The multi-protective role of dietary betaine in largemouth bass (<i>Micropterus salmoides</i>): coordinating antioxidant, inflammatory, and metabolic homeostasis under high-fat diet stress. [PDF]
Liu YJ, Guo J, Li CD, Han SY, Cai L.
europepmc +1 more source
N. Luscombe, M. Noakes, P. Clifton
semanticscholar +1 more source
F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu +16 more
wiley +1 more source
Dietary Amylose/Amylopectin Ratio Modulated Growth Performance, Intestinal Health, and Lipid Metabolism in Goslings Fed Low-Protein Diets. [PDF]
Xing X +5 more
europepmc +1 more source
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li +9 more
wiley +1 more source
Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In-Depth Review. [PDF]
Arshad MT +7 more
europepmc +1 more source
Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang +11 more
wiley +1 more source
Optimal Dietary α-Starch Requirement and Its Effects on Growth and Metabolic Regulation in Chinese Hook Snout Carp (<i>Opsariichthys bidens</i>). [PDF]
Cai W +7 more
europepmc +1 more source

