Results 101 to 110 of about 620,339 (314)

Inulin oligofructose attenuates metabolic syndrome in high-carbohydrate, high-fat diet-fed rats [PDF]

, 2016
Prebiotics alter bacterial content in the colon, and therefore could be useful for obesity management. We investigated the changes following addition of inulin oligofructose (IO) in the food of rats fed either a corn starch (C) diet or a high ...
Ward, Leigh C., Kumar, Senthil A., Brown, Lindsay   +2 more
core   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Beneficial effects of lingonberry (Vaccinium vitis-idaea L.) supplementation on metabolic and inflammatory adverse effects induced by high-fat diet in a mouse model of obesity.

PLoS ONE, 2020
Obesity is a constantly increasing health problem worldwide. It is associated with a systemic low-grade inflammation, which contributes to the development of metabolic disorders and comorbidities such as type 2 diabetes. Diet has an important role in the
Riitta Ryyti, Mari Hämäläinen, Rainer Peltola, Eeva Moilanen   +3 more
doaj   +1 more source

Rutin Attenuates Non-Alcoholic Steatohepatitis in High Carbohydrate-High Fat Diet-Fed Rats

, 2011
Background and Aims: Non-alcoholic fatty liver disease (NAFLD) is frequently associated with the signs of metabolic syndrome, especially obesity, dyslipidaemia and insulin resistance.
Arumugam, T. V., Panchal, SK, Poudyal, H, Poudyal, Hemant, H. Poudyal, Panchal, Sunil K. (R20071), S.K. Panchal, Arumugam, TV, Arumugam, Thiruma V., L. Brown, Panchal, S. K., Brown, Lindsay, Poudyal, H., T.V. Arumugam, Brown, L., Brown, L   +15 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury.

PLoS ONE, 2014
RationaleHigh-fat diet with obesity-associated co-morbidities triggers cardiac remodeling and renders the heart more vulnerable to ischemia/reperfusion injury.
Ben Littlejohns, Philippe Pasdois, Simon Duggan, Andrew R Bond, Kate Heesom, Christopher L Jackson, Gianni D Angelini, Andrew P Halestrap, M-Saadeh Suleiman   +8 more
doaj   +1 more source

Effect of age on high-fat diet-induced hypertension

American Journal of Physiology-Heart and Circulatory Physiology, 2011
Aging and obesity both have a significant impact on central blood pressure (BP) regulation, and previous studies indicated that changes in central redox signaling with age may affect high-fat (HF) diet-induced cardiovascular responses. Therefore, we investigated the effects of 60% HF feeding on BP regulation in young adult (5 mo) and old (26 mo ...
Erdos, Benedek, Kirichenko, Nataliya, Whidden, Melissa, Basgut, Bilgen, Woods, Mary, Cudykier, Idan, Tawil, Rabih, Scarpace, Philip J., Tumer, Nihal   +8 more
openaire   +5 more sources

Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity

, 2018
Diet-induced obesity is strongly associated with nonalcoholic fatty-liver disease (NAFLD) and insulin resistance. We aimed to investigate the in vivo therapeutic value of tetrahydrocurcumin (THC) intervention in high-fat-diet (HFD)-induced obesity and ...
Zwe-Ling Kong (790856), Jin-Wun Chen (5982581), Chi-Tang Ho (195145), Jin-Wun Chen, Ching-Shu Lai (659309), Zwe-Ling Kong, Ching-Shu Lai, Min-Hsiung Pan (132700), Jia-Ching Wu (5982584), Min-Hsiung Pan, Chi-Tang Ho, Jia-Ching Wu   +11 more
core   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source