Results 1 to 10 of about 10,732 (178)

Interobserver Variability in the Diagnosis of High-Grade Prostatic Intraepithelial Neoplasia in a Tertiary Hospital in Northern Jordan [PDF]

Clinical Pathology, 2020
Prostate intraepithelial neoplasia is described as a precursor lesion to prostatic adenocarcinoma. High-grade prostate intraepithelial neoplasia (HGPIN) is classified as both grade 2 and 3 prostate intraepithelial neoplasia due to inconsistency between ...
Najla Aldaoud, Amer Hallak, Nour Abdo, Samir Al Bashir, Noor Marji, Ashley Graboski-Bauer   +5 more
doaj   +2 more sources

High-grade prostatic intraepithelial neoplasia. [PDF]

Korean J Urol, 2012
High-grade prostatic intraepithelial neoplasia (HGPIN) has been established as a precursor to prostatic adenocarcinoma. HGPIN shares many morphological, genetic, and molecular signatures with prostate cancer. Its predictive value for the development of future adenocarcinoma during the prostate-specific antigen screening era has decreased, mostly owing ...
Klink JC, Miocinovic R, Magi Galluzzi C, Klein EA.   +3 more
europepmc   +4 more sources

ERG expression in prostate cancer biopsies with and without high-grade prostatic intraepithelial neoplasia: a study in Jordanian Arab patients [PDF]

Research and Reports in Urology, 2019
Najla Aldaoud,1,2 Ashley Graboski-Bauer,3 Nour Abdo,4 Samir Al Bashir,1,2 Ashraf O Oweis,5 Hanadi Ebwaini,1 Yousef Hasen,1–2,6 Rami Alazab,7 Kiril Trpkov81Department of Pathology and Microbiology, King Abdullah University Hospital, Irbid, Jordan ...
Aldaoud N, Graboski-Bauer A, Abdo N, Al Bashir S, Oweis AO, Ebwaini H, Hasen Y, Alazab R, Trpkov K   +8 more
doaj   +2 more sources

Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer [PDF]

BMC Cancer, 2006
Background Molecular markers identifying alterations in proliferation and apoptotic pathways could be particularly important in characterizing high-risk normal or pre-neoplastic tissue. We evaluated the following markers: Ki67, Minichromosome Maintenance
Yang Ximing J, Deaton Ryan J, Ananthanarayanan Vijayalakshmi, Pins Michael R, Gann Peter H   +4 more
doaj   +4 more sources

Molecular Pathology of High-Grade Prostatic Intraepithelial Neoplasia: Challenges and Opportunities. [PDF]

Cold Spring Harb Perspect Med, 2019
A better understanding of the early stages of prostate cancer initiation, potentially arising from precursor lesions, may fuel development of powerful approaches for prostate cancer prevention or interception. The best-known candidate for such a precursor lesion has been referred to as high-grade prostatic intraepithelial neoplasia (HGPIN).
Trabzonlu L, Kulac I, Zheng Q, Hicks JL, Haffner MC, Nelson WG, Sfanos KS, Ertunc O, Lotan TL, Heaphy CM, Meeker AK, Yegnasubramanian S, De Marzo AM.   +12 more
europepmc   +6 more sources

Inverted (hobnail) high-grade prostatic intraepithelial neoplasia and invasive inverted pattern. [PDF]

Oncol Lett, 2015
High-grade prostatic intraepithelial neoplasia (HGPIN) is considered to be an important precursor for prostatic adenocarcinoma. The present study aimed to investigate the histological features of the uncommon inverted (hobnail) pattern of HGPIN in transrectal ultrasonographic (TRUS) prostatic needle biopsies from 13 cases.
Öznur M, Koca SB, Yildiz P, Bahadir B, Behzatoğlu K.   +4 more
europepmc   +6 more sources

Why do we keep reporting high-grade prostatic intraepithelial neoplasia (HGPIN)? [PDF]

International Brazilian Journal of Urology, 2016
Katia R. M. Leite
doaj   +2 more sources

Metabolic syndrome diagnosis and widespread high grade prostatic intraepithelial neoplasia significantly increase prostate cancer risk: results from a multicenter biopsy study. [PDF]

BMC Cancer, 2016
Cicione A, De Nunzio C, Tubaro A, Cantiello F, Manno S, Oliveira C, Lima E, Damiano R.   +7 more
europepmc   +2 more sources

The impact of zinc and testosterone co-treatment on tumourigenesis in prostate cancer: a novel model [PDF]

BMC Cancer
Background Pre-clinical models play a key role in prostate cancer research, helping to understand the mechanism of the disease. The unavailability of suitable animal models in under-resourced areas, such as in sub-Saharan African (SSA) countries ...
Kofi Oduro Yeboah, Paul Atawuchugi, Fredrick Kwadwo Baah, Bernard Elikplim Petershie, Yolanda Ashie, Eric Boakye-Gyasi, Newman Osafo, Emmanuel Amankwah Ntim, George Ainooson   +8 more
doaj   +2 more sources

High-grade prostatic intraepithelial neoplasia [PDF]

Modern Pathology, 2004
High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely preinvasive stage of adenocarcinoma, almost two decades after its first formal description. PIN has a high predictive value as a marker for adenocarcinoma, and its identification warrants repeat biopsy for concurrent or subsequent invasive carcinoma. The only method
David G, Bostwick, Junqi, Qian
openaire   +2 more sources