more
openaire   +2 more sources

Ibuprofen Blunts Ventilatory Acclimatization to Sustained Hypoxia in Humans. [PDF]

, 2016
Ventilatory acclimatization to hypoxia is a time-dependent increase in ventilation and the hypoxic ventilatory response (HVR) that involves neural plasticity in both carotid body chemoreceptors and brainstem respiratory centers.
Antonova, Julie, Basaran, Kemal Erdem, Ellis, Erika, Ho, Baran, Hopkins, Susan R, Powell, Frank L, Villongco, Michael, Zarndt, Rachel   +7 more
core   +6 more sources

Curcumin induces apoptosis in human hepatocellular carcinoma cells by decreasing the expression of STAT3/VEGF/HIF-1α signaling

Open Life Sciences, 2023
Curcumin is the most abundant derivative of turmeric rhizome. Although studies have proved that curcumin could inhibit the growth of tumors, its specific molecular mechanism has not yet been fully elucidated.
Wang Xiaoping, Tian Yu, Lin Huanping, Cao Xiaolan, Zhang Zhendong   +4 more
doaj   +1 more source

Association of SLC11A1 Polymorphisms With Tuberculosis Susceptibility in the Chinese Han Population

Frontiers in Genetics, 2022
Tuberculosis (TB) is an important health issue in the world. Although the relation of SLC11A1 polymorphisms with TB risk has been extensively studied, it has not been reported in the northwest Chinese Han population.
Baoping Hu, Baoping Hu, Baoping Hu, Baoping Hu, Yuhe Wang, Yuhe Wang, Yuhe Wang, Yuhe Wang, Zhongtao Wang, Xue He, Xue He, Xue He, Li Wang, Li Wang, Li Wang, Dongya Yuan, Dongya Yuan, Dongya Yuan, Yongjun He, Yongjun He, Yongjun He, Tianbo Jin, Tianbo Jin, Tianbo Jin, Shumei He, Shumei He, Shumei He   +26 more
doaj   +1 more source

Effect of Sleep Quality on Anxiety and Depression Symptoms among College Students in China’s Xizang Region: The Mediating Effect of Cognitive Emotion Regulation

Behavioral Sciences, 2023
Background: While the exact mechanisms are not fully understood, there are significant links between sleep quality, anxiety, depressive symptoms, and cognitive emotion regulation.
Yingting Wang, Zixuan Guang, Jinjing Zhang, Lixin Han, Rongqiang Zhang, Yichun Chen, Qi Chen, Zhenjia Liu, Yuan Gao, Ruipeng Wu, Shaokang Wang   +10 more
doaj   +1 more source

Relationships Between Chemoreflex Responses, Sleep Quality, and Hematocrit in Andean Men and Women. [PDF]

, 2020
Andean highlanders are challenged by chronic hypoxia and many exhibit elevated hematocrit (Hct) and blunted ventilation compared to other high-altitude populations.
Anza-Ramirez, Cecilia, Corante, Noemi, DeYoung, Pamela N, Djokic, Matea A, Gaio, Eduardo, Gilbertson, Dillon, Heinrich, Erica C, Macarlupu, Jose L, Malhotra, Atul, Orr, Jeremy E, Powell, Frank L, Simonson, Tatum S, Villafuerte, Francisco C, Vizcardo-Galindo, Gustavo   +13 more
core   +1 more source

Tibetan medicine salidroside improves host anti-mycobacterial response by boosting inflammatory cytokine production in zebrafish

Frontiers in Pharmacology, 2022
The treatment for tuberculosis (TB), especially multidrug-resistant TB (MDR-TB), has a prolonged cycle which can last up to a year. This is partially due to the lack of effective therapies.
Shumei He, Hongyan Fan, Hongyan Fan, Bin Sun, Meipan Yang, Hongxu Liu, Hongxu Liu, Jianwei Yang, Jianwei Yang, Jianxin Liu, Jianxin Liu, Sizhu Luo, Sizhu Luo, Zihan Chen, Zihan Chen, Jing Zhou, Jing Zhou, Lu Xia, Shulin Zhang, Shulin Zhang, Bo Yan   +20 more
doaj   +1 more source

Hypoxia and Inflammation: Insights From High-Altitude Physiology [PDF]

Frontiers in Physiology, 2021
The key regulators of the transcriptional response to hypoxia and inflammation (hypoxia inducible factor, HIF, and nuclear factor-kappa B, NF-κB, respectively) are evolutionarily conserved and share significant crosstalk. Tissues often experience hypoxia and inflammation concurrently at the site of infection or injury due to fluid retention and immune ...
Pham, Kathy, Parikh, Keval, Heinrich, Erica C   +2 more
openaire   +5 more sources

High-altitude Hypoxia Influences the Activities of the Drug-Metabolizing Enzyme CYP3A1 and the Pharmacokinetics of Four Cardiovascular System Drugs

Pharmaceuticals, 2022
(1) Background: High-altitude hypoxia has been shown to affect the pharmacokinetic properties of drugs. Although there is a high incidence of cardiovascular disease among individuals living in high-altitude areas, studies on the effect of high-altitude ...
Junbo Zhu, Yabin Duan, Delong Duo, Jianxin Yang, Xue Bai, Guiqin Liu, Qian Wang, Xuejun Wang, Ning Qu, Yang Zhou, Xiangyang Li   +10 more
doaj   +1 more source

Genetic and immune changes in Tibetan high-altitude populations contribute to biological adaptation to hypoxia

Environmental Health and Preventive Medicine, 2022
Background: Tibetans have lived at very high altitudes for thousands of years, and have a distinctive suite of physiological traits that enable them to tolerate environmental hypoxia.
Jun Bai, Lijuan Li, Yanhong Li, Liansheng Zhang   +3 more
doaj   +1 more source