Results 21 to 30 of about 1,151,593 (279)

Association between LRP1 C766T polymorphism and Alzheimer’s disease susceptibility: a meta-analysis

open access: yesScientific Reports, 2017
Low density lipoprotein receptor-related protein 1 (LRP1) C766T polymorphism (rs1799986) has been extensively investigated for Alzheimer’s disease (AD) susceptibility. However, results in different studies have been contradictory. Therefore, we conducted
Yun Wang   +9 more
doaj   +1 more source

High-throughput 18K SNP array to assess genetic variability of the main grapevine cultivars from Sicily [PDF]

open access: yes, 2016
The viticulture of Sicily, for its vocation, is one of the most important and ancient forms in Italy. Autochthonous grapevine cultivars, many of which known throughout the world, have always been cultivated in the island from many centuries. With the aim
A Dereeper   +91 more
core   +1 more source

High-throughput polyribosome fractionation [PDF]

open access: yesNucleic Acids Research, 2004
Polyribosome sedimentation velocity centrifugation can be used to identify differential regulation of the translation of mRNAs. However, ultracentrifugation presents practical limitations on the number of sedimentation velocity gradients that can be run simultaneously.
Yipeng, Wang   +4 more
openaire   +2 more sources

Integrative prediction of gene expression with chromatin accessibility and conformation data

open access: yesEpigenetics & Chromatin, 2020
Background Enhancers play a fundamental role in orchestrating cell state and development. Although several methods have been developed to identify enhancers, linking them to their target genes is still an open problem. Several theories have been proposed
Florian Schmidt   +2 more
doaj   +1 more source

Optimal Assembly for High Throughput Shotgun Sequencing [PDF]

open access: yes, 2013
We present a framework for the design of optimal assembly algorithms for shotgun sequencing under the criterion of complete reconstruction. We derive a lower bound on the read length and the coverage depth required for reconstruction in terms of the ...
Bresler, Guy   +2 more
core   +2 more sources

The Role of Non-Coding RNAs in the Human Placenta

open access: yesCells, 2022
Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs, and species, which has been broadly recognized since the human ENCODE project and several other genome projects.
Milena Žarković   +3 more
doaj   +1 more source

The High-Throughput Analyses Era: Are We Ready for the Data Struggle? [PDF]

open access: yes, 2018
Recent and rapid technological advances in molecular sciences have dramatically increased the ability to carry out high-throughput studies characterized by big data production.
D’Argenio, Valeria
core   +1 more source

High throughput flow cytometry [PDF]

open access: yesCytometry, 2001
Conventional flow cytometry does not allow the rapid analysis of multiple samples. This has limited its uses in drug discovery, for which the standard for throughput is 100,000 samples per day.We describe a simple method in which commercial peristaltic tubing is connected from a commercial autosampler to a flow cytometer.
F W, Kuckuck, B S, Edwards, L A, Sklar
openaire   +2 more sources

Corrosion of iron and nickel based alloys in sulphuric acid: Challenges and prevention strategies

open access: yesJournal of Materials Research and Technology, 2023
Sulphuric acid (H2SO4) is widely used in various industrial processes, including fertilizer production. However, its highly corrosive nature poses a significant challenge to the materials used for transport and storage, particularly metals and alloys ...
Ayoub Ouarga   +5 more
doaj   +1 more source

Interplay between transforming growth factor-β and Nur77 in dual regulations of inhibitor of differentiation 1 for colonic tumorigenesis

open access: yesNature Communications, 2021
Inhibitor of Differentiation 1 (ID1) is an oncogene for colorectal cancer. Here, the authors show a complex interplay between nuclear receptor Nur77 and Transforming Growth Factor-β (TGFβ) to regulate ID1 expression at both transcriptional and post ...
Boning Niu   +9 more
doaj   +1 more source

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