Results 11 to 20 of about 10,771 (216)

5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores. [PDF]

PLoS ONE, 2017
The contribution of 5α-reductase 1 and 5α-reductase 2 to prostate cancer development and progression is not clearly understood. TRAMP mice are a common prostate cancer model, in which 5α-reductase 1 and 5α-reductase 2 expression levels, along with ...
Alexander B Opoku-Acheampong, Jamie N Henningson, Amanda P Beck, Brian L Lindshield   +3 more
doaj   +1 more source

Expression of nuclear Ki-67 antigen in prostatic high grade intraepithelial neoplasia and prostatic carcinoma [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. Prostatic intraepithelial high grade neoplasia (PINHG) is accepted as preneoplastic lesion in prostatic carcinoma. One of the fundamental events in early oncogenesis is the disruption of proliferative activity.
Janković-Veličković Ljubinka, Đorđević Biljana, Rančić Gorana, Marjanović Goran   +3 more
doaj   +1 more source

Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. [PDF]

PLoS ONE, 2013
The inhibitor of apoptosis protein survivin is expressed in most cancers. Using the conditional PTEN deletion mouse model, we previously reported that survivin levels increase with prostate tumor growth.
Helty Adisetiyo, Mengmeng Liang, Chun-Peng Liao, Ari Aycock-Williams, Michael B Cohen, Shili Xu, Nouri Neamati, Edward M Conway, Chieh-Yang Cheng, Alexander Yu Nikitin, Pradip Roy-Burman   +10 more
doaj   +1 more source

Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice [PDF]

, 2013
A role for microbes has been suspected in prostate cancer but difficult to confirm in human patients. We show here that a gastrointestinal (GI) tract bacterial infection is sufficient to enhance prostate intraepithelial neoplasia (PIN) and microinvasive ...
A Peled, AM De Marzo, AR Moser, Bruce H. Horwitz, Chung-Wei Lee, D Giri, Deyu Fang, E Derhovanessian, E Gounaris, F Balkwill, GA Rook, GE Steiner, GS Palapattu, H Biermann, J Folkman, James G. Fox, JE Montie, JG Fox, JG Fox, JG Fox, KC Valkenburg, Kelsey Cappelle, KJ Bruxvoort, M Royuela, Michael Doulberis, MJ Bissell, P Correa, Q Zhang, R Jabeen, S Wu, SB Shappell, SE Erdman, SE Erdman, SI Grivennikov, Susan E. Erdman, T Poutahidis, Tatiana Levkovich, Theofilos Poutahidis, TJ Jerde, VP Rao, WA Sakr, WG Nelson, WJ Chae, Zhongming Ge   +43 more
core   +18 more sources

Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]

, 2006
The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen, Cviko, Aida, Krušlin, Božo, Odak, Ljubica, Tomas, Davor, Čupić, Hrvoje   +5 more
core   +1 more source

Death receptor 5 expression is inversely correlated with prostate cancer progression. [PDF]

, 2014
Prostate carcinoma (PCa) is one of the most common cancers in men. Prostate-specific antigen (PSA) has been widely used to predict the outcome of PCa and screening with PSA has resulted in a decline in mortality. However, PSA is not an optimal prognostic
Antonio-Andres, Gabriela, Bonavida, Benjamin, Gonzalez-Bonilla, Cesar, Hernandez-Cueto, Angeles, Hernandez-Cueto, Daniel, Huerta-Yepez, Sara, Jimenez-Gutierrez, Carlos, Mendoza-Marin, Marisela, Mora-Campos, Rosario, Sandoval-Mejia, Ana Lilia, Vega, Mario I   +10 more
core   +1 more source

Prostatic intraepithelial neoplasia- the story evolves

Journal of Pathology of Nepal, 2016
Prostatic intraepithelial neoplasia is preneoplastic lesion described from early of this 20th century. PIN includes a spectrum of features ranging from low grade to high grade neoplasia. The studies are focused on their influence to predict the occurence
SV Pradhan, P Sharan
doaj   +1 more source

Hepsin immunohistochemical expression in prostate cancer in relation to Gleason′s grade and serum prostate specific antigen

Indian Journal of Pathology and Microbiology, 2011
Background: Hepsin (HPN), a type II trans-membrane serine protease, has been reported to be one of the most up regulated genes in prostate cancer. The aim of the present study was to find out immuno-histochemistry based phenotypic expression of HPN in ...
Madhu Mati Goel, Dhamita Agrawal, S M Natu, Apul Goel   +3 more
doaj   +1 more source

Prostatic adenocarcinoma with a peculiar morphology – a rare case of pseudohyperplastic variant with inverted polarity

Surgical and Experimental Pathology, 2022
Background The inverted (hobnail) variant of high-grade prostatic intraepithelial neoplasia (HGPIN) has been reported in two previous series and one case of inverted polarity in invasive adenocarcinoma has been reported. We reported an additional case of
Daniel Abensur Athanazio, Maiara Ferreira de Souza, Maria Estela Pompeu do Amaral   +2 more
doaj   +1 more source

MicroRNA-551b expression profile in low and high-grade cervical intraepithelial neoplasia [PDF]

, 2018
OBJECTIVE: To evaluate the expression of microRNA (miR)-551b in patients with low and high grade cervical intraepithelial neoplasia (CIN) and to find an association with high-risk Human Papillomavirus (HR-HPV) infection-related prognostic biomarkers ...
Bordi, G, Carico, E, Caserta, D, DE VITIS, C, DI PROPERZIO, M, Giglio, S, Lukic, A, Mancini, R.   +7 more
core   +1 more source