Results 91 to 100 of about 10,771 (216)

PTEN protein loss by immunostaining: Analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients [PDF]

, 2011
PURPOSE: Analytically validated assays to interrogate biomarker status in clinical samples are crucial for personalized medicine. PTEN is a tumor suppressor commonly inactivated in prostate cancer that has been mechanistically linked to disease ...
De Marzo, Angelo M, Esopi, David, Gurel, Bora, Han, Misop, Hicks, Jessica L, Humphreys, Elizabeth, Isaacs, William B, Liu, Wennuan, Lotan, Tamara L, Netto, George J, Park, Ben H, Partin, Alan W, Sutcliffe, Siobhan, Xu, Jianfeng   +13 more
core   +2 more sources

Significance of high-grade prostatic intraepithelial neoplasia on needle biopsy

Human Pathology, 1993
We studied 33 cases with an initial needle biopsy of the prostate that showed only high-grade prostatic intraepithelial neoplasia (PIN 2-3), for which follow-up biopsies were available. Twenty-four men (73%) were shown to have adenocarcinoma either on a simultaneous (14 patients) or subsequent (10 patients) biopsy.
M H, Weinstein, J I, Epstein
openaire   +2 more sources

European Code Against Cancer, 5th edition – organised cancer screening programmes

Molecular Oncology, Volume 20, Issue 1, Page 134-153, January 2026.
ECAC5 updates cancer prevention recommendations on cancer screening. Individuals are recommended to take part in organised screening programmes for colorectal, breast, cervical and lung cancer, as recommended in their country. Policymakers should aim to implement sustainable, organised screening programmes for these cancer types to facilitate their ...
Esther Toes‐Zoutendijk, Marc Arbyn, Anssi Auvinen, David Baldwin, Xavier Castells, Andrea DeCensi, Solveig Hofvind, Urska Ivanus, Carlo Senore, Mangesh Thorat, Carlijn van der Aalst, Ana Carolina Pereira Nunes Pinto, Javier Bracchiglione, Ariadna Feliu, Hajo Zeeb, Erica D'Souza, David Ritchie, Carolina Espina, Andre L. Carvalho, Iris Lansdorp‐Vogelaar   +19 more
wiley   +1 more source

MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

JCI Insight, 2023
Increased mitochondrial function may render some cancers vulnerable to mitochondrial inhibitors. Since mitochondrial function is regulated partly by mitochondrial DNA copy number (mtDNAcn), accurate measurements of mtDNAcn could help reveal which cancers
Jiayu Chen, Qizhi Zheng, Jessica L. Hicks, Levent Trabzonlu, Busra Ozbek, Tracy Jones, Ajay M. Vaghasia, Tatianna C. Larman, Rulin Wang, Mark C. Markowski, Sam R. Denmeade, Kenneth J. Pienta, Ralph H. Hruban, Emmanuel S. Antonarakis, Anuj Gupta, Chi V. Dang, Srinivasan Yegnasubramanian, Angelo M. De Marzo   +17 more
doaj   +1 more source

Cyclooxygenase-2 (COX-2): a molecular target in prostate cancer [PDF]

, 2007
[Abstract] Epidemiological studies provided the first evidence that COX may be involved in the pathogenesis of cancer. In the process of carcinogenesis and in the route of intracellular signalling during carcinogenesis, COX-2 expression may be a ...
Antón-Aparicio, Luis M., Aparicio Gallego, Guadalupe, Casinello Espinosa, J., Díaz-Prado, Silvia, García Campelo, Rosario, Jiménez Fonseca, P.   +5 more
core   +2 more sources

TMPRSS2-ERG Gene Fusion Causing ERG Overexpression Precedes Chromosome Copy Number Changes in Prostate Carcinomas, Paired HGPIN Lesions

Neoplasia: An International Journal for Oncology Research, 2006
TMPRSS2-ETS gene fusions have been found recurrently in prostate carcinomas, but not in the presumed precursor lesion, high-grade prostatic intraepithelial neoplasia (HGPIN). However, HGPIN lesions may share chromosomal changes with prostate cancer.
Nuno Cerveira, Franclim R. Ribeiro, Ana Peixoto, Vera Costa, Rui Henrique, Carmen Jerönimo, Manuel R. Teixeira   +6 more
doaj   +1 more source

Glyoxalase 1 Expression as a Novel Diagnostic Marker of High-Grade Prostatic Intraepithelial Neoplasia in Prostate Cancer. [PDF]

Cancers (Basel), 2021
Rounds L, Nagle RB, Muranyi A, Jandova J, Gill S, Vela E, Wondrak GT.   +6 more
europepmc   +1 more source

بررسی شيوع نئوپلازی داخل اپی‌تليالی با درجه بالا در نمونه‌های پروستات و همراهی آن با کانسر پروستات در مراجعه‌کنندگان به بيمارستان شهيد هاشمی‌نژاد از سال 1378 لغايت 1379 [PDF]

, 2003
هدف از اين مطالعه بررسی شيوع نئوپلازی داخل اپی‌تليالی پروستات با درجه بالا و همراهی آن با کانسر پروستات بوده است. در اين مطالعه اسلايدهای 137 مورد نمونه‌ پروستات از سال 1378 لغايت 1379 در بيمارستان شهيد هاشمی نژاد که شامل بيوپسی سوزنی، توتال پروستاتکتومی
حاجی‌حسينی, امیرعباس, عسگری, مژگان   +1 more
core  

No effect of a high-fat diet on promotion of sex hormone-induced prostate and mammary carcinogenesis in the Noble rat model [PDF]

, 2014
Department of Nursing and Health SciencesAuthor name used in this publication: I. F. F. BenzieAuthor name used in this publication: G.
Benzie, IFF, Cheung, A, Leung, G, Tsao, SW, Wong, YC   +4 more
core   +1 more source

Vascular endothelial growth factor (VEGF) and prostate pathology

International Brazilian Journal of Urology, 2010
PURPOSE: Previous studies suggest that vascular endothelial growth factor (VEGF) circulating levels might improve identification of patients with prostate cancer but results are conflicting.
Francisco Botelho, Francisco Pina, Pedro Silva, Gabriela Figueiredo, Francisco Cruz, Nuno Lunet   +5 more
doaj   +1 more source