Results 71 to 80 of about 530,809 (300)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Synthesis, Characterization and Thermal Properties of Alkyl-functional Naphthoxazines [PDF]

, 2013
Cataloged from PDF version of article.A series of alkyl-functional naphthoxazine resins having various alkyl chain lengths from C1 to C18 are synthesized with a high yield and high purity by the reactions of 1,5-dihydroxynaphthalene, formaldehyde, and ...
Agag, Allen, Chaisuwan, Chernykh, Chernykh, Ghosh, Ishida, Ishida, Ishida, Kiskan, Martiskainen, Ning, Shen, Shen, Szatmari, Szatmari, Uyar, Velez-Herrera, Velez-Herrera, Wang, Yagci, Yildirim   +21 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Proteome data of Anopheles stephensi ovary using high-resolution mass spectrometry

Data in Brief, 2018
This article contains data on the proteins expressed in the ovaries of Anopheles stephensi, a major vector of malaria in India. Data acquisition was performed using a high-resolution Orbitrap-Velos mass spectrometer.
Gourav Dey, Ajeet Kumar Mohanty, Manish Kumar, Sreelakshmi K. Sreenivasamurthy, Arun H. Patil, T.S. Keshava Prasad, Ashwani Kumar   +6 more
doaj   +1 more source

Heparin Isomeric Oligosaccharide Separation Using Volatile Salt Strong Anion Exchange Chromatography [PDF]

, 2016
The complexity of heparin and heparan sulfate saccharides makes their purification, including many isomeric structures, very challenging and is a bottleneck for structure–activity studies.
Austin, JA, Blocksidge, J, Guimond, SE, Leary, JA, Miller, RL, Shivkumar, M, Turnbull, JE   +6 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

DIESEL CHARACTERIZATION BY HIGH RESOLUTION MASS SPECTROMETRY-GAS CHROMATOGRAPHY

CT&F Ciencia, Tecnología & Futuro, 1998
High-resolution mass spectrometry-gas chromatography is combined with the HC22 method in order to obtain a detailed information about the chemical composition of diesel and the distribution of different compound types in terms of its final boiling ...
C.A BALDRICHF
doaj  

Nitric oxide adsorption on Ru(001) at 78 and 120 K: Temperature dependence on the bonding geometry [PDF]

, 1987
The influence of surface temperature on NO adsorption on Ru(001) between 78 and 120 K has been investigated by high-resolution electron energy-loss spectroscopy (EELS) and thermal desorption mass spectrometry.
Schwalke, Udo, Weinberg, W. H.
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

High Resolution Mass Spectrometry Fragmentation Rules of Etomidate and Its Structural Analogues

Fayixue Zazhi
ObjectiveTo explore the characteristic fragment ions, ion abundance ratios and mass spectrometry fragmentation rules of etomidate and its structural analogues by using gas chromatography-quadrupole/orbitrap mass spectrometry （GC-Q/Orbitrap MS） and liquid
FAN Xian-yu, ZHU Xue-yan, WANG Xin, XIANG Ping, ZHAO Jun-bo   +4 more
doaj   +1 more source