Current status of use of high throughput nucleotide sequencing in rheumatology [PDF]
RMD Open, 2021 Objective Here, we assess the usage of high throughput sequencing (HTS) in rheumatic research and the availability of public HTS data of rheumatic samples.Methods We performed a semiautomated literature review on PubMed, consisting of an R-script and ...
Andreas Schwarting +2 more
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Evaluation of MC1R high-throughput nucleotide sequencing data generated by the 1000 Genomes Project [PDF]
Genetics and Molecular Biology, 2017 The advent of next-generation sequencing allows simultaneous processing of several genomic regions/individuals, increasing the availability and accuracy of whole-genome data. However, these new approaches may present some errors and bias due to alignment,
Leonardo Arduino Marano +3 more
doaj +10 more sources
Correction: Current status of use of high throughput nucleotide sequencing in rheumatology [PDF]
RMD Open, 2021 Boegel S, Castle JC, Schwarting A. Current status of use of high throughput nucleotide sequencing in rheumatology. RMD Open 2021;7:e001324. doi: 10.1136/rmdopen-2020-001324 The article has been …
doaj +7 more sources
Neuropeptidergic Signaling in the American Lobster Homarus americanus: New Insights from High-Throughput Nucleotide Sequencing. [PDF]
PLoS ONE, 2015 Peptides are the largest and most diverse class of molecules used for neurochemical communication, playing key roles in the control of essentially all aspects of physiology and behavior.
Andrew E Christie +7 more
doaj +8 more sources
Correcting nucleotide-specific biases in high-throughput sequencing data [PDF]
BMC Bioinformatics, 2017 Background High-throughput sequence (HTS) data exhibit position-specific nucleotide biases that obscure the intended signal and reduce the effectiveness of these data for downstream analyses.
Jeremy R. Wang +2 more
doaj +8 more sources
Single-nucleotide polymorphism discovery by high-throughput sequencing in sorghum [PDF]
BMC Genomics, 2011 Background Eight diverse sorghum (Sorghum bicolor L. Moench) accessions were subjected to short-read genome sequencing to characterize the distribution of single-nucleotide polymorphisms (SNPs).
White Frank F +6 more
doaj +11 more sources
High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform [PDF]
Nature Communications, 2023 There exist challenges in quantifying the length of individual telomeres at single nucleotide resolution. Here the authors report a method to capture telomeres and accurately analyse their length in human cell lines and patient peripheral blood leukocyte
Cheng-Yong Tham +18 more
doaj +6 more sources
High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing [PDF]
Nature Communications, 2018 Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of ...
Peng Zhang +16 more
doaj +7 more sources
The discrepancy among single nucleotide variants detected by DNA and RNA high throughput sequencing data [PDF]
BMC Genomics, 2017 Background High throughput sequencing technology enables the both the human genome and transcriptome to be screened at the single nucleotide resolution. Tools have been developed to infer single nucleotide variants (SNVs) from both DNA and RNA sequencing
Yan Guo +4 more
doaj +6 more sources
BMC Bioinformatics, 2019 Background Methods to read out naturally occurring or experimentally introduced nucleic acid modifications are emerging as powerful tools to study dynamic cellular processes.
Tobias Neumann +6 more
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