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Signal Detection in High-Resolution Mass Spectrometry Data
Journal of Proteome Research, 2008Mass spectrometry data from high-resolution time-of-flight instruments often contain a vast number of noninformative background-ion peaks whose signal is similar to that of peptide peaks. Consequently, seeking peptide signal in these spectra based on a signal-to-noise ratio will remove signal peaks as well as noise.
Dale F, McLerran +4 more
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High-resolution tandem mass spectrometry of carbonic anhydrase
Analytical Chemistry, 1994Electrospray ionization of carbonic anhydrase with ion dissociation yields a mass spectrum from which the masses of > 100 isotopic clusters are determined accurately, with the number of charges assigned directly from resolved isotopic peaks. Of these clusters, 80% correspond to fragmentation at or near the amino acid proline. The masses of combinations
M W, Senko, S C, Beu, F W, McLafferty
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High‐Resolution Ion Mobility Spectrometry–Mass Spectrometry on Poly(methyl methacrylate)
Angewandte Chemie International Edition, 2010Further dimensions: The title mass spectrometric technique offers an extra dimension of separation based on size and conformation of the molecules in addition to m/z separation without the need of time-consuming liquid chromatography separation. Detailed mapping of the mass and drift time separated ions allowed identification of end groups originating ...
Song, J. +4 more
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Mass Spectrometry and High Resolution Mass Spectrometry: An Overview
2017In this chapter, a brief overview of fundamentals in mass spectrometry and some applications are presented. The main concepts in ionization techniques, classical techniques and ambient mass spectrometry are followed by an overview on analyzers.
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High-Resolution Mass Spectrometry for Untargeted Drug Screening
2016While gas chromatography-mass spectrometry (GC/MS) continues to be the forensic standard for toxicology, liquid chromatography coupled to tandem MS offers significant operational advantages for targeted confirmatory analysis. LC-high-resolution (HR)-MS has recently been available that offers advantages for untargeted analysis.
Alan H B, Wu, Jennifer, Colby
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High-resolution mass spectrometry
2020M. Ariel Geer Wallace, James P. McCord
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High resolution mass spectrometry of natural products
Pure and Applied Chemistry, 1964Abstract
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High Resolution Mass Spectrometry
The Journal of Chemical Physics, 1951Clifford E. Berry, S. M. Rock
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