Ultra-high performance liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) is a powerful and essential technique for metabolite annotation in untargeted metabolomic applications.
Julian Pezzatti +4 more
doaj +1 more source
Testing Luminescence Dating Methods for Small Samples from Very Young Fluvial Deposits [PDF]
The impetus behind this study is to understand the sedimentological dynamics of very young fluvial systems in the Amazon River catchment and relate these to land use change and modern analogue studies of tidal rhythmites in the geologic record.
Archer, Allen W. +3 more
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Analysis of Hydrogen Isotope Abundance by High Resolution Isotope Ratio Mass Spectrometry
High resolution isotope ratio mass spectrometry (HR-IRMS) is often used to measure the abundance of deuterium to verify the efficiency of isotope isolation of a cryogenic distillation column system.
Chao WU +5 more
doaj +1 more source
Calculation of molecular formulas in high-resolution mass spectrometry [PDF]
Algorithm, decimal weights, and molecular formulas calculated by computer for high-resolution mass spectrometry ...
Lederberg, J.
core +1 more source
Extraction and cleansing of data for a non-targeted analysis of high-resolution mass spectrometry data of wastewater [PDF]
We provide a workflow to extract unidentified signals from chromatography-high resolution mass spectrometry (LC-HRMS) data of wastewater samples as a pre-step of a non-targeted analysis of dissolved organic matter (DOM).
Petrovic, Mira +2 more
core +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The data presented in this article are related to the research article entitled “13C labeling analysis of sugars by high resolution-mass spectrometry for Metabolic Flux Analysis” (Acket et al., 2017) [1].
Sébastien Acket +3 more
doaj +1 more source
High resolution mass spectrometry in molecular structure and stereochemical studies - Effect of stereochemistry on the fragmentation of epimeric derivatives of azabicycloalkanes [PDF]
High resolution mass spectrometry in studies of stereochemistry effect on fragmentation of epimeric derivatives of ...
Burlingame, A. L. +2 more
core +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source

