Results 91 to 100 of about 903,079 (310)

Variation in the apparent faecal digestibility of macronutrients and urinary energy excretion for three diets varying in fat and fibre content-- assessment of the Atwater factors and related energy conversion factors : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Nutritional Science at Massey University, Palmerston North, New Zealand [PDF]

, 2007
Background: Current systems to estimate dietary metabolisable energy (ME), often based on Atwater factors, assume that diet ME can be accurately predicted based on a few chemical components and that the ME of components is constant across foods ...
Zou, Maggie Long
core  

The Effects of a High Fat Meal on Blood Flow Regulation during Arm Exercise [PDF]

, 2020
A diet high in saturated fats results in endothelial dysfunction and can lead to atherosclerosis, a precursor to cardiovascular disease. Exercise training is a potent stimulus though to mitigate the negative effects of a high saturated fat diet; however,
Autler, Aaron, Bohmke, Natalie J., Chiu, Alexander, Franco, R. Lee, Garten, Ryan S., Henderson, Eric, Pederson, Lauren, Reed, Hunter, Richardson, Jacob, Via, Jeremy O.   +9 more
core   +1 more source

Copolymers of Poly(Butylene Trans‐1,4‐Cyclohexanedicarboxylate)/Pripol as New Biomaterial Platform for Small Diameter Vascular Graft

Advanced Healthcare Materials, EarlyView.
Electrospun tubular scaffolds from novel PBCE‐based copolyesters and blends were designed as candidates for small‐diameter vascular grafts. They combine defect‐free architecture, blood‐compatible surfaces, and mechanical properties comparable to native vessels.
Edoardo Bondi, Gabriele Obino, Giulia Guidotti, Alberto Sensini, Martijn van Griensven, Antonio Junior Lepedda, Nadia Lotti, Lorenzo Moroni   +7 more
wiley   +1 more source

High dietary fat intake increases fat oxidation and reduces skeletal muscle mitochondrial respiration in trained humans. [PDF]

, 2018
High-fat, low-carbohydrate (CHO) diets increase whole-body rates of fat oxidation and down-regulate CHO metabolism. We measured substrate utilization and skeletal muscle mitochondrial respiration to determine whether these adaptations are driven by high ...
Adam J. Trewin, Borg G. A., Brooke L. Devlin, Burke L. M., Carey A. L., Churchley E. G., Evans W.J., Evelyn B. Parr, Havemann L., Helge J. W., James P. Morton, Jill J. Leckey, John A. Hawley, Louise M. Burke, Nigel K. Stepto, Nolan J. Hoffman, Peronnet F., Skovbro M., Yeo W. K.   +18 more
core   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury.

PLoS ONE, 2014
RationaleHigh-fat diet with obesity-associated co-morbidities triggers cardiac remodeling and renders the heart more vulnerable to ischemia/reperfusion injury.
Ben Littlejohns, Philippe Pasdois, Simon Duggan, Andrew R Bond, Kate Heesom, Christopher L Jackson, Gianni D Angelini, Andrew P Halestrap, M-Saadeh Suleiman   +8 more
doaj   +1 more source

Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. [PDF]

, 2017
Obesity-associated insulin resistance plays a central role in type 2 diabetes. As such, tyrosine phosphatases that dephosphorylate the insulin receptor (IR) are potential therapeutic targets.
Aleshin, Alexander E, Ardecky, Robert J, Bankston, Laurie A, Barquilla, Antonio, Bliss, Matthew R, Bobkov, Andrey A, Bottini, Nunzio, Cadwell, Gregory W, Chung, Thomas DY, Ganji, Santhi R, Hedrick, Michael P, Khare, Shilpi, Kiselar, Janna, Liddington, Robert C, Liu, Yingge, Mustelin, Tomas, Pinkerton, Anthony B, Schenk, Simon, Stanford, Stephanie M, Yamamoto, Fusayo, Yu, Jinghua, Zhang, Vida, Zou, Jiwen   +22 more
core   +2 more sources

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Switching from a high-fat cellulose diet to a high-fat pectin diet reverses certain obesity-related morbidities

Nutrition & Metabolism, 2018
Background Reducing caloric intake is a proven intervention for mitigating and modulating morbidities associated with overnutrition. Caloric restriction is difficult to affect clinically, therefore, dietary interventions that ameliorate the adverse ...
Julie K. Bray, Gabriel S. Chiu, Leslie K. McNeil, Morgan L. Moon, Robyn Wall, Albert E. Towers, Gregory G. Freund   +6 more
doaj   +1 more source